Skip to Content

11 Results Found

  • Article
  • Open Access
2 Citations
1,956 Views
20 Pages

2 December 2024

Recently, 4-(pyrrol-1-yl)pyridine has been found to act as a supramolecular chemodosimeter, sensing nitrite ions in an aqueous solution with naked eye detection and a low limit of detection of 0.330 ppm. This work explores the anion-sensing propertie...

  • Communication
  • Open Access
6 Citations
5,747 Views
8 Pages

28 June 2018

We synthesized 2-[2-methyl-5-phenyl-1-(3,4,5-trimethoxyphenyl)-1H-pyrrol-3-yl]-2-oxo-N-(pyridin-4-yl) acetamide 4 as a novel compound derived from the indibulin and combretastatin scaffolds, which are known anti-mitotic agents, using a multistep reac...

(This article belongs to the Special Issue Heterocycles)
  • Article
  • Open Access
8 Citations
3,485 Views
12 Pages

Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP

  • Anastasia Khandazhinskaya,
  • Ilja Fateev,
  • Barbara Eletskaya,
  • Anna Maslova and ,
  • Irina Konstantinova,
  • Katherine Seley-Radtke,
  • Sergey Kochetkov and
  • Elena Matyugina
  • + 3 authors+ 0 author

17 January 2023

The great interest in studying the structure of human purine nucleoside phosphorylase (hPNP) and the continued search for effective inhibitors is due to the importance of the enzyme as a target in the therapy of T-cell proliferative diseases. In addi...

(This article belongs to the Special Issue Enzyme Inhibitors: Design, Synthesis and Biological Evaluation)
  • Article
  • Open Access
4 Citations
7,652 Views
17 Pages

Pyrrole-Pyridine and Pyrrole-Naphthyridine Hosts for Anion Recognition

  • M. Angeles García,
  • M. Angeles Farrán,
  • Dolores Santa María,
  • Rosa M. Claramunt and ,
  • M. Carmen Torralba,
  • M. Rosario Torres,
  • Carlos Jaime and
  • José Elguero
  • + 3 authors+ 0 author

27 May 2015

The association constants of the complexes formed by two hosts containing pyrrole, amide and azine (pyridine and 1,8-naphthyridine) groups and six guests, all monoanions (Cl−, CH3CO2−, NO3−, H2PO4−, BF4−, PF6−), have been determined using NMR titrati...

  • Review
  • Open Access
9 Citations
4,860 Views
21 Pages

Recent Progress on Synthesis of N,N′-Chelate Organoboron Derivatives

  • Tianbao Yang,
  • Niu Tang,
  • Qizhong Wan,
  • Shuang-Feng Yin and
  • Renhua Qiu

N,N′-chelate organoboron compounds have been successfully applied in bioimaging, organic light-emitting diodes (OLEDs), functional polymer, photocatalyst, electroluminescent (EL) devices, and other science and technology areas. However, the concise a...

(This article belongs to the Special Issue Synthesis and Application of Organoboron Derivatives)
  • Article
  • Open Access
6 Citations
2,364 Views
11 Pages

18 July 2023

Acyl(imidoyl)ketenes are highly reactive heterocumulenes that enable diversity-oriented synthesis of various drug-like heterocycles. Such ketenes, bearing heterocyclic substituents, afford angularly fused pyridin-2(1H)-ones in their [4+2]-cyclodimeri...

(This article belongs to the Special Issue Chemistry of Nitrogen Heterocyclic Compounds)
  • Article
  • Open Access
35 Citations
6,343 Views
20 Pages

Synthesis of Novel Tritopic Hydrazone Ligands: Spectroscopy, Biological Activity, DFT, and Molecular Docking Studies

  • Sharmin Akther Rupa,
  • Md. Rassel Moni,
  • Md. Abdul Majed Patwary,
  • Md. Mayez Mahmud and ,
  • Md. Aminul Haque,
  • Jamal Uddin and
  • S. M. Tareque Abedin
  • + 2 authors+ 0 author

Polytopic organic ligands with hydrazone moiety are at the forefront of new drug research among many others due to their unique and versatile functionality and ease of strategic ligand design. Quantum chemical calculations of these polyfunctional lig...

(This article belongs to the Topic Novel Antimicrobial Agents: Discovery, Design and New Therapeutic Strategies)
  • Article
  • Open Access
10 Citations
3,252 Views
16 Pages

An Investigation of the Thermal Transitions and Physical Properties of Semiconducting PDPP4T:PDBPyBT Blend Films

  • Barbara Hajduk,
  • Paweł Jarka,
  • Tomasz Tański,
  • Henryk Bednarski and ,
  • Henryk Janeczek,
  • Paweł Gnida and
  • Mateusz Fijalkowski
  • + 2 authors+ 0 author

25 November 2022

This work focuses on the study of thermal and physical properties of thin polymer films based on mixtures of semiconductor polymers. The materials selected for research were poly [2,5-bis(2-octyldodecyl)-pyrrolo [3,4-c]pyrrole-1,4(2H,5H)-dione-3,6-di...

(This article belongs to the Section Polymeric Materials)
  • Article
  • Open Access
45 Citations
10,659 Views
10 Pages

A Ratiometric Fluorescent Sensor for Cd2+ Based on Internal Charge Transfer

  • Dandan Cheng,
  • Xingliang Liu,
  • Yadian Xie,
  • Haitang Lv and ,
  • Zhaoqian Wang,
  • Hongzhi Yang,
  • Aixia Han,
  • Xiaomei Yang and
  • Ling Zang
  • + 4 authors+ 0 author

2 November 2017

This work reports on a novel fluorescent sensor 1 for Cd2+ ion based on the fluorophore of tetramethyl substituted bis(difluoroboron)-1,2-bis[(1H-pyrrol-2-yl)methylene]hydrazine (Me4BOPHY), which is modified with an electron donor moiety of N,N-bis(p...

(This article belongs to the Special Issue Fluorescent Probes and Sensors)
  • Article
  • Open Access
4 Citations
3,565 Views
23 Pages

11 June 2021

Two novel, pyridinone-based chelating ligands containing separated (O,O) and (Namino,Nhet) chelating sets (Namino = secondary amine; Nhet = pyrrole N for H(L3) (1-(3-(((1H-pyrrole-2-yl)methyl)-amino)propyl)-3-hydroxy-2-methylpyridin-4(1H)-one) or pyr...

(This article belongs to the Section Medicinal Chemistry)
  • Article
  • Open Access
6 Citations
2,798 Views
15 Pages

The Valence and Spin State Tuning of Iron(II/III) Porphyrazines with Bulky Pyrrolyl Periphery in Solution and Solid State

  • Tomasz Koczorowski,
  • Wojciech Szczolko,
  • Pawel Bakun,
  • Barbara Wicher and ,
  • Lukasz Sobotta,
  • Maria Gdaniec,
  • Anna Teubert,
  • Jadwiga Mielcarek,
  • Ewa Tykarska and
  • Tomasz Goslinski
  • + 7 authors+ 2 authors

13 November 2022

Iron(III) porphyrazines containing peripheral 2,5-dimethyl-, 2-methyl-5-phenyl-, and 2,3,5-triphenyl-1H-pyrrol-1-yl substituents were synthesized and subjected to physicochemical characterization. This was accomplished by high-resolution mass spectro...