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25 Results Found

  • Article
  • Open Access
25 Citations
6,817 Views
8 Pages

9 September 2023

ICD-11 Complex Posttraumatic Stress Disorder (CPTSD) is a relatively new condition; therefore, there is limited available evidence for its treatment. Prior to the recognition of CPTSD as a separate trauma condition, people who met criteria were often...

  • Article
  • Open Access
5 Citations
6,886 Views
12 Pages

Although many studies have differentiated complex posttraumatic stress disorder (CPTSD) from posttraumatic stress disorder (PTSD), few studies have explored the differences in positive adaptation between the two. The present study aimed to determine...

  • Article
  • Open Access
4 Citations
4,571 Views
19 Pages

Determinants of Care Pathways for C-PTSD Patients in French Psychotrauma Centers: A Qualitative Study

  • Germain Salome,
  • Philippe Vignaud,
  • Perrine Galia,
  • Nathalie Prieto and
  • Nicolas Chauliac

In 2018, the International Classification of Diseases (ICD-11) established a novel nosographic category within the stress-specific disorders known as complex post-traumatic stress disorder (C-PTSD). Characterized by distinctive clinical attributes an...

  • Article
  • Open Access
2 Citations
11,322 Views
17 Pages

6 October 2024

Background: Mental healthcare for children and adolescents with a history of childhood abuse constitutes a major public health issue. Indeed, abuse exposes children to severe and complex post-traumatic stress disorder (cPTSD) but also to neurodevelop...

  • Article
  • Open Access
3 Citations
4,033 Views
18 Pages

25 April 2024

Exposure to adverse childhood experiences (ACEs) is related to higher morbidity and mortality among adolescents. The present study analyzed the independent and cumulative effects of ACE exposure on the likelihood of PTSD and a CPSTD diagnosis in Ugan...

  • Case Report
  • Open Access
1 Citations
2,632 Views
7 Pages

22 January 2025

Background and Clinical Significance: Treatment resistant psychiatric disorders affect millions of people across the globe. Ketamine has been employed as a treatment option for those with treatment resistant depression, as well as for chronic pain an...

  • Article
  • Open Access
3 Citations
4,000 Views
16 Pages

Utilization of Mental Health Provision, Epistemic Stance and Comorbid Psychopathology of Individuals with Complex Post-Traumatic Stress Disorders (CPTSD)—Results from a Representative German Observational Study

  • David Riedl,
  • Hanna Kampling,
  • Tobias Nolte,
  • Christina Kirchhoff,
  • Johannes Kruse,
  • Cedric Sachser,
  • Jörg M. Fegert,
  • Harald Gündel,
  • Elmar Brähler and
  • Astrid Lampe
  • + 2 authors

7 May 2024

Background: Complex post-traumatic stress disorder (CPTSD) is a severely debilitating recently added symptom cluster in the International Classification of Diseases (ICD-11). So far, only limited information on mental health treatment-uptake and -sat...

  • Review
  • Open Access
11 Citations
10,783 Views
21 Pages

Understanding Trauma in IPV: Distinguishing Complex PTSD, PTSD, and BPD in Victims and Offenders

  • Erica Pugliese,
  • Federica Visco-Comandini,
  • Carolina Papa,
  • Luciana Ciringione,
  • Lucia Cornacchia,
  • Fabiana Gino,
  • Loreta Cannito,
  • Stefania Fadda and
  • Francesco Mancini

25 August 2024

This work aims to shed light on the differential diagnosis of complex post-traumatic stress disorder (cPTSD), post-traumatic stress disorder (PTSD), and borderline personality disorder (BPD) within the context of intimate partner violence (IPV), whic...

  • Review
  • Open Access
1 Citations
4,585 Views
18 Pages

What Is the Impact of Unemployment as an Adverse Experience? Post-Traumatic Stress Disorder and Complex Post-Traumatic Stress Disorder: A Meta-Analysis

  • Marcelo Nvo-Fernandez,
  • Valentina Miño-Reyes,
  • Carlos Serrano,
  • Hedy Acosta-Antognoni,
  • Fabiola Salas,
  • Claudio Vásquez Wiedeman,
  • Francisco Ahumada-Méndez and
  • Marcelo Leiva-Bianchi

This meta-analysis examined how unemployment, a psychosocial stressor, influences post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD). It specifically explores unemployment as a risk factor for trauma, with emphasis on CPTSD, and investiga...

  • Article
  • Open Access
7 Citations
7,618 Views
9 Pages

The Impact of Complex PTSD on Suicide Risk in Patients with Bipolar Disorder: A Cross-Sectional Study

  • Anna Maria Iazzolino,
  • Marta Valenza,
  • Martina D’Angelo,
  • Grazia Longobardi,
  • Valeria Di Stefano,
  • Giulia Visalli,
  • Luca Steardo,
  • Caterina Scuderi and
  • Luca Steardo

24 January 2024

Background: Patients with bipolar disorder (BD) are more likely than the general population to experience traumatic events, particularly during childhood, and these may predict and be a risk factor for the development of complex PTSD (cPTSD). The pre...

  • Case Report
  • Open Access
1 Citations
7,893 Views
21 Pages

The Body as a Vessel for Trauma: The Clinical Case Study of Aisha

  • Federica Visco-Comandini,
  • Alberto Barbieri,
  • Francesco Mancini and
  • Alessandra Ciolfi

20 January 2025

This case study examined the process of integration of cognitive behavioral therapy (CBT) and sensorimotor psychotherapy (SP) in three-phase trauma treatment with a 32-year-old female Bengali refugee with Complex Post Traumatic Disorder (C-PTSD). The...

  • Article
  • Open Access
3 Citations
2,509 Views
12 Pages

16 October 2023

Evidence suggests that sex differences commonly occur in trauma-related disorders. The current study aims to explore sex differences in complex posttraumatic stress disorder (CPTSD) symptom networks among Chinese young adults with childhood trauma. T...

  • Article
  • Open Access
286 Views
17 Pages

Body Esteem in Women with Complex PTSD: A Comparative Study

  • Rodrigo Ramirez-Rodriguez,
  • Ángel Alberto Puig-Lagunes,
  • Rafael Fernández-Demeneghi,
  • Ana Karina Ceja-Venegas,
  • Yuliana Yessy Gomez-Rutti and
  • Miriam Betzabe Tecamachaltzi-Silvarán

Background: Although trauma can adversely affect body esteem, the specific impact of complex post-traumatic stress disorder (CPTSD) remains underexplored among Mexican women. Objective: This study examined body esteem among trauma-exposed controls an...

  • Article
  • Open Access
3 Citations
4,139 Views
12 Pages

Sleep Disturbances in Panic Disorder with Comorbid Complex PTSD: A Possible Relationship and Different Psychopathology?

  • Elvira Anna Carbone,
  • Giulia Menculini,
  • Renato de Filippis,
  • Martina D’Angelo,
  • Leonardo Zebi and
  • Luca Steardo

27 July 2023

Background: Several studies have shown the possible link between trauma and sleep disturbances, particularly in anxiety disorders. This issue could be because sympathetic hyperarousal is central to both disorders, probably caused by a dysregulation o...

  • Article
  • Open Access
13 Citations
4,565 Views
16 Pages

Offensive Behavior, Striatal Glutamate Metabolites, and Limbic–Hypothalamic–Pituitary–Adrenal Responses to Stress in Chronic Anxiety

  • Enrico Ullmann,
  • George Chrousos,
  • Seth W. Perry,
  • Ma-Li Wong,
  • Julio Licinio,
  • Stefan R. Bornstein,
  • Olga Tseilikman,
  • Maria Komelkova,
  • Maxim S. Lapshin and
  • Rachel Yehuda
  • + 13 authors

9 October 2020

Variations in anxiety-related behavior are associated with individual allostatic set-points in chronically stressed rats. Actively offensive rats with the externalizing indicators of sniffling and climbing the stimulus and material tearing during 10...

  • Article
  • Open Access
18 Citations
4,324 Views
15 Pages

A Rat Model of Post-Traumatic Stress Syndrome Causes Phenotype-Associated Morphological Changes and Hypofunction of the Adrenal Gland

  • Vadim Tseilikman,
  • Maria Komelkova,
  • Marina V. Kondashevskaya,
  • Eugenia Manukhina,
  • H. Fred Downey,
  • Valerii Chereshnev,
  • Margarita Chereshneva,
  • Pavel Platkovskii,
  • Anna Goryacheva and
  • Enrico Ullmann
  • + 9 authors

8 December 2021

Background: Rats exposed to chronic predator scent stress mimic the phenotype of complex post-traumatic stress disorder (PTSD) in humans, including altered adrenal morphology and function. High- and low-anxiety phenotypes have been described in rats...

  • Case Report
  • Open Access
1 Citations
2,755 Views
19 Pages

Treating Complex Trauma in Adolescence: A Case Study of Brief Focal Psychotherapy After Vicarious Gender Violence and Child Abuse

  • Georgina Rosell-Bellot,
  • Eva Izquierdo-Sotorrío,
  • Ana Huertes-del Arco,
  • María Rueda-Extremera and
  • María Elena Brenlla

6 June 2025

This study aims to illustrate the impact of accumulated traumatic experiences in adolescence and to evaluate the potential of brief focal psychotherapy (BFP) as a treatment approach for complex trauma. We present the case of a 14-year-old boy who exp...

  • Article
  • Open Access
3 Citations
7,675 Views
12 Pages

Unraveling the Complexity: Exploring the Intersection of Panic Disorder, Dissociation, and Complex Post-Traumatic Stress Disorder

  • Martina D’Angelo,
  • Marta Valenza,
  • Anna Maria Iazzolino,
  • Grazia Longobardi,
  • Valeria Di Stefano,
  • Elena Lanzara,
  • Giulia Visalli,
  • Luca Steardo,
  • Caterina Scuderi and
  • Luca Steardo

22 February 2024

Background: Patients with panic disorder (PD) may experience increased vulnerability to dissociative and anxious phenomena in the presence of repeated traumatic events, and these may be risk factors for the development of complex post-traumatic stres...

  • Case Report
  • Open Access
7 Citations
8,187 Views
17 Pages

19 December 2023

This study explores the use of real-time heart rate variability (HRV) monitoring as an innovative tool in a psychological intervention program for complex post-traumatic stress disorder (CPTSD). The research focuses on a 25-year-old male subject, pre...

  • Article
  • Open Access
10 Citations
7,587 Views
12 Pages

Exploring the Interplay between Complex Post-Traumatic Stress Disorder and Obsessive–Compulsive Disorder Severity: Implications for Clinical Practice

  • Martina D’Angelo,
  • Marta Valenza,
  • Anna Maria Iazzolino,
  • Grazia Longobardi,
  • Valeria Di Stefano,
  • Giulia Visalli,
  • Luca Steardo,
  • Caterina Scuderi,
  • Mirko Manchia and
  • Luca Steardo

28 February 2024

Background and Objectives: Traumatic events adversely affect the clinical course of obsessive–compulsive disorder (OCD). Our study explores the correlation between prolonged interpersonal trauma and the severity of symptoms related to OCD and a...

  • Feature Paper
  • Review
  • Open Access
1 Citations
2,169 Views
20 Pages

23 May 2025

One of the most problematic situations for the estimated 60 million working donkeys and mules across the world is within the brick kiln environment. In countries such as Egypt, Nepal, India and Pakistan, donkeys and mules carry dried bricks into smal...

  • Case Report
  • Open Access
1,602 Views
9 Pages

Hypersomnia may be classified as primary or secondary, with secondary hypersomnia arising from a variety of underlying causes. Thus, according to ICSD3-TR classification, the diagnosis of idiopathic hypersomnia (IH) is established based on (1) excess...

  • Article
  • Open Access
6 Citations
9,527 Views
12 Pages

27 September 2016

This paper discusses the exclusion of veterans with combat PTSD (CPTSD) from eligibility for the Purple Heart (PH). The main argument is that this exclusion is unjustified and that it strengthens the stigma attached to the traumatized veterans, with...

  • Review
  • Open Access
8 Citations
9,869 Views
26 Pages

Approximately 70% of people will experience a traumatic event in their lifetime, but post-traumatic stress disorder (PTSD) will only develop in 3.9% and complex post-traumatic stress disorder (CPTSD) in 1–8% of the population worldwide, althoug...

  • Article
  • Open Access
2 Citations
6,470 Views
19 Pages

20 August 2025

Background/Objectives: Borderline Personality Disorder (BPD) frequently overlaps with trauma-related conditions, particularly PTSD and Complex PTSD (cPTSD). Adverse Childhood Experiences (ACEs)—especially emotional and sexual abuse—are co...