Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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West Nile Virus 2025–2026
edited by Orsolya Korbacska-Kutasi and Gábor Kemenesi
submission deadline 31 Mar 2027 | 1 articles | Viewed by 890 | Submission Open
Keywords: West Nile virus; epidemiology; surveillance; biology; evolution; pathogenesis; vaccine development; antiviral therapies
(This special issue belongs to the Section Animal Viruses)
Crimean-Congo Hemorrhagic Fever Virus (CCHFV)
edited by
submission deadline 31 Mar 2027 | Viewed by 675 | Submission Open
Keywords: basic sciences; social sciences; epidemiology; climate studies; clinical studies; diagnostics; serology; molecular detection; entomology; antivirals; vaccines; infection control; nosocomial; transmission; pathogenesis; virulence; taxonomy; genomics
(This special issue belongs to the Section Animal Viruses)
Viral Pneumonia: Recent Advances and Prospects
edited by
submission deadline 31 Mar 2027 | Viewed by 527 | Submission Open
Keywords: viral pneumonia; viral lung infections; respiratory viruses; influenza viruses; respiratory syncytial virus (RSV); coronaviruses (such as SARS-CoV-2); viral persistence; molecular mechanisms; host immune responses; innate and adaptive immunity; immune–metabolic interactions; alveolar regeneration; dysregulated inflammation; epithelial and endothelial repair mechanisms; single-cell omics; organoid models; spatial profiling
(This special issue belongs to the Section General Virology)
New Advances in Small Ruminant Lentiviruses: Genetic Variability, Diagnostic Challenges, and Control Strategies
edited by and
submission deadline 31 Mar 2027 | Viewed by 302 | Submission Open
Keywords: caprine arthritis encephalitis virus (CAEV); cross-species transmission; control and Eradication program; genetic variability; Maedi-Visna virus (MVV); molecular diagnosis; pathology; serological assays; small ruminant lentiviruses (SRLV); wildlife reservoirs
(This special issue belongs to the Section Animal Viruses)
Iridoviruses, 3rd Edition submission deadline 31 Mar 2027 | Viewed by 293 | Submission Open
Keywords: iridovirus; viral immune evasion; anti-viral immune responses; viral vaccine; viral pathogenesis; viral epidemiology
(This special issue belongs to the Section Animal Viruses)
Virioplankton and Climate Change
edited by
submission deadline 31 Mar 2027 | Viewed by 253 | Submission Open
Keywords: viruses; climate change; bacteriophages; viral shunt; bacteria; picophytoplankton
(This special issue belongs to the Section Bacterial Viruses)
Nasal Immunity Against Virus Infection
edited by
submission deadline 31 Mar 2027 | Viewed by 251 | Submission Open
Keywords: virus–host; viral life cycle; viral replication; imaging; respiratory viruses; nasal immunology; type-I interferon; type-III interferon; proinflammatory cytokines; age; viral load
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Human T Cell Leukemia Virus
edited by
submission deadline 31 Mar 2027 | Viewed by 176 | Submission Open
Keywords: infection prevention; vaccines; anti-viral drugs to prevent infection; measures against prejudice and discrimination; public health initiatives; risk evaluation by biomarkers; early therapeutic intervention; new treatment strategies
(This special issue belongs to the Section Human Virology and Viral Diseases)
Druggable Targets for Antiviral Intervention
edited by
submission deadline 31 Mar 2027 | Viewed by 132 | Submission Open
Keywords: host–virus interaction; antiviral development; immunometabolism; broad-spectrum
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Molecular Mechanisms and Structural Biology of High-Pathogenicity RNA Viruses submission deadline 31 Mar 2027 | Viewed by 130 | Submission Open
Keywords: high-pathogenicity RNA viruses; structural virology; virus–host interactions; viral replication complexes; intrinsically disordered proteins; cryo-electron microscopy; immune evasion mechanisms; viral protein structure; phase separation in viral infection; antiviral target discovery
(This special issue belongs to the Section General Virology)
Oncogenic Viruses in Animals and Zoonotic Risks
edited by and María Carolina Ceriani
submission deadline 31 Mar 2027 | Viewed by 93 | Submission Open
Keywords: zoonotic viruses; viral oncogenenic mechanisms; cross-species transmission; retroviruses
(This special issue belongs to the Section Animal Viruses)
Advances in Arbovirus and Respiratory Virus Research: Pathogenesis, Immune Responses and Antiviral Molecular Targets submission deadline 31 Mar 2027 | Viewed by 84 | Submission Open
Keywords: arboviruses; respiratory viruses; viral pathogenesis; host immune responses; innate immunity; adaptive immunity; viral immune evasion; cytokine storm; interferon response; viral replication; viral transmission; immunopathology; neutralizing antibodies; host–virus interactions; antivirals; antiviral screening strategies; therapeutic targets
(This special issue belongs to the Section Animal Viruses)
The Role of Viral Vectors in Biological and Medical Research
edited by
submission deadline 31 Mar 2027 | Viewed by 62 | Submission Open
Keywords: cell and gene therapy; viral vector engineering; adeno-associated virus; lentivirus; herpes simplex virus; CRISPR delivery; oncolytic viruses; neural circuit tracing; safety and efficacy evaluation; vaccine development
(This special issue belongs to the Section Human Virology and Viral Diseases)
Epidemiology, Evolution, Pathogenicity and Antiviral Strategies of Animal Coronaviruses
edited by and
submission deadline 31 Mar 2027 | Viewed by 34 | Submission Open
Keywords: animal coronavirus; epidemiology; evolution; pathogenicity; antiviral; cross-species transmission; vaccine development; virus–host interaction; zoonotic risk; livestock disease
(This special issue belongs to the Section Animal Viruses)
HSV-2 Pathogenesis and Host Defense Mechanisms
edited by
submission deadline 31 Mar 2027 | Viewed by 33 | Submission Open
Keywords: HSV-2; genital herpes; innate immunity; adapt immunity; immune evasion; latency; pathogenesis; translational research
(This special issue belongs to the Section Human Virology and Viral Diseases)
Severe Fever with Thrombocytopenia Syndrome Virus 2027
edited by Masayuki Saijo
submission deadline 31 Mar 2027 | Viewed by 22 | Submission Open
Keywords: SFTS; SFTSV; emerging viral infections; Bandavirus dabieense
(This special issue belongs to the Section Human Virology and Viral Diseases)
Molecular Virus–Insect Interactions, 3rd Edition
edited by Li-Long Pan and Wen-Ze He
submission deadline 31 Mar 2027 | Viewed by 16 | Submission Open
Keywords: plant virus-insect vector interactions; virus transmission; entomopathogenic virus-insect host interactions; insect-specific viruses; induction and suppression of immune responses
(This special issue belongs to the Section Invertebrate Viruses)
Early Diagnosis and Surveillance of Transboundary and Emerging Viral Diseases of Animals, 3rd Edition submission deadline 31 Mar 2027 | Viewed by 12 | Submission Open
Keywords: diagnostics; surveillance; transboundary; emerging; animal diseases; virus; detection; validation; novel; sample types; alternative
(This special issue belongs to the Section Animal Viruses)
HIV Reservoirs, Latency, and the Factors Responsible (2nd Edition)
edited by Yuyang Tang and
submission deadline 1 Apr 2027 | Viewed by 126 | Submission Open
Keywords: HIV; reservoirs; HIV latency; persistence; HIV eradication; HIV cure; HIV vaccines
(This special issue belongs to the Section Human Virology and Viral Diseases)
The Interplay Between Viral Infections and Autoimmune Diseases
edited by
submission deadline 30 Apr 2027 | 2 articles | Viewed by 3643 | Submission Open
Keywords: viral infections; autoimmune diseases; molecular mimicry; epitope spreading; persistent antigen & tissue‐specific antiviral responses; biomarkers & precision stratification; vaccine-related immune dynamics; single-cell & spatial omics; post-viral syndromes; immune repertoire; immune-repertoire alteration syndrome
(This special issue belongs to the Section Human Virology and Viral Diseases)
Advances in Parapoxvirus Research: From Veterinary Infections to Public Health Implications
edited by
submission deadline 30 Apr 2027 | 1 articles | Viewed by 1679 | Submission Open
Keywords: parapoxviruses; zoonotic implications; diagnostic innovation; veterinary infections; molecular epidemiology; genomic surveillance
(This special issue belongs to the Section Animal Viruses)
Recent Advances in Antiviral Natural Products, 2nd Edition submission deadline 30 Apr 2027 | 1 articles | Viewed by 1536 | Submission Open
Keywords: virus; antiviral; natural product; antimicrobial peptides; drug delivery; infectious disease
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Antiviral Agents and Peptides: Discovery, Mechanisms, and Therapeutic Applications
edited by
submission deadline 30 Apr 2027 | 1 articles | Viewed by 1003 | Submission Open
Keywords: antiviral agents; antiviral peptides (AVPs); drug discovery; drug resistance; peptide engineering; mechanisms of antiviral action; structure–activity relationship (SAR); high-throughput screening; AI-assisted design
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Emerging and Re-Emerging Viral Diseases of Veterinary and One Health Importance: Innovations in Veterinary Vaccinology
edited by Gema Lorenzo and
submission deadline 30 Apr 2027 | 1 articles | Viewed by 730 | Submission Open
Keywords: one health; antiviral strategies; veterinary vaccines; ecology; evolution; zoonotic viral pathogens
(This special issue belongs to the Section Animal Viruses)
Advances in Viral Integration: Mechanisms, Targeting, Reservoirs and Therapeutics
edited by
submission deadline 30 Apr 2027 | Viewed by 311 | Submission Open
Keywords: viral integration; integration site selection; chromatin topology; anatomical reservoir; latent provirus; clonal expansion; insertional mutagenesis; gene therapy vector; integrase/co-factor; emerging virus integration
(This special issue belongs to the Section General Virology)
Spectroscopic Advances in Virology: Technique Development and Applications to Viral Structure and Function
edited by
submission deadline 30 Apr 2027 | Viewed by 152 | Submission Open
Keywords: viral dynamics; structural virology; biophysical methods; nuclear magnetic resonance; fluorescence spectroscopy; electron paramagnetic resonance; virus–host interaction; antiviral design
(This special issue belongs to the Section General Virology)
Innate and Mucosal Immunity Against Viral Infections
edited by
submission deadline 30 Apr 2027 | Viewed by 111 | Submission Open
Keywords: viral infection; innate immunity; mucosal immunity; adjuvant; immune escape; mucosal barrier; innate signaling pathway; immunopathogenesis; viral immune defense
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Phage Cocktails: Promising Approaches Against Infections, 2nd Edition
edited by Jin Woo Jun
submission deadline 30 Apr 2027 | Viewed by 49 | Submission Open
Keywords: phage cocktail; phage therapy; prophylaxis; infectious diseases; veterinary medicine; agriculture; food industry; zoonoses
(This special issue belongs to the Section Bacterial Viruses)
AAV Vector Technology Development submission deadline 30 Apr 2027 | Viewed by 30 | Submission Open
Keywords: AAV; adeno-associated virus; capsid; viral vector manufacturing; machine learning; molecular evolution; vector redosing; gene editing; targeted delivery; vector engineering
(This special issue belongs to the Section General Virology)
Molecular and Serology Detection, Antibody Response and Epidemiology of Emerging and Re‑Emerging Viral Pathogens
edited by
submission deadline 30 Apr 2027 | Viewed by 25 | Submission Open
Keywords: emerging viral pathogens; hemorrhagic viruses; molecular and serologic diagnostics; antibody response and immunity; epidemiology and surveillance; outbreak investigation; correlates of protection; re‑emerging infections
(This special issue belongs to the Section General Virology)
Viral Hepatitis Elimination 2030
edited by
submission deadline 30 Apr 2027 | Viewed by 20 | Submission Open
Keywords: viral hepatitis; HBV; HCV; HDV; hepatitis elimination
(This special issue belongs to the Section Human Virology and Viral Diseases)
Viral Genetic Variability and Its Role in Assessing Infectious Diseases submission deadline 6 May 2027 | 2 articles | Viewed by 3908 | Submission Open
Keywords: viral genetic diversity; infectious diseases; viral evolution; host adaptation; next-generation sequencing; pathogenicity; immune evasion; viral surveillance; bioinformatics; genetic variability; phylogeny; phylodynamics
(This special issue belongs to the Section General Virology)
Influenza B Virus: From Infection to Prevention
edited by Saira Hussain
submission deadline 30 May 2027 | 1 articles | Viewed by 1994 | Submission Open
Keywords: influenza B viruses; epidemiology; evolution; pathogenesis; immunity; vaccine; antivirals
(This special issue belongs to the Section Animal Viruses)
Viruses in Extreme Environments
edited by Julian Tang and Tze Ping Loh
submission deadline 31 May 2027 | 3 articles | Viewed by 3123 | Submission Open
Keywords: extreme cold ; extreme heat ; extreme pressure ; microgravity ; radiation ; space ; virus survival
(This special issue belongs to the Section General Virology)
CRISPR/Cas-Mediated Genome Editing in Viral Research
edited by
submission deadline 31 May 2027 | 1 articles | Viewed by 1670 | Submission Open
Keywords: CRISPR–Cas systems; viral genome engineering; antiviral gene therapy; host factor discovery (proviral and antiviral); CRISPR-based diagnostics
(This special issue belongs to the Section General Virology)
Virus–Host Protein Interactions, 2nd Edition
edited by
submission deadline 31 May 2027 | Viewed by 212 | Submission Open
Keywords: virus–host interactions; protein–protein interactions; viral proteins; antiviral drug discovery; protein target inhibitors
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Highly Virulent Viruses: From Pathogenesis to Therapeutics
edited by Lorenzo Subissi and M. Kariuki Njenga
submission deadline 31 May 2027 | Viewed by 199 | Submission Open
Keywords: highly virulent viruses; molecular pathogenesis; host–virus interactions; medical countermeasures
(This special issue belongs to the Section General Virology)
Viral Capsids: Structural and Functional Implications
edited by
submission deadline 31 May 2027 | Viewed by 176 | Submission Open
Keywords: viral capsid assembly and disassembly; structural virology; capsid–host interactions; viral genome packaging and uncoating; antiviral targets and therapeutics; vaccine development and neutralizing antibodies; capsid maturation and dynamics
(This special issue belongs to the Section General Virology)
Advances in Diagnostic Testing and Surveillance of Emerging Viral Pathogens submission deadline 31 May 2027 | Viewed by 112 | Submission Open
Keywords: virus diagnostics; surveillance; evolutionary dynamics
(This special issue belongs to the Section General Virology)
Omics Research on HIV: From Pathogenesis to Treatment
edited by
submission deadline 31 May 2027 | Viewed by 40 | Submission Open
Keywords: HIV pathogenesis; antiretroviral therapy and strategies; omics and multi-omics approaches; metagenomics; machine learning; single-cell sequencing; spatial transcriptomics; epitranscriptomics; metabolomics; bioinformatics
(This special issue belongs to the Section Human Virology and Viral Diseases)
Novel Drugs and Therapeutic Strategies for Herpesviruses
edited by Ravit Arav-Boger
submission deadline 31 May 2027 | Submission Open
Keywords: herpesviruses; antiviral drug discovery; small-molecule antivirals; host-directed therapy; drug resistance mechanisms; immunotherapies and vaccines; drug repurposing
(This special issue belongs to the Section Human Virology and Viral Diseases)
Emerging and Re-Emerging Neuroinvasive Arboviruses
edited by , and Mylena R. Pereira
submission deadline 16 Jun 2027 | 2 articles | Viewed by 3025 | Submission Open
Keywords: arbovirus; innate immune response; adaptive immune response; epidemiology; diagnosis; prevention; vaccine; animal model; pathogenesis; viral evolution; in vitro; in vivo
(This special issue belongs to the Section Animal Viruses)
HIV Infection, Latency, Pathogenesis and Associated Comorbidities, Including Cancer and Inflammation in the Context of Drugs of Abuse and ART
edited by
submission deadline 30 Jun 2027 | Viewed by 316 | Submission Open
Keywords: HIV infection; HIV transcription and latency; HIV, ART and drugs of abuse associated comorbidities in people living with HIV (PLWH); HIV, ART and drugs of abuse associated cancer; HIV, ART and drugs of abuse associated inflammation and aging
(This special issue belongs to the Section Human Virology and Viral Diseases)
Rational Antiviral Therapy: Targeting Viral and Host Determinants for Optimized Treatment submission deadline 30 Jun 2027 | Viewed by 131 | Submission Open
Keywords: precision antiviral therapy; virus–host interactions; host-directed antivirals; antiviral resistance mechanisms; targeted antiviral delivery; omics-driven antiviral strategies
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Advances in the Antigenic Detection of Sylvatic Arbovirus Transmission
edited by Ricardo Gonçalves
submission deadline 30 Jun 2027 | Viewed by 58 | Submission Open
Keywords: zoonotic spillover; antigenic detection; one health surveillance; viral ecology; emerging pathogens
(This special issue belongs to the Section Animal Viruses)
Rodent- and Bat-Borne Viruses: Ecology, Surveillance, and Zoonotic Risk
edited by Olga Suarez and María Belén Pisano
submission deadline 16 Jul 2027 | Viewed by 18 | Submission Open
Keywords: zoonotic viruses; rodents; bats; reservoir ecology; One Health; epidemiological surveillance; spillover risk; South America
(This special issue belongs to the Section Animal Viruses)
Interaction Between Influenza Virus and Host Cell
edited by
submission deadline 31 Jul 2027 | 3 articles | Viewed by 7513 | Submission Open
Keywords: influenza virus; virus-–host interaction; restriction factor; host species barrier; pandemic; pathogenicity; zoonosis; cell culture
(This special issue belongs to the Section Animal Viruses)
Phage Evolution: Taxonomy, Origins, and Diversity
edited by and
submission deadline 31 Jul 2027 | 2 articles | Viewed by 2428 | Submission Open
Keywords: phage taxonomy and phylogeny; origins and evolution of phage genes and genomes; phage-host coevolution; phage diversity and ecology; artificial evolution of phages; computational and bioinformatic approaches to phage evolution
(This special issue belongs to the Section Bacterial Viruses)
Phage: Biocontrol and Biosafety
edited by Ran Wang and Tao He
submission deadline 31 Jul 2027 | Viewed by 351 | Submission Open
Keywords: phage–host interaction; biocontrol and biosafety; antimicrobial resistance; pharmacokinetics/pharmacodynamics of phage; phage and immunity; phage safety assessment; regulatory frameworks
(This special issue belongs to the Section Bacterial Viruses)
Structure, Function, and Inhibition of HIV Proteins: Advances in Therapeutic Targets and Drug Discovery submission deadline 31 Jul 2027 | Viewed by 274 | Submission Open
Keywords: HIV; AIDS; HIV proteins; protein structure and function; enzymatic mechanisms; therapeutic targets; drug discovery; protein inhibition; structure-based drug design; antiretroviral therapy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
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