HIV and Viral Hepatitis Co-Infection
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".
Deadline for manuscript submissions: closed (31 March 2026) | Viewed by 3933
Special Issue Editors
Interests: infectious diseases; clinical virology; HIV infection; HIV persistence; immune responses to viral infections
Special Issues, Collections and Topics in MDPI journals
Interests: HIV infection and pathogenesis; HIV-1–host interaction; HCV/HIV co-infection
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Co-infections with hepatitis viruses A to E and human immunodeficiency virus (HIV) present significant public health challenges worldwide and contribute to a significant amount of morbidity and mortality among people living with HIV (PLWH). The management of these co-infections normally includes the use of multiple antiviral and antiretroviral drugs which may interact, limiting therapeutic efficacy or increasing toxicities. Hepatitis A (HAV) and hepatitis E (HEV) viruses are oro-fecal transmissible diseases and mostly produce acute self-limited episodes, but the changing demographic outbreaks among vulnerable populations have contributed to substantial increases in the reported cases of these co-infections in PLWH. Furthermore, the immunosuppression derived from HIV infection can modify the immune response to HAV and HEV infections, causing acute liver dysfunction or development into a chronic infection. Chronic hepatitis B (HBV), C (HCV), and D (HDV) are frequent in PLWH as these viruses share a similar transmission route. HBV vaccination results in protective seroconversion, but it may remain suboptimal in PLWH; therefore, new strategies warrant further consideration. Progression to liver cirrhosis, increased hepatic decompensation, and the development of hepatocellular carcinoma are mostly related to HCV. Although direct acting antivirals can now achieve sustained virological response in nearly almost co-infected individuals, further evidence is needed on the subsequent resolution of liver inflammation and systemic immune activation, as well as the latent HIV reservoir in PLWH.
For this Special Issue, research articles, review articles, as well as short communications are welcome to be submitted to provide novel insights into the evolving epidemiology, clinical aspects, and new preventive and therapeutic approaches of HIV and viral hepatitis co-infections for the better management and care of PLWH.
Dr. Sonia Moretti
Dr. Ivan Schietroma
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- HIV
- hepatitis A
- hepatitis B
- hepatitis C
- hepatitis delta
- hepatitis E
- co-infection
- antiviral therapy
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