Special Issues

Viruses publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microscopy Methods for Virus Research, 2nd Edition
edited by Krishanu Ray
submission deadline 31 Dec 2026 | Viewed by 189 | Submission Open
Keywords: viruses; fluorescence imaging; single-molecule imaging; super-resolution imaging; intra-vital imaging; electron microscopy; Cryo-EM; Cryo-ET
(This special issue belongs to the Section General Virology)
Advances in Measles Virus Research, Vaccine Development and Vaccination Strategies
edited by
submission deadline 31 Dec 2026 | Viewed by 186 | Submission Open
Keywords: measles virus; measles vaccine; vaccine-induced immunity; vaccine effectiveness; measles elimination strategies; immunity gaps
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Cell and Gene-Based Therapies for HIV
edited by
submission deadline 31 Dec 2026 | Viewed by 183 | Submission Open
Keywords: HIV cure strategies; gene editing; CAR-T cells; viral reservoir; stem cell transplantation
(This special issue belongs to the Section Human Virology and Viral Diseases)
Nonstandard Viral Genomes
edited by and Daniela Silva Ayala
submission deadline 31 Dec 2026 | Viewed by 182 | Submission Open
Keywords: nonstandard viral genomes; viral replication; viral evolution; competition; virus– host interactions; innate immunity; viral interference; genome rearrangements; pathogenesis; antiviral strategies; viral diversity; emerging viruses
(This special issue belongs to the Section General Virology)
Epstein–Barr Virus: Mechanisms in Autoimmunity and Oncogenesis
edited by Elliott SoRelle
submission deadline 31 Dec 2026 | Viewed by 176 | Submission Open
Keywords: Epstein– Barr virus (EBV); host– virus interactions; autoimmunity; inflammatory responses; viral oncogenesis; multiple sclerosis (MS); systemic lupus erythematosus (SLE); Burkitt lymphoma (BL); lymphoproliferative disorders (LPD); primary effusion lymphoma (PEL); extranodal NK/T cell lymphoma (ENKTL); nasopharyngeal carcinoma (NPC); gastric carcinoma (GC); chronic active EBV (CAEBV); hemophagocytic lymphohistiocytosis (HLH)
(This special issue belongs to the Section Human Virology and Viral Diseases)
Pathogenesis and Pathology of Equine Viral Infections submission deadline 31 Dec 2026 | Viewed by 169 | Submission Open
Keywords: equine viruses; equine pathology; viral pathogenesis; immunopathology; tissue tropism; organ-system pathology; host– virus interactions; diagnostic pathology; molecular pathology; horses/equids; viral diseases/veterinary virology
(This special issue belongs to the Section Animal Viruses)
Innovations and Emerging Challenges in Hepatitis C Virus Research
edited by and Jens Bukh
submission deadline 31 Dec 2026 | 1 articles | Viewed by 158 | Submission Open
Keywords: hepatitis C virus (HCV); direct-acting antivirals (DAAs); antiviral drug development; antiviral resistance; pathogenesis models; viral life cycle; host– pathogen interactions; immunology; innate and adaptive immune responses; vaccine research; global elimination strategies; molecular virology; cell culture studies; animal model studies; epidemiology and public health
(This special issue belongs to the Section Human Virology and Viral Diseases)
The Role of Bacteriophages in Salmonella Diversity, Pathogenicity and Surveillance
edited by , Yan Gao and Shengyi Han
submission deadline 31 Dec 2026 | Viewed by 115 | Submission Open
Keywords: bacteriophages; Salmonella; structural virology; prophage; antimicrobial resistance; phage typing; gene editing; genome evolution; phage therapy
(This special issue belongs to the Section Bacterial Viruses)
Basophils and Mast Cells in Respiratory Viral Pathogenesis submission deadline 31 Dec 2026 | Viewed by 84 | Submission Open
Keywords: respiratory viruses; mast cells; basophils; degranulation; antiviral response; pathology; respiratory virus immunology; immunotherapy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Biotechnological Applications of Extremophile Bacteriophages
edited by
submission deadline 31 Dec 2026 | Viewed by 57 | Submission Open
Keywords: thermophile; thermophage; thermophilic bacteriophage; extremophile; Geobacillus; Thermus; Archeae; hot spring; geothermal vent
(This special issue belongs to the Section Bacterial Viruses)
The Life Cycle of Human Papillomaviruses
edited by
submission deadline 31 Dec 2026 | Viewed by 48 | Submission Open
Keywords: human papillomavirus (HPV); viral life cycle; epithelial differentiation; gene expression regulation; oncogenesis
(This special issue belongs to the Section Human Virology and Viral Diseases)
PRRSV: Porcine Reproductive and Respiratory Syndrome Virus
edited by Jun Han and
submission deadline 31 Dec 2026 | Viewed by 14 | Submission Open
Keywords: PRRSV; viral evolution; virus– host interactions; pathogenesis; innate immunity; persistent infection; antiviral strategies; neutralizing antibodies; cellular immunity; vaccine development; disease prevention and control
(This special issue belongs to the Section Animal Viruses)
HIV and HTLV Infections and Coinfections (2nd Edition) submission deadline 1 Jan 2027 | 1 articles | Viewed by 1035 | Submission Open
Keywords: HTLV; HIV; infection; co-infection
(This special issue belongs to the Section Human Virology and Viral Diseases)
Avian Viruses and Antiviral Immunity
edited by and
submission deadline 15 Jan 2027 | 9 articles | Viewed by 7041 | Submission Open
Keywords: avian viruses; antiviral immunity; pathogenic mechanism; vaccine development; antiviral drugs; epidemiological dynamics; prevention and control; viral diseases of poultry and wild birds 
(This special issue belongs to the Section Animal Viruses)
Vaccines and Therapeutics Against Orthoflaviviruses
edited by and Liang Qiao
submission deadline 28 Jan 2027 | Viewed by 186 | Submission Open
Keywords: orthoflaviruses; vaccines; immunity; therapeutic agents; neutralizing antibodies; animal models; pathogenesis; protective efficacy
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Hepatitis Virus Genetic Heterogeneity: Impact in Epidemiology and Clinical Pathology
edited by , and Diego Flichman
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1998 | Submission Open
Keywords: viral hepatitis; molecular diagnostics; genotyping; molecular epidemiology; antiviral therapy; drug resistance; genomic surveillance
(This special issue belongs to the Section Human Virology and Viral Diseases)
Viral Non-Structural Proteins
edited by
submission deadline 31 Jan 2027 | Viewed by 710 | Submission Open
Keywords: viral genome; non-structural proteins; virus replication; vaccines; viral therapeutics
(This special issue belongs to the Section General Virology)
Adenovirus Cell and Immune Interactions 2026
edited by
submission deadline 31 Jan 2027 | Viewed by 300 | Submission Open
Keywords: adenovirus; gene therapy; vaccine; immune system; respiratory disease; structure
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Antiviral Protease Inhibitors
edited by Xufang Deng and
submission deadline 31 Jan 2027 | Viewed by 285 | Submission Open
Keywords: antiviral drug discovery; high-throughput screen; structure-guided drug design; artificial intelligence (AI)-based drug discovery; drug resistance; combination therapies; antiviral assay development; host-targeting antiviral
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Filoviruses: Pathogenesis, Immunity, and Countermeasures
edited by
submission deadline 31 Jan 2027 | Viewed by 178 | Submission Open
Keywords: filoviruses; ebola virus (EBOV); marburg virus (MARV); taï forest virus (TAFV); sudan virus (SUDV); reston virus (RESTV); bombali virus (BOMV); bundibugyo virus (BDBV); cytokine storm; viral pathogenesis; immunity; countermeasures; type-I interferons; inflammatory cytokines
(This special issue belongs to the Section Animal Viruses)
Viral Immune Evasion and Host Defense: Mechanisms and Therapeutic Targets submission deadline 31 Jan 2027 | Viewed by 146 | Submission Open
Keywords: viral immune evasion; host antiviral defense; emerging and re-emerging viruses; innate immune signaling; targeted antiviral therapies
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Impact of Evolution on Herpesvirus Pathogenesis
edited by
submission deadline 31 Jan 2027 | Viewed by 110 | Submission Open
Keywords: herpesviruses; evolution; pathogenesis
(This special issue belongs to the Section Human Virology and Viral Diseases)
Phage Ecology and Evolution in Animal Health
edited by
submission deadline 31 Jan 2027 | Viewed by 107 | Submission Open
Keywords: antimicrobial resistance; host– microbe interactions; phage ecology; phage evolution; veterinary microbiology
(This special issue belongs to the Section Bacterial Viruses)
Flaviviridae: Advances in Diagnosis, Prevention, and Control Strategies
edited by
submission deadline 31 Jan 2027 | Viewed by 67 | Submission Open
Keywords: flaviviridae; dengue virus; Zika virus; virus– host interactions; antiviral strategies; host-directed therapy; viral pathogenesis; emerging viruses
(This special issue belongs to the Section Animal Viruses)
Animal Herpesvirus: 3rd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 60 | Submission Open
Keywords: herpesviruses; innate immune responses; host adaptive immune responses; herpesvirus-host; interactions; susceptibility
(This special issue belongs to the Section Animal Viruses)
Pediatric Viral Gastroenteritis
edited by Filemon Bucardo and Sylvia Becker-Dreps
submission deadline 31 Jan 2027 | Viewed by 8 | Submission Open
Keywords: gastrointestinal track; rotavirus; norovirus; sapovirus; astrovirus
(This special issue belongs to the Section Human Virology and Viral Diseases)
Molecular Mechanisms and Clinical Manifestations of Persistent Viral Infections (2nd Edition)
edited by and Simone La Frazia
submission deadline 1 Feb 2027 | Viewed by 217 | Submission Open
Keywords: mammalian viruses; chronic infection; latent infection; HIV; HPV; HBV; HCV; HSV; pathogenetic mechanisms; molecular pathways; oncogenic processes; immunity; antiviral drugs; endogenous viral element
(This special issue belongs to the Section Human Virology and Viral Diseases)
Insect-Specific Viruses and Biological Control of Arboviruses submission deadline 6 Feb 2027 | 1 articles | Viewed by 1888 | Submission Open
Keywords: insect-specific virus; mosquito-specific virus; arbovirus; evolution; vaccine; biological control; interference
(This special issue belongs to the Section Invertebrate Viruses)
Viral Entry and Membrane Fusion
edited by Fabiana Carneiro
submission deadline 16 Feb 2027 | Viewed by 220 | Submission Open
Keywords: viral entry; membrane fusion; virus– host interactions; endocytosis; antiviral strategies
(This special issue belongs to the Section General Virology)
Viral Infections in Hematopoietic Stem Cell Transplant and Cellular Therapy Recipients, 2nd Edition
edited by Sanjeet Singh Dadwal
submission deadline 26 Feb 2027 | Viewed by 340 | Submission Open
Keywords: HSCT; GVHD; HHV6; CMV; adenovirus; BK and JC virus (polyomaviruses); HIV
(This special issue belongs to the Section Human Virology and Viral Diseases)
Plant Viral Pathogens: Innovations in Detection, Genetic Diversity, and Evolutionary Dynamics
edited by
submission deadline 28 Feb 2027 | 4 articles | Viewed by 6251 | Submission Open
Keywords: high-throughput sequencing; RT-PCR and qRT-PCR; genetic diversity; virus evolution; mutations; reassortment; recombination
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Emerging and Reemerging Plant Viruses in a Changing World: 2nd Edition
edited by
submission deadline 28 Feb 2027 | 3 articles | Viewed by 2645 | Submission Open
Keywords: emerging and re-emerging viruses; virus spillover; climate change and global trade; mixed infections; plant– virus– vector relationships
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Innovative Prophylactic and Therapeutics for the Treatment of Coronavirus Infection
edited by and Jun-Gyu Park
submission deadline 28 Feb 2027 | 2 articles | Viewed by 2554 | Submission Open
Keywords: prophylactic; therapeutics; SARS-CoV-2; viral variants; antivirals
(This special issue belongs to the Section Coronaviruses)
Cellular Mechanisms Regulating HIV Replication, 2nd Edition
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 1917 | Submission Open
Keywords: HIV-1; HIV-1 replication; host factors
(This special issue belongs to the Section Human Virology and Viral Diseases)
Application of Genetically Engineered Plant Viruses, 2nd Edition
edited by and Chu-Hui Chiang
submission deadline 28 Feb 2027 | 1 articles | Viewed by 953 | Submission Open
Keywords: plant virus; infectious clone; viral vector; virus-induced gene silencing (VIGS); virus-like particles (VLPs); cross-protection
(This special issue belongs to the Section Viruses of Plants, Fungi and Protozoa)
Immune Mechanisms Against Respiratory Viral Pathogens
edited by Telugu Akula Narasaraju and Sunil More
submission deadline 28 Feb 2027 | Viewed by 342 | Submission Open
Keywords: respiratory viral infections; innate and adaptive immunity; host– pathogen interactions; inflammatory response; therapeutic interventions
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Acute and Persistent Immune Responses to Respiratory Infections and Vaccines—Mucosal and Systemic
edited by Julian Tang
submission deadline 28 Feb 2027 | Viewed by 268 | Submission Open
Keywords: respiratory viruses; coronaviruses; SARS-CoV-2; influenza; parainfluenza; RSV (respiratory syncytial virus); adenoviruses; rhinoviruses; enteroviruses; host immune responses; mucosal immunity; systemic immunity; clinical disease severity; virus transmission; infection control; vaccine responses
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Immune Responses and Antiviral Strategies Against Emerging RNA Viruses
edited by
submission deadline 28 Feb 2027 | Viewed by 12 | Submission Open
Keywords: host–virus interactions; viral recombination; immune evasion; systems virology
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Bats as Viral Reservoirs: From Discovery to Pandemic Preparedness submission deadline 28 Feb 2027 | Viewed by 3 | Submission Open
Keywords: virus; bat; reservoir; infection
(This special issue belongs to the Section Animal Viruses)
Novel Antiviral Strategies: Direct-Acting and Host-Directed Antivirals
edited by and
submission deadline 28 Feb 2027 | Submission Open
Keywords: direct-acting antivirals (DAA); host-directed antivirals (HDA); antiviral resistance evolution; host– pathogen interactome; broad-spectrum efficacy; structure-based drug design; targeted protein degradation; one health therapeutics
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
Viral Pneumonia: Recent Advances and Prospects
edited by
submission deadline 31 Mar 2027 | Viewed by 460 | Submission Open
Keywords: viral pneumonia; viral lung infections; respiratory viruses; influenza viruses; respiratory syncytial virus (RSV); coronaviruses (such as SARS-CoV-2); viral persistence; molecular mechanisms; host immune responses; innate and adaptive immunity; immune– metabolic interactions; alveolar regeneration; dysregulated inflammation; epithelial and endothelial repair mechanisms; single-cell omics; organoid models; spatial profiling
(This special issue belongs to the Section General Virology)
Iridoviruses, 3rd Edition submission deadline 31 Mar 2027 | Viewed by 228 | Submission Open
Keywords: iridovirus; viral immune evasion; anti-viral immune responses; viral vaccine; viral pathogenesis; viral epidemiology
(This special issue belongs to the Section Animal Viruses)
New Advances in Small Ruminant Lentiviruses: Genetic Variability, Diagnostic Challenges, and Control Strategies
edited by and
submission deadline 31 Mar 2027 | Viewed by 226 | Submission Open
Keywords: caprine arthritis encephalitis virus (CAEV); cross-species transmission; control and Eradication program; genetic variability; Maedi-Visna virus (MVV); molecular diagnosis; pathology; serological assays; small ruminant lentiviruses (SRLV); wildlife reservoirs
(This special issue belongs to the Section Animal Viruses)
Virioplankton and Climate Change
edited by
submission deadline 31 Mar 2027 | Viewed by 167 | Submission Open
Keywords: viruses; climate change; bacteriophages; viral shunt; bacteria; picophytoplankton
(This special issue belongs to the Section Bacterial Viruses)
Human T Cell Leukemia Virus
edited by
submission deadline 31 Mar 2027 | Viewed by 94 | Submission Open
Keywords: infection prevention; vaccines; anti-viral drugs to prevent infection; measures against prejudice and discrimination; public health initiatives; risk evaluation by biomarkers; early therapeutic intervention; new treatment strategies
(This special issue belongs to the Section Human Virology and Viral Diseases)
Molecular Mechanisms and Structural Biology of High-Pathogenicity RNA Viruses submission deadline 31 Mar 2027 | Viewed by 79 | Submission Open
Keywords: high-pathogenicity RNA viruses; structural virology; virus– host interactions; viral replication complexes; intrinsically disordered proteins; cryo-electron microscopy; immune evasion mechanisms; viral protein structure; phase separation in viral infection; antiviral target discovery
(This special issue belongs to the Section General Virology)
HIV Reservoirs, Latency, and the Factors Responsible (2nd Edition)
edited by Yuyang Tang and
submission deadline 1 Apr 2027 | Viewed by 52 | Submission Open
Keywords: HIV; reservoirs; HIV latency; persistence; HIV eradication; HIV cure; HIV vaccines
(This special issue belongs to the Section Human Virology and Viral Diseases)
The Interplay Between Viral Infections and Autoimmune Diseases
edited by
submission deadline 30 Apr 2027 | 2 articles | Viewed by 3092 | Submission Open
Keywords: viral infections; autoimmune diseases; molecular mimicry; epitope spreading; persistent antigen & tissue‐specific antiviral responses; biomarkers & precision stratification; vaccine-related immune dynamics; single-cell & spatial omics; post-viral syndromes; immune repertoire; immune-repertoire alteration syndrome
(This special issue belongs to the Section Human Virology and Viral Diseases)
Spectroscopic Advances in Virology: Technique Development and Applications to Viral Structure and Function
edited by
submission deadline 30 Apr 2027 | Viewed by 106 | Submission Open
Keywords: viral dynamics; structural virology; biophysical methods; nuclear magnetic resonance; fluorescence spectroscopy; electron paramagnetic resonance; virus– host interaction; antiviral design
(This special issue belongs to the Section General Virology)
Antiviral Agents and Peptides: Discovery, Mechanisms, and Therapeutic Applications
edited by
submission deadline 30 Apr 2027 | Viewed by 70 | Submission Open
Keywords: antiviral agents; antiviral peptides (AVPs); drug discovery; drug resistance; peptide engineering; mechanisms of antiviral action; structure– activity relationship (SAR); high-throughput screening; AI-assisted design
(This special issue belongs to the Section Viral Immunology, Vaccines, and Antivirals)
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