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6 Results Found

  • Article
  • Open Access
4 Citations
2,727 Views
20 Pages

Unraveling the Binding Mode of Cyclic Adenosine–Inosine Monophosphate (cAIMP) to STING through Molecular Dynamics Simulations

  • Meiting Wang,
  • Baoyi Fan,
  • Wenfeng Lu,
  • Ulf Ryde and ,
  • Yuxiao Chang,
  • Di Han,
  • Jiarui Lu,
  • Taigang Liu,
  • Qinghe Gao and
  • Yongtao Xu
  • + 6 authors+ 1 author

The stimulator of interferon genes (STING) plays a significant role in immune defense and protection against tumor proliferation. Many cyclic dinucleotide (CDN) analogues have been reported to regulate its activity, but the dynamic process involved w...

(This article belongs to the Special Issue Recent Advances in Computer-Aided Drug Design and Drug Discovery)
  • Proceeding Paper
  • Open Access
1 Citations
1,483 Views
7 Pages

Myo-inositol is considered as an important osmoprotectant, which is directly involved in abiotic stress management in plants. We have biochemically and functionally characterized the inositol monophosphatase (CaIMP1) and IMP-like proteins (CaIMPL1 an...

(This article belongs to the Proceedings of The 2nd International Electronic Conference on Plant Sciences—10th Anniversary of Journal Plants)
  • Article
  • Open Access
94 Citations
7,649 Views
17 Pages

Mapping Grain Iron and Zinc Content Quantitative Trait Loci in an Iniadi-Derived Immortal Population of Pearl Millet

  • Sushil Kumar,
  • Charles Tom Hash,
  • Thirunavukkarasu Nepolean,
  • Mahesh D. Mahendrakar and ,
  • Chellapilla Tara Satyavathi,
  • Govind Singh,
  • Abhishek Rathore,
  • Rattan S. Yadav,
  • Rajeev Gupta and
  • Rakesh K. Srivastava
  • + 5 authors+ 0 author

11 May 2018

Pearl millet is a climate-resilient nutritious crop requiring low inputs and is capable of giving economic returns in marginal agro-ecologies. In this study, we report large-effect iron (Fe) and zinc (Zn) content quantitative trait loci (QTLs) using...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
562 Views
17 Pages

Phytochemical Profiling and Proteomic Insights into the Anti-Inflammatory Effects of Jing Guan Fang in LPS-Stimulated Macrophages

  • Seungyeon Yeon,
  • Muhammad A. Alsherbiny,
  • Yu-Ting Sun,
  • Mitchell N. Low and
  • Chun Guang Li

13 August 2026

Jing Guan Fang (JGF) is a traditional multi-herb formula used for hyperinflammatory conditions associated with severe viral infections; however, its protein-level effects in macrophage-mediated inflammation remain incompletely characterised. In this...

(This article belongs to the Special Issue Bioactive Compounds from Natural Sources with Antioxidant and Anti-Inflammatory Potential)
  • Article
  • Open Access
9 Citations
4,299 Views
22 Pages

30 September 2022

Currently, there are no specific therapeutics for flavivirus infections, including dengue virus (DENV) and Zika virus (ZIKV). In this study, we evaluated extracts from the plants Hedyotis diffusa (HD) and Artemisia capillaris (AC) to determine the an...

(This article belongs to the Special Issue Bioprospecting of Natural Products from Medicinal Plants)
  • Article
  • Open Access
1,477 Views
18 Pages

Metal nanoparticles (NP) are increasingly used in biomedical applications. Among them, silver NPs (AgNPs) are used as active components in antibacterial coatings for wound dressings, medical devices, implants, cosmetics, textiles, and food packaging....

(This article belongs to the Section Molecular Nanoscience)