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20 Results Found

  • Article
  • Open Access
8 Citations
2,946 Views
16 Pages

Comparing Viral Vectors and Fate Mapping Approaches for Astrocyte-to-Neuron Reprogramming in the Injured Mouse Cerebral Cortex

  • Matteo Puglisi,
  • Chu Lan Lao,
  • Gulzar Wani,
  • Giacomo Masserdotti,
  • Riccardo Bocchi and
  • Magdalena Götz

23 August 2024

Direct neuronal reprogramming is a promising approach to replace neurons lost due to disease via the conversion of endogenous glia reacting to brain injury into neurons. However, it is essential to demonstrate that the newly generated neurons origina...

  • Review
  • Open Access
32 Citations
8,069 Views
31 Pages

Impact of the Relative Age Effect on Competition Performance in Basketball: A Qualitative Systematic Review

  • Alfonso de la Rubia Riaza,
  • Jorge Lorenzo Calvo,
  • Daniel Mon-López and
  • Alberto Lorenzo

Performance in basketball is multifactorial. One of the modifying factors is the “Relative Age Effect—RAE”. However, its impact depends on the sample characteristics and sport context. The purpose of this study was to examine the in...

  • Article
  • Open Access
41 Citations
5,998 Views
14 Pages

Differential Timing and Coordination of Neurogenesis and Astrogenesis in Developing Mouse Hippocampal Subregions

  • Allison M. Bond,
  • Daniel A. Berg,
  • Stephanie Lee,
  • Alan S. Garcia-Epelboim,
  • Vijay S. Adusumilli,
  • Guo-li Ming and
  • Hongjun Song

26 November 2020

Neocortical development has been extensively studied and therefore is the basis of our understanding of mammalian brain development. One fundamental principle of neocortical development is that neurogenesis and gliogenesis are temporally segregated p...

  • Article
  • Open Access
24 Citations
6,043 Views
9 Pages

The New Generation of Professional Soccer Talent Is Born under the Bias of the RAE: Relative Age Effect in International Male Youth Soccer Championships

  • Benito Pérez-González,
  • Jairo León-Quismondo,
  • José Bonal,
  • Pablo Burillo and
  • Álvaro Fernández-Luna

2 December 2021

In 2019, numerous championships of youth categories soccer national teams were held. In the present study, we analyzed the existence of the Relative Age Effect (RAE) in four major male championships that, due to their importance and participating tea...

  • Article
  • Open Access
22 Citations
2,899 Views
9 Pages

Small Relative Age Effect Appears in Professional Female Italian Team Sports

  • Paolo Riccardo Brustio,
  • Gennaro Boccia,
  • Paolo De Pasquale,
  • Corrado Lupo and
  • Alexandru Nicolae Ungureanu

The relative age effect (RAE) concerns those (dis)advantages and outcomes resulting from an interaction between the dates of selection and birthdates. Although this phenomenon is well known in a male context, limited data are available in female spor...

  • Study Protocol
  • Open Access
3 Citations
2,406 Views
10 Pages

Identifying and Removing Fraudulent Attempts to Enroll in a Human Health Improvement Intervention Trial in Rural Communities

  • Karla L. Hanson,
  • Grace A. Marshall,
  • Meredith L. Graham,
  • Deyaun L. Villarreal,
  • Leah C. Volpe and
  • Rebecca A. Seguin-Fowler

9 November 2024

Using the internet to recruit participants into research trials is effective but can attract high numbers of fraudulent attempts, particularly via social media. We drew upon the previous literature to rigorously identify and remove fraudulent attempt...

  • Article
  • Open Access
745 Views
12 Pages

Relative Age Effect in Olympic Karate: Evidence from Tokyo 2020

  • Sofia Serafini,
  • Simone Ciaccioni,
  • Gabriele Mascherini and
  • Pascal Izzicupo

Background: The Relative Age Effect (RAE) refers to the advantage conferred to athletes born earlier within a selection year. In karate, particularly at the highest level, evidence is lacking. This study aimed to examine the presence of RAE among mal...

  • Article
  • Open Access
1 Citations
779 Views
15 Pages

Born to Win? The Hidden Bias of Birthdates in Spanish Orienteering Talent Selection

  • Javier Montiel-Bonmatí,
  • Javier Marco-Siles and
  • Alberto Ferriz-Valero

17 July 2025

The Relative Age Effect (RAE) refers to the advantage that relatively older athletes within the same age group may have in sports. While this phenomenon has been widely documented in numerous disciplines, its presence in orienteering remains largely...

  • Article
  • Open Access
3 Citations
3,105 Views
15 Pages

Birthplace and Birthdate Effect during Talent Process in Professional Soccer Academy Players

  • Lander Hernandez-Simal,
  • Julio Calleja-González,
  • Alberto Lorenzo Calvo and
  • Maite Aurrekoetxea-Casaus

22 May 2024

The main objective of this study was to detect, from among a set of innate, acquired, and contextual factors, those variables that are ascribed to players ultimately promoted to the professional team of a Spanish league club during the earlier select...

  • Article
  • Open Access
3,777 Views
9 Pages

Relative Age Effect Analysis in the History of the Ballon d’Or (1956–2023)

  • Miguel A. Saavedra-García,
  • Miguel Santiago-Alonso,
  • Helena Vila-Suárez,
  • Antonio Montero-Seoane and
  • Juan J. Fernández-Romero

22 April 2024

Ballon d’Or is the most important individual award in football, and is a significant measure of excellence. From our knowledge, this is the first study that explored the relative age effect (RAE) throughout the history of the Ballon d’Or....

  • Article
  • Open Access
1 Citations
5,492 Views
9 Pages

14 July 2015

A total of 1379 beef bull pictures were surveyed to determine visibility of feet and legs from four American semen company websites. Five different breeds were represented: Angus, Red Angus, Hereford (polled and horned), Simmental, and Charolais. In...

  • Article
  • Open Access
5 Citations
2,883 Views
16 Pages

8 November 2021

The identification of unknown human remains represents an important task in forensic casework. If there are no clues as to the identity of the remains, then the age, sex, and origin are the most important factors to limit the search for a matching pe...

  • Article
  • Open Access
13 Citations
11,025 Views
5 Pages

Environmental exposures, including some that vary seasonally, may play a role in the development of many types of childhood diseases such as cancer. Those observed in children are unique in that the relevant period of exposure is inherently limited o...

  • Study Protocol
  • Open Access
1 Citations
2,680 Views
11 Pages

The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol

  • Darci Neves Santos,
  • Tânia Maria de Araújo,
  • Leticia Marques dos Santos,
  • Hannah Kuper,
  • Rosana Aquino,
  • Ismael Henrique Da Silveira,
  • Samilly Silva Miranda,
  • Marcos Pereira and
  • Guilherme Loureiro Werneck

This article describes the Salvador Primary Care Longitudinal Study of Child Development (CohortDICa). The exposed group was defined by confirmation of Congenital Zika Syndrome (CZS) diagnosed through computed tomography, magnetic resonance or transf...

  • Article
  • Open Access
3 Citations
2,585 Views
18 Pages

30 October 2022

Healthcare is an important medical topic in recent years. In this study, the novelty we propose is the intelligent healthcare system using an inequality-type optimization mathematical model with signal-to-noise ratio (SNR) and wavelet-domain low-freq...

  • Article
  • Open Access
3 Citations
2,174 Views
18 Pages

Variations in External and Internal Intensities and Impact of Maturational Age on Soccer Training Tasks

  • Juan Manuel García-Ceberino,
  • José Manuel Cantonero-Cobos,
  • Cristina Conde and
  • Eduardo José Fernández-Ozcorta

30 August 2024

During peak height velocity, adjusting training intensity is crucial for optimizing performance and minimizing injury risk. This cross-sectional study compares external and internal intensities in different training tasks (analytical tasks, small-sid...

  • Article
  • Open Access
2 Citations
2,960 Views
11 Pages

Disentangling Gender and Relative Age Effects in Women’s and Girls’ Rugby Union

  • Adam L. Kelly,
  • Diogo Coutinho,
  • John M. Radnor,
  • Kate Burke,
  • Donald Barrell,
  • Daniel Jackson and
  • Paolo R. Brustio

Relative age effects (RAEs) within sports refer to the overrepresentation of athletes born earlier in the selection year and the underrepresentation of those born later in the selection year. Research examining RAEs in women’s and girls’...

  • Article
  • Open Access
17 Citations
6,494 Views
25 Pages

Whole-Body 12C Irradiation Transiently Decreases Mouse Hippocampal Dentate Gyrus Proliferation and Immature Neuron Number, but Does Not Change New Neuron Survival Rate

  • Giulia Zanni,
  • Hannah M. Deutsch,
  • Phillip D. Rivera,
  • Hung-Ying Shih,
  • Junie A. LeBlanc,
  • Wellington Z. Amaral,
  • Melanie J. Lucero,
  • Rachel L. Redfield,
  • Matthew J. DeSalle and
  • Amelia J. Eisch
  • + 4 authors

9 October 2018

High-charge and -energy (HZE) particles comprise space radiation and they pose a challenge to astronauts on deep space missions. While exposure to most HZE particles decreases neurogenesis in the hippocampus—a brain structure important in memory—prio...

  • Article
  • Open Access
14 Citations
8,601 Views
8 Pages

9 July 2021

Background: In football, annual age-group categorization leads to relative age effects (RAEs) in talent development. Given such trends, relative age may also associate with market values. This study analyzed the relationship between RAEs and market v...

  • Article
  • Open Access
1 Citations
2,324 Views
12 Pages

12 June 2025

The relative age effect (RAE) refers to the advantage often observed in sports selection processes, where athletes born earlier in the calendar year are favored over those born later. While the RAE has been widely studied in various sports, little is...