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19 Results Found

  • Article
  • Open Access
4 Citations
2,255 Views
18 Pages

Isolation of Virulent Leptospira Serogroup Australis Field Strains from Symptomatic Dogs for Canine Leptospiral Vaccine Development

  • Pierre Bergamo,
  • Marine Le Guyader,
  • Marine Hugonnard,
  • Pascale Bourhy,
  • Nathalie Simon-Dufay,
  • Jérôme Bouvet,
  • Jean-Christophe Thibault and
  • Lionel Cupillard

Leptospirosis is a widespread zoonosis caused by spirochaetes belonging to the pathogenic species of Leptospira, which are classified into more than 25 serogroups and 250 serovars. Vaccination can prevent the disease in dogs but offers incomplete eff...

  • Article
  • Open Access
21 Citations
3,616 Views
6 Pages

Identification of Serogroups Australis and Icterohaemorrhagiae in Two Dogs with a Severe Form of Acute Leptospirosis in Italy

  • Andrea Balboni,
  • Silvia Zamagni,
  • Cristina Bertasio,
  • Maria Beatrice Boniotti,
  • Roberta Troìa,
  • Mara Battilani and
  • Francesco Dondi

Leptospirosis is an infectious disease that causes serious illness in dogs. For this reason, epidemiological and clinical studies focusing on disease characterization are widely advocated. The aim of this study was to characterize the leptospires ide...

  • Article
  • Open Access
13 Citations
5,852 Views
14 Pages

Feline Susceptibility to Leptospirosis and Presence of Immunosuppressive Co-Morbidities: First European Report of L. interrogans Serogroup Australis Sequence Type 24 in a Cat and Survey of Leptospira Exposure in Outdoor Cats

  • Elisa Mazzotta,
  • Gabrita De Zan,
  • Monia Cocchi,
  • Maria Beatrice Boniotti,
  • Cristina Bertasio,
  • Tommaso Furlanello,
  • Laura Lucchese,
  • Letizia Ceglie,
  • Laura Bellinati and
  • Alda Natale

Leptospirosis is one of the most widespread zoonotic diseases and can infect both humans and animals worldwide. The role of the cat as a susceptible host and potential environmental reservoir of Leptospira is still not well understood, due to the lac...

  • Article
  • Open Access
1 Citations
2,403 Views
11 Pages

Application of Multilocus Sequence Typing for the Characterization of Leptospira Strains in Malaysia

  • Fairuz Amran,
  • Nurul Atiqah Noor Halim,
  • Ayu Haslin Muhammad,
  • Mohd Khairul Nizam Mohd Khalid,
  • Nur Mukmina Dasiman,
  • Nadia Aqilla Shamsusah,
  • Abdul Khalif Adha Abd Talib,
  • Mohamed Asyraf Noh,
  • Mohammad Ridhuan Mohd Ali and
  • Rohaidah Hashim

Leptospirosis is a common zoonotic disease in tropical and subtropical countries. It is considered an emerging disease in Malaysia and is a notifiable disease. This study was conducted to characterize Malaysian isolates from human, animal and environ...

  • Article
  • Open Access
2 Citations
2,971 Views
12 Pages

Leptospira spp. Antibody Seroprevalence in Stray Dogs and Cats: A Study in Milan, Northern Italy

  • Joel Filipe,
  • Stefania Lauzi,
  • Flavia Bullo,
  • Mario D’Incau,
  • Gabriele Meroni,
  • Piera Anna Martino,
  • Sonia Magistrelli,
  • Maurizio Restelli and
  • Paola Dall’Ara

5 October 2024

Leptospirosis is a widespread zoonosis recognised as a re-emerging infectious disease in both humans and dogs, yet the actual seroprevalence of Leptospira in pets in Italy is relatively unknown. The aim of this study was to evaluate Leptospira antibo...

  • Article
  • Open Access
2 Citations
2,139 Views
12 Pages

1 December 2024

Background: The circulation of Leptospira has been linked to various occupational activities globally. This study investigated the seroprevalence of Leptospira spp. in rodents and livestock (cattle and goats) in three settlements/villages involved in...

  • Article
  • Open Access
7 Citations
3,761 Views
16 Pages

An Assessment and Comparison of the Efficacy of Two Licensed Tetravalent Leptospira Vaccines for Dogs Using an Improved Challenge Model

  • Henricus Leo Bernardus Maria Klaasen,
  • Mark van der Veen,
  • Christina Maria Dorrestein-Spierenburg and
  • Qi Cao

5 September 2022

An objective of the present studies was to compare the protective effects of two European licensed canine tetravalent leptospirosis vaccines, Nobivac L4 and Versican Plus L4. Four similar challenge studies in beagle dogs were performed. In each study...

  • Article
  • Open Access
30 Citations
5,055 Views
23 Pages

Serological Survey and Molecular Typing Reveal New Leptospira Serogroup Pomona Strains among Pigs of Northern Italy

  • Cristina Bertasio,
  • Alice Papetti,
  • Erika Scaltriti,
  • Silvia Tagliabue,
  • Mario D’Incau and
  • Maria Beatrice Boniotti

Swine act as both maintenance and incidental hosts of pathogenic Leptospira spp. Here, a serological test was performed on 131,660 pig sera collected between 2002 and 2017 from 4715 farms in Northern Italy. A positivity rate of 13.05% was determined....

  • Article
  • Open Access
8 Citations
3,006 Views
10 Pages

Leptospira in Slaughtered Fattening Pigs in Southern Italy: Serological Survey and Molecular Typing

  • Giusi Macaluso,
  • Alessandra Torina,
  • Valeria Blanda,
  • Annalisa Guercio,
  • Antonio Lastra,
  • Ilenia Giacchino,
  • Rosalia D’Agostino,
  • Carmela Sciacca,
  • Mario D’Incau and
  • Cristina Bertasio
  • + 1 author

25 February 2022

Leptospirosis is a re-emerging zoonosis of worldwide significance; a wide spectrum of wild and domestic animal species act as natural or accidental hosts. Swine can act as maintenance or accidental hosts of pathogenic Leptospira spp. This study aimed...

  • Brief Report
  • Open Access
5 Citations
1,939 Views
9 Pages

Seroepidemiological Analysis of Canine Leptospira Species Infections in Changchun, China

  • Yue Ding,
  • Wenlong Zhang,
  • Xufeng Xie,
  • Shilei Zhang,
  • Ning Song,
  • Zhanbin Liu and
  • Yongguo Cao

Leptospirosis is a significant worldwide zoonotic infectious disease that infects a wide range of animals and humans. Leptospira will colonize the animal’s urinary and reproductive systems and be excreted with urine, potentially causing a wide...

  • Brief Report
  • Open Access
2 Citations
3,092 Views
9 Pages

Spatial Owner-Dog Seroprevalence of Leptospira spp. Antibodies in Oceanic Islands and Costal Mainland of Southern Brazil

  • Aaronson Ramathan Freitas,
  • Ruana Renostro Delai,
  • Louise Bach Kmetiuk,
  • Raquel Cuba Gaspar,
  • Evelyn Cristine da Silva,
  • Rafaella Martini,
  • Leandro Meneguelli Biondo,
  • Rogério Giuffrida,
  • Ivan Roque de Barros Filho and
  • Vamilton Alvares Santarém
  • + 3 authors

Leptospirosis has been described as a disease neglected worldwide. Affecting humans and animals, the disease is often related to poor environmental conditions such as lack of sanitation and presence of synanthropic rodents. Despite being considered a...

  • Communication
  • Open Access
4 Citations
3,514 Views
9 Pages

Animals Exposed to Leptospira Serogroups Not Included in Bacterins in the United States and Puerto Rico

  • Tammy Anderson,
  • Camila Hamond,
  • Andréa Haluch,
  • Kari Toot,
  • Jarlath E. Nally,
  • Karen LeCount and
  • Linda K. Schlater

Leptospirosis is a worldwide zoonotic disease. Pathogenic leptospires colonize the renal tubules and genital tract of animals and are excreted via urine. Transmission occurs via direct contact or through contaminated water or soil. The microscopic ag...

  • Article
  • Open Access
9 Citations
6,364 Views
10 Pages

Exposure and Carriage of Pathogenic Leptospira in Livestock in St. Croix, U.S. Virgin Islands

  • Hannah M. Cranford,
  • Marissa Taylor,
  • Andrew Springer Browne,
  • David P. Alt,
  • Tammy Anderson,
  • Camila Hamond,
  • Richard L. Hornsby,
  • Karen LeCount,
  • Linda Schlater and
  • Tod Stuber
  • + 5 authors

From 2019–2020, the Virgin Islands Department of Health (VIDOH) investigated potential animal reservoirs of Leptospira spp., the pathogenic bacteria that cause leptospirosis. We examined Leptospira exposure and carriage in livestock on the island of...

  • Article
  • Open Access
1 Citations
3,549 Views
12 Pages

Seroprevalence of Equine Leptospirosis in the State of Goiás, Brazil

  • Tatiana Nunes de Azevedo Romanowski,
  • Ricardo Augusto Dias,
  • Marcos Bryan Heinemann,
  • Stephani Félix Carvalho,
  • Tamires Ataides Silva,
  • Andressa da Silva Martins,
  • Geovanna Domingues da Cunha Caetano,
  • Álvaro Ferreira Júnior,
  • Jandra Pacheco dos Santos and
  • Ana Carolina Borsanelli

25 September 2023

Leptospirosis, caused by Leptospira, is a zoonotic disease that, in horses, is linked to abortions, uveitis, and sporadic occurrences of liver and kidney disease, often resulting in significant economic losses for farmers. Research on the prevalence...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,065 Views
18 Pages

Molecular Detection of Viral and Bacterial Pathogens in Red Foxes (Vulpes vulpes) from Italy

  • Martina Magliocca,
  • Roberta Taddei,
  • Lorenza Urbani,
  • Cristina Bertasio,
  • Veronica Facile,
  • Laura Gallina,
  • Maria Sampieri,
  • Gianluca Rugna,
  • Silva Rubini and
  • Giulia Maioli
  • + 3 authors

3 July 2024

Animals, including wildlife, are part of One-Health concept since many infectious diseases can affect both humans and animals. In this study, 126 red foxes (Vulpes vulpes) from Northern Italy in 2022–2023 were tested by molecular assays for Pro...

  • Article
  • Open Access
30 Citations
4,522 Views
16 Pages

Leptospira Survey in Wild Boar (Sus scrofa) Hunted in Tuscany, Central Italy

  • Giovanni Cilia,
  • Fabrizio Bertelloni,
  • Marta Angelini,
  • Domenico Cerri and
  • Filippo Fratini

Leptospirosis is a re-emerging, worldwide zoonosis, and wild boar (Sus scrofa) are involved in its epidemiology as the reservoir. The aim of this study was to investigate the prevalence of Leptospira with serological, bacteriological, and molecular a...

  • Article
  • Open Access
35 Citations
5,750 Views
20 Pages

Detection of New Leptospira Genotypes Infecting Symptomatic Dogs: Is a New Vaccine Formulation Needed?

  • Cristina Bertasio,
  • Maria Beatrice Boniotti,
  • Laura Lucchese,
  • Letizia Ceglie,
  • Laura Bellinati,
  • Matteo Mazzucato,
  • Tommaso Furlanello,
  • Mario D’Incau and
  • Alda Natale

Leptospirosis in dogs has been largely described worldwide, and epidemiological studies have been mainly based on serological data. This study aims to detect and genotype leptospires affecting symptomatic dogs in Northeast Italy between 2013 and 2019...

  • Article
  • Open Access
3 Citations
2,497 Views
10 Pages

Leptospira interrogans Sensu Lato in Wild Small Mammals in Three Moravian Localities of the Czech Republic

  • Alena Žákovská,
  • František Treml,
  • Helena Nejezchlebová,
  • Jiří Nepeřený,
  • Marie Budíková and
  • Eva Bártová

Leptospirosis is a widespread zoonosis, affecting humans, domestic animals and wildlife, with small mammals as a reservoir of this infection. In recent years, this disease has been re-emerging and affects approximately 1 million people all over the w...

  • Article
  • Open Access
21 Citations
2,817 Views
14 Pages

Synanthropic and Wild Animals as Sentinels of Zoonotic Agents: A Study of Leptospira Genotypes Circulating in Northeastern Italy

  • Elisa Mazzotta,
  • Laura Bellinati,
  • Cristina Bertasio,
  • Maria Beatrice Boniotti,
  • Laura Lucchese,
  • Letizia Ceglie,
  • Federico Martignago,
  • Stefania Leopardi and
  • Alda Natale

Leptospirosis is an infectious disease widely reported in veterinary practice and a worldwide zoonosis. In Northeastern Italy, different serogroups and genotypes of Leptospira have been described in ill dogs, the most commonly detected being Icteroha...