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19 Results Found

  • Article
  • Open Access
23 Citations
3,994 Views
10 Pages

Changes in the Choroidal Thickness of Children Wearing MiSight to Control Myopia

  • Francisco Luis Prieto-Garrido,
  • Cesar Villa-Collar,
  • Jose Luis Hernandez-Verdejo,
  • Cristina Alvarez-Peregrina and
  • Alicia Ruiz-Pomeda

1 July 2022

Background: Due to the importance of choroidal thickness in the development of myopia, this study examined the effect of MiSight contact lenses (CLs) on the choroidal thickness of myopic children and the differences between responders and non-respond...

  • Article
  • Open Access
835 Views
10 Pages

Objective: The purpose of this study is to investigate the effect of low-dose atropine and dual-focus MiSight contact lenses on myopia control. Methods: This study included a retrospective review of patients (5–13 years old) started on MiSight...

  • Article
  • Open Access
15 Citations
7,478 Views
10 Pages

Low-Concentration Atropine Monotherapy vs. Combined with MiSight 1 Day Contact Lenses for Myopia Management

  • Nir Erdinest,
  • Naomi London,
  • Itay Lavy,
  • David Landau,
  • Dror Ben Ephraim Noyman,
  • Nadav Levinger and
  • Yair Morad

12 December 2022

Objectives: To assess the decrease in myopia progression and rebound effect using topical low-dose atropine compared to a combined treatment with contact lenses for myopic control. Methods: This retrospective review study included 85 children aged 10...

  • Systematic Review
  • Open Access
10 Citations
6,689 Views
14 Pages

Systematic Review of Myopia Progression after Cessation of Optical Interventions for Myopia Control

  • Yu-Chieh Chiu,
  • Ping-Chiao Tsai,
  • Ssu-Hsien Lee,
  • Jen-Hung Wang and
  • Cheng-Jen Chiu

21 December 2023

Despite high discontinuation rates for myopia optical interventions, limited attention has been given to the potential rebound effects post-discontinuation. This systematic review aims to assess the extent of the rebound effects following the cessati...

  • Article
  • Open Access
5 Citations
3,498 Views
13 Pages

The Influence of Genetics in Myopia Control: A Pilot Study

  • Cristina Alvarez-Peregrina,
  • Miguel Ángel Sánchez-Tena,
  • Clara Martinez-Perez,
  • Catalina Santiago-Dorrego,
  • Thomas Yvert,
  • Cristina Andreu-Vazquez and
  • Cesar Villa-Collar

17 February 2021

Background: Many epidemiological and experimental studies have established that myopia is caused by a complex interaction between common genetic and environmental factors. The objective of this study was to describe and compare the allelic and genoty...

  • Article
  • Open Access
4 Citations
2,181 Views
12 Pages

Could Children’s Myopization Have Been Avoided during the Pandemic Confinement? The Conjunctival Ultraviolet Autofluorescence (CUVAF) Biomarker as an Answer

  • Miriam de la Puente,
  • Cristina Irigoyen-Bañegil,
  • Aura Ortega Claici,
  • Jorge González-Zamora,
  • Valentina Bilbao-Malavé,
  • Patricia Fernandez-Robredo,
  • María Hernández,
  • Jesús Barrio,
  • Alfredo García-Layana and
  • Sergio Recalde

Background: The objective of this study was to evaluate the association of the presence of conjunctival ultraviolet autofluorescence (CUVAF) with the level and progression of myopia and the impact of reduced sunlight exposure during the COVID-19 pand...

  • Article
  • Open Access
2 Citations
1,937 Views
12 Pages

11 August 2023

Hidden corrosion remains a significant problem during aircraft service, primarily because of difficulties in its detection and assessment. The non-destructive D-Sight testing technique is characterized by high sensitivity to this type of damage and i...

  • Article
  • Open Access
57 Citations
6,461 Views
9 Pages

Uptake of MicroRNAs from Exosome-Like Nanovesicles of Edible Plant Juice by Rat Enterocytes

  • Yuko Ito,
  • Kohei Taniguchi,
  • Yuki Kuranaga,
  • Nabil Eid,
  • Yosuke Inomata,
  • Sang-Woong Lee and
  • Kazuhisa Uchiyama

MicroRNAs (miRNAs) are small RNAs present in extracellular vesicles (EVs) that, when transferred to a target cell, affect its biological functions. Plant miRNAs regulate the expression of certain mammalian genes. Here, we characterized EVs in fruit a...

  • Review
  • Open Access
21 Citations
6,560 Views
39 Pages

Dissimilar Appearances Are Deceptive–Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma

  • Lisa Linck-Paulus,
  • Claus Hellerbrand,
  • Anja K. Bosserhoff and
  • Peter Dietrich

2 January 2020

In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by miRNAs—melanoma and hepatocellular carcinoma (HCC). By focusing on common microRNAs and assoc...

  • Article
  • Open Access
1 Citations
2,073 Views
26 Pages

3 November 2022

This study investigates methods for autonomous navigation of a deep-space spacecraft where one-way radiometric and on-board optical information are fused to create a fully informed state estimate. The specific focus is on using filter bank methods (i...

  • Article
  • Open Access
30 Citations
4,200 Views
20 Pages

miRNAs and Genes Involved in the Interplay between Ocular Hypertension and Primary Open-Angle Glaucoma. Oxidative Stress, Inflammation, and Apoptosis Networks

  • Jorge Raga-Cervera,
  • Jose M. Bolarin,
  • Jose M. Millan,
  • Jose J. Garcia-Medina,
  • Laia Pedrola,
  • Javier Abellán-Abenza,
  • Mar Valero-Vello,
  • Silvia M. Sanz-González,
  • José E. O’Connor and
  • Vicente Zanón-Moreno
  • + 4 authors

21 May 2021

Glaucoma has no cure and is a sight-threatening neurodegenerative disease affecting more than 100 million people worldwide, with primary open angle glaucoma (POAG) being the most globally prevalent glaucoma clinical type. Regulation of gene expressio...

  • Article
  • Open Access
62 Citations
6,600 Views
25 Pages

Distinct Exosomal miRNA Profiles from BALF and Lung Tissue of COPD and IPF Patients

  • Gagandeep Kaur,
  • Krishna Prahlad Maremanda,
  • Michael Campos,
  • Hitendra S. Chand,
  • Feng Li,
  • Nikhil Hirani,
  • M. A. Haseeb,
  • Dongmei Li and
  • Irfan Rahman

31 October 2021

Chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are chronic, progressive lung ailments that are characterized by distinct pathologies. Early detection biomarkers and disease mechanisms for these debilitating disea...

  • Article
  • Open Access
31 Citations
4,808 Views
15 Pages

TREM2 Expression and Amyloid-Beta Phagocytosis in Alzheimer’s Disease

  • Francesca La Rosa,
  • Simone Agostini,
  • Federica Piancone,
  • Ivana Marventano,
  • Ambra Hernis,
  • Chiara Fenoglio,
  • Daniela Galimberti,
  • Elio Scarpini,
  • Marina Saresella and
  • Mario Clerici

Alzheimer’s Disease is the most common form of dementia; its key pathological findings include the deposition of extracellular-neurotoxic-plaques composed of amyloid-beta (Ab). AD-pathogenesis involves mechanisms that operate outside the brain,...

  • Article
  • Open Access
6 Citations
3,611 Views
20 Pages

Effects of Co-Culture EBV-miR-BART1-3p on Proliferation and Invasion of Gastric Cancer Cells Based on Exosomes

  • Mengyao Lin,
  • Shun Hu,
  • Tianyi Zhang,
  • Jiezhen Li,
  • Feng Gao,
  • Zhenzhen Zhang,
  • Ke Zheng,
  • Guoping Li,
  • Caihong Ren and
  • Sheng Zhang
  • + 2 authors

19 May 2023

Aim: EBV encodes at least 44 miRNAs involved in immune regulation and disease progression. Exosomes can be used as carriers of EBV-miRNA-BART intercellular transmission and affect the biological behavior of cells. We characterized exosomes and establ...

  • Article
  • Open Access
20 Citations
4,877 Views
12 Pages

20 January 2022

In an urban scenario, GNSS performance is strongly influenced by gross errors in the measurements, usually related to multipath and non-line-of-sight phenomena. The use of RAIM algorithms is a common approach to solve this issue. A significant amount...

  • Article
  • Open Access
40 Citations
5,782 Views
14 Pages

Extracellular Vesicles Secreted by Glioma Stem Cells Are Involved in Radiation Resistance and Glioma Progression

  • Chenkai Ma,
  • Hong P. T. Nguyen,
  • Jordan J. Jones,
  • Stanley S. Stylli,
  • Clarissa A. Whitehead,
  • Lucy Paradiso,
  • Rodney B. Luwor,
  • Zammam Areeb,
  • Eric Hanssen and
  • Andrew P. Morokoff
  • + 3 authors

Glioblastoma is the most aggressive brain tumour with short survival, partly due to resistance to conventional therapy. Glioma stem cells (GSC) are likely to be involved in treatment resistance, by releasing extracellular vesicles (EVs) containing sp...

  • Article
  • Open Access
56 Citations
9,496 Views
19 Pages

Alterations in the Ocular Surface Fungal Microbiome in Fungal Keratitis Patients

  • Gumpili Sai Prashanthi,
  • Rajagopalaboopathi Jayasudha,
  • Sama Kalyana Chakravarthy,
  • Shalem Raj Padakandla,
  • Chinthala Reddy SaiAbhilash,
  • Savitri Sharma,
  • Bhupesh Bagga,
  • Somasheila I. Murthy,
  • Prashant Garg and
  • Sisinthy Shivaji

Keratitis, an inflammatory disease of the eye, when neglected could lead to sight-threatening complications and ultimately blindness. Globally, over a million people are affected by keratitis annually. Keratitis has a microbial etiology and is caused...

  • Article
  • Open Access
4 Citations
5,990 Views
23 Pages

Comprehensive Analysis of Xiaomi Mi 8 GNSS Antenna Performance

  • Mónica Zabala Haro,
  • Ángel Martín Furones,
  • Ana Anquela Julián and
  • María Jesús Jiménez-Martínez

17 April 2024

The interest in precise point positioning techniques using smartphones increased with the launch of the world’s first dual-frequency L1/L5 GNSS smartphone, Xiaomi Mi 8. The smartphone GNSS antenna is low-cost, sensitive to multipath, and limite...

  • Article
  • Open Access
3 Citations
2,253 Views
21 Pages

Bioactive Hydrogel Supplemented with Stromal Cell-Derived Extracellular Vesicles Enhance Wound Healing

  • Matteo Galbiati,
  • Fabio Maiullari,
  • Maria Grazia Ceraolo,
  • Salma Bousselmi,
  • Nicole Fratini,
  • Klajdi Gega,
  • Sandro Recchia,
  • Anna Maria Ferretti,
  • Giovanni Scala and
  • Claudia Bearzi
  • + 3 authors

Background/Objectives: Skin regeneration is a rapidly advancing field with significant implications for regenerative medicine, particularly in treating wounds and burns. This study explores the potential of hydrogels functionalized with fibroblast-de...