Botulinum Toxins: Past Successes and New Goals
A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Bacterial Toxins".
Deadline for manuscript submissions: 31 August 2026
Special Issue Editor
Interests: botulinum toxin; dystonia; cervical dystonia; sialorrhea; Parkinson’s disease; blepharospasm
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Botulinum toxin has been used therapeutically since the 1980s, initially for the treatment of cervical dystonia, hemifacial spasm and blepharospasm, and then for focal spasticity, bladder dysfunction, excessive sweating, and migraines. These indications were approved, and subsequent developments in its therapeutic use has been tremendous. Unfortunately, the innovative momentum faded over time as demands became increasingly stringent, and manufacturers gradually lost interest in less common indications. Even today, there are many promising indications for which approval has not yet been granted. I was fortunate enough to witness this success story, but it is upsetting that the dynamism of the early days has somewhat diminished. The last great wave of enthusiasm I experienced was with the introduction of ultrasound in our field.
With this Special Issue, we aim to take stock of the current situation and point out new avenues: not with nostalgia, not with a know-it-all attitude, but with the mindset of the early days. This will allow us to develop new indications and improve existing applications. I hope you will accompany me in this journey.
Prof. Dr. Wolfgang Jost
Guest Editor
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Keywords
- botulinum neurotoxin
- dystonia
- spasticity
- sialorrhea
- pain
- future aspects
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