Modern Formulation and Applications of Probiotics
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 2
Special Issue Editors
Interests: assessment of biocompatibility; drug delivery system formulation; application of macromolecules; characterization of dosage forms; in vitro dissolution studies; SEDDS
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Probiotics are living microorganisms that, when administered in adequate amounts, confer health benefits to the host. In recent years, formulation technologies have advanced considerably, improving probiotic stability, bioavailability, and targeted delivery. While traditional probiotic products remain popular, modern strategies—including microencapsulation, lyophilization, and synbiotic formulations—offer enhanced protection from gastrointestinal conditions and ensure viability upon intestinal delivery.
The applications of probiotics have expanded well beyond gut health. Current research highlights their role in managing metabolic disorders (e.g., obesity and type 2 diabetes), modulating the immune system, supporting mental health via the gut–brain axis, and contributing to skin and oral health. Evidence also supports their effectiveness in preventing antibiotic-associated diarrhea and promoting overall microbiome balance.
The development of next-generation probiotics, including genetically engineered strains and microbiome-derived candidates, holds promise for personalized and precision medicine. However, ongoing challenges remain regarding strain specificity, optimal dosage, and global regulatory harmonization.
The aim of this Special Issue on Modern Formulation and Applications of Probiotics is to highlight recent progress and novel approaches in this dynamic field. We welcome original research articles and comprehensive reviews that address innovative formulation techniques, characterization strategies, mechanistic insights, and translational aspects of probiotic science. As Guest Editors, we warmly invite you to contribute your latest findings and perspectives to advance scientific discourse on modern probiotics.
Prof. Dr. Ildikó Bácskay
Dr. Dávid Sinka
Guest Editors
Manuscript Submission Information
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Keywords
- probiotics
- nanoformulation
- microencapsulation
- targeted delivery
- next-generation probiotics
- synbiotics
- gut–brain axis
- personalized medicine
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