You are currently viewing a new version of our website. To view the old version click .

Toxics, Volume 13, Issue 7

July 2025 - 92 articles

Cover Story: The 6-PPD quinone (6-PPDQ) is a derivative from 6-PPD, an antioxidant added in tires. Using Caenorhabditis elegans as an animal model, leucine content was reduced by 6-PPDQ at environmentally relevant concentrations. This leucine reduction in 6-PPDQ-exposed nematodes was due to both inhibition in leucine adsorption and increase in leucine catabolism. Alteration in expression of genes governing leucine catabolism was linked to a reduction in NADH and FADH2 contents and mitochondrial dysfunction in 6-PPDQ-exposed nematodes, which could be inhibited by following pharmacological treatment with leucine. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (92)

  • Review
  • Open Access
2 Citations
1,406 Views
24 Pages

21 July 2025

Abandoned smelting sites in karst terrain pose a serious environmental problem due to the complex relationship between specific hydrogeological elements and heavy metal contamination. This review combines work from across the globe to consider how ka...

  • Article
  • Open Access
1,458 Views
20 Pages

The Crime of Vehicular Homicide in Italy: Trends in Alcohol and Drug Use in Fatal Road Accidents in Lazio Region from 2018 to 2024

  • Francesca Vernich,
  • Leonardo Romani,
  • Federico Mineo,
  • Giulio Mannocchi,
  • Lucrezia Stefani,
  • Margherita Pallocci,
  • Luigi Tonino Marsella,
  • Michele Treglia and
  • Roberta Tittarelli

19 July 2025

In Italy, the law on road homicide (Law no. 41/2016) introduced specific provisions for drivers who cause severe injuries or death to a person due to the violation of the Highway Code. The use of alcohol or drugs while driving constitutes an aggravat...

  • Systematic Review
  • Open Access
1 Citations
2,598 Views
24 Pages

Nephrotoxicity of New Antibiotics: A Systematic Review

  • Panagiotis Stathopoulos,
  • Laura T. Romanos,
  • Charalampos Loutradis and
  • Matthew E. Falagas

19 July 2025

Drug-induced nephrotoxicity is a common and serious problem in clinical practice. We conducted a systematic review of studies reporting nephrotoxicity events associated with antibiotics approved since 2018. The agents assessed included aztreonam/avib...

  • Article
  • Open Access
2,543 Views
19 Pages

Impact of Polystyrene Microplastics on Human Sperm Functionality: An In Vitro Study of Cytotoxicity, Genotoxicity and Fertility-Related Genes Expression

  • Filomena Mottola,
  • Maria Carannante,
  • Ilaria Palmieri,
  • Lorenzo Ibello,
  • Luigi Montano,
  • Mariaceleste Pezzullo,
  • Nicola Mosca,
  • Nicoletta Potenza and
  • Lucia Rocco

19 July 2025

Polystyrene microplastics (PS-MPs) released in the environment reportedly affect the reproduction of various organisms, induced oxidative stress and apoptosis, resulting in altered sperm parameters. In this in vitro study, we tested the cytotoxicity...

  • Article
  • Open Access
802 Views
23 Pages

Evaluating Copper-Induced Oxidative Stress in Germinating Wheat Seeds Using Laser Photoacoustic Spectroscopy and EPR Techniques

  • Mioara Petrus,
  • Cristina Popa,
  • Ana-Maria Bratu,
  • Alexandra Camelia Joita and
  • Vasile Bercu

18 July 2025

Copper is an essential micronutrient for plants, but excessive levels can induce toxicity and impair physiological functions. This study evaluates the toxic effects of copper sulfate (CuSO4) on the germination of common wheat (Triticum aestivum), wit...

  • Article
  • Open Access
1 Citations
524 Views
13 Pages

Environmental Risk and Management of Iron Tailings in Road Subgrade

  • Xiaowei Xu,
  • Dapeng Zhang,
  • Jie Cao,
  • Chaoyue Wu,
  • Yi Wang,
  • Jing Hua,
  • Zehua Zhao,
  • Jun Zhang and
  • Qi Yu

17 July 2025

The utilization of iron tailings in road construction poses significant environmental risks due to the complex release mechanisms of pollutants and varying regional conditions. This study integrates an exponential decay model with an instantaneous po...

  • Article
  • Open Access
987 Views
16 Pages

Thermoset Polyester Resin Microplastics: Effects on Enzymatic Biomarkers and Toxicological Endpoint Responses of Eisenia fetida Earthworms

  • David Amaya-Vías,
  • Gemma Albendín,
  • Vanessa Aranda-Quirós,
  • Rocío Rodríguez-Barroso,
  • Dolores Coello and
  • Juana María Arellano

17 July 2025

Thermosets are plastic composite materials widely used in many industrial sectors of modern society with an increasing presence in the environment. The adverse effects of this material on environmental compartments and biota of thermosets are still u...

  • Article
  • Open Access
1,341 Views
32 Pages

Forty Years After Chernobyl: Radiocaesium in Wild Edible Mushrooms from North-Eastern Poland and Its Relevance for Dietary Exposure and Food Safety

  • Iwona Mirończuk-Chodakowska,
  • Jacek Kapała,
  • Karolina Kujawowicz,
  • Monika Sejbuk and
  • Anna Maria Witkowska

17 July 2025

Wild-growing edible mushrooms are known to bioaccumulate radionuclides from their environment, particularly the natural isotope potassium-40 (40K) and anthropogenic cesium-137 (137Cs). However, region-specific data for commercially relevant species i...

  • Article
  • Open Access
885 Views
17 Pages

Immunotoxicity Studies on the Insecticide 2-((1-(4-Phenoxyphenoxy)propan-2-yl)oxy)pyridine (MPEP) in Hsd:Harlan Sprague Dawley SD® Rats

  • Victor J. Johnson,
  • Stefanie C. M. Burleson,
  • Michael I. Luster,
  • Gary R. Burleson,
  • Barry McIntyre,
  • Veronica G. Robinson,
  • Reshan A. Fernando,
  • James Blake,
  • Donna Browning and
  • Stephen Cooper
  • + 2 authors

17 July 2025

The broad-spectrum insect growth regulator (IGR) and insecticide 2-((1-(4-Phenoxyphenoxy)propan-2-yl)oxy)pyridine (MPEP; also known as pyriproxyfen) is increasingly being used to address public health programs for vector control, initiated by the spr...

  • Article
  • Open Access
767 Views
23 Pages

16 July 2025

Petroleum-contaminated soil is an increasingly severe environmental issue. The integration of phytoremediation and microbial remediation can effectively mitigate their individual limitations and enhance remediation efficiency. In this study, four new...

of 10

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Toxics - ISSN 2305-6304Creative Common CC BY license