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16 Results Found

  • Review
  • Open Access
446 Views
26 Pages

21 January 2026

The microbial cell wall is a dynamic structure responsible for maintaining the shape and integrity of the cell. It is involved in the processes of cell growth, reproduction and division, protection against environmental stress factors, bidirectional...

  • Article
  • Open Access
2 Citations
3,114 Views
16 Pages

Underwater Shock Wave-Enhanced Cavitation to Induce Morphological Changes and Cell Permeabilization in Microscopic Fungi

  • Miguel A. Martínez-Maldonado,
  • Blanca E. Millán-Chiu,
  • Francisco Fernández,
  • Daniel Larrañaga,
  • Miguel A. Gómez-Lim and
  • Achim M. Loske

22 March 2024

Since the discovery of extracorporeal lithotripsy, there has been an increased interest in studying shock wave-induced cavitation, both to improve this technique and to explore novel biotechnological applications. As shock waves propagate through flu...

  • Article
  • Open Access
14 Citations
5,085 Views
22 Pages

Characterization of the Burkholderia cenocepacia J2315 Surface-Exposed Immunoproteome

  • Sílvia A. Sousa,
  • António M.M. Seixas,
  • Manoj Mandal,
  • Manuel J. Rodríguez-Ortega and
  • Jorge H. Leitão

6 September 2020

Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect patients against Bcc infections is a highly attractive therapeuti...

  • Article
  • Open Access
14 Citations
3,435 Views
13 Pages

1 June 2021

Microbial fuel cells (MFCs) have attracted attention by directly converting the bioelectrochemical energy possessed by the organic materials that make up the biomass into electrical energy. In this study, the relationship between the biofilm formed o...

  • Article
  • Open Access
5 Citations
2,973 Views
19 Pages

Surface-Shaving of Staphylococcus aureus Strains and Quantitative Proteomic Analysis Reveal Differences in Protein Abundance of the Surfaceome

  • Anders Karlsson,
  • Leonarda Achá Alarcón,
  • Beatriz Piñeiro-Iglesias,
  • Gunnar Jacobsson,
  • Susann Skovbjerg,
  • Edward R. B. Moore,
  • Pradeep Kumar Kopparapu,
  • Tao Jin and
  • Roger Karlsson

Staphylococcus aureus is a pathogen known to cause a wide range of infections. To find new targets for identification and to understand host–pathogen interactions, many studies have focused on surface proteins. We performed bacterial-cell surfa...

  • Article
  • Open Access
12 Citations
4,199 Views
16 Pages

In Vitro Anti-Inflammatory Activity of Peptides Obtained by Tryptic Shaving of Surface Proteins of Streptococcus thermophilus LMD-9

  • Rania Allouche,
  • Zeeshan Hafeez,
  • Florent Papier,
  • Annie Dary-Mourot,
  • Magali Genay and
  • Laurent Miclo

16 April 2022

Streptococcus thermophilus, a lactic acid bacterium widely used in the dairy industry, is consumed regularly by a significant proportion of the population. Some strains show in vitro anti-inflammatory activity which is not fully understood. We hypoth...

  • Article
  • Open Access
10 Citations
3,432 Views
14 Pages

Search of Potential Vaccine Candidates against Trueperella pyogenes Infections through Proteomic and Bioinformatic Analysis

  • Ángela Galán-Relaño,
  • Lidia Gómez-Gascón,
  • Antonio Rodríguez-Franco,
  • Inmaculada Luque,
  • Belén Huerta,
  • Carmen Tarradas and
  • Manuel J. Rodríguez-Ortega

Trueperella pyogenes is an opportunistic pathogen, responsible for important infections in pigs and significant economic losses in swine production. To date, there are no available commercial vaccines to control diseases caused by this bacterium. In...

  • Article
  • Open Access
12 Citations
4,743 Views
22 Pages

Proteomic and Bioinformatic Analysis of Streptococcus suis Human Isolates: Combined Prediction of Potential Vaccine Candidates

  • Esther Prados de la Torre,
  • Antonio Rodríguez-Franco and
  • Manuel J. Rodríguez-Ortega

18 April 2020

Streptococcus suis is a Gram-positive bacterium responsible for major infections in pigs and economic losses in the livestock industry, but also an emerging zoonotic pathogen causing serious diseases in humans. No vaccine is available so far against...

  • Article
  • Open Access
7 Citations
3,831 Views
13 Pages

28 August 2021

Infections caused by the Gram-positive bacterium Streptococcus pneumoniae have become a major health problem worldwide because of their high morbidity and mortality rates, especially in developing countries. This microorganism colonizes the human upp...

  • Article
  • Open Access
2 Citations
2,283 Views
21 Pages

11 November 2022

Streptococcus thermophilus, a food grade bacterium, is extensively used in the manufacture of fermented products such as yogurt and cheeses. It has been shown that S. thermophilus strains exhibited varying anti-inflammatory activities in vitro. Our p...

  • Article
  • Open Access
4 Citations
3,254 Views
15 Pages

For potato crops, host resistance is currently the most effective and sustainable tool to manage diseases caused by the plasmodiophorid Spongospora subterranea. Arguably, zoospore root attachment is the most critical phase of infection; however, the...

  • Article
  • Open Access
2 Citations
2,678 Views
20 Pages

Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions

  • António M. M. Seixas,
  • Carolina Silva,
  • Joana M. M. Marques,
  • Patrícia Mateus,
  • Manuel J. Rodríguez-Ortega,
  • Joana R. Feliciano,
  • Jorge H. Leitão and
  • Sílvia A. Sousa

9 April 2024

Burkholderia cepacia complex infections remain life-threatening to cystic fibrosis patients, and due to the limited eradication efficiency of current treatments, novel antimicrobial therapies are urgently needed. Surface proteins are among the best t...

  • Article
  • Open Access
21 Citations
3,926 Views
22 Pages

Extracellular Vesicles in Human Preterm Colostrum Inhibit Infection by Human Cytomegalovirus In Vitro

  • Manuela Donalisio,
  • Simona Cirrincione,
  • Massimo Rittà,
  • Cristina Lamberti,
  • Andrea Civra,
  • Rachele Francese,
  • Paola Tonetto,
  • Stefano Sottemano,
  • Marcello Manfredi and
  • David Lembo
  • + 7 authors

Breast milk is a complex biofluid that nourishes infants, supports their growth and protects them from diseases. However, at the same time, breastfeeding is a transmission route for human cytomegalovirus (HCMV), with preterm infants being at a great...

  • Article
  • Open Access
4 Citations
4,338 Views
16 Pages

Topical Application of A New Herbal Complex, NI-01, Ameliorates House Dust Mite-Induced Atopic Dermatitis in NC/Nga Mice

  • Seong Eun Jin,
  • Hyekyung Ha,
  • Sae-Rom Yoo,
  • Woo-Young Jeon,
  • Nari Lee,
  • Mee-Young Lee,
  • Susanna Choi,
  • Ji-Hye Jang,
  • Eunsook Park and
  • Chang-Seob Seo
  • + 1 author

27 April 2020

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritus and cutaneous dry skin. Here, we investigated whether topical application of NI-01 composed of six herbal medicines has a therapeutic effect on AD in vivo. Twelve...

  • Article
  • Open Access
6 Citations
2,924 Views
13 Pages

Eflornithine Hydrochloride-Loaded Electrospun Nanofibers as a Potential Face Mask for Hirsutism Application

  • Shuruq S. Almuwallad,
  • Dunia A. Alzahrani,
  • Walaa S. Aburayan,
  • Ahmed J. Alfahad,
  • Khulud A. Alsulami,
  • Alhassan H. Aodah,
  • Samar A. Alsudir,
  • Sulaiman S. Alhudaithi and
  • Essam A. Tawfik

Hirsutism is a distressing condition that can affect women’s self-esteem due to the excessive amount of hair growth in different body parts, including the face. A temporary managing option is to develop a self-care routine to remove unwanted ha...

  • Article
  • Open Access
47 Citations
5,754 Views
24 Pages

Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated from Sanguisorba officinalis Roots Supported by Enhancing Re-Epithelization, Angiogenesis, Anti-Inflammatory, and Antimicrobial Effects

  • Walaa A. Negm,
  • Aya H. El-Kadem,
  • Engy Elekhnawy,
  • Nashwah G. M. Attallah,
  • Gadah Abdulaziz Al-Hamoud,
  • Thanaa A. El-Masry and
  • Ahmed Zayed

31 January 2022

A wound is a complicated bioprocess resulting in significant tissue damage, which is worsened by a secondary bacterial infection, commonly Pseudomonas aeruginosa and Staphylococcus aureus. The goal of our study was to investigate the metabolic profil...