Developing Drug Delivery Approaches for Both Phage Therapeutics and Phage-Based Vectors
A Special Issue of Pharmaceutics (ISSN 1999-4923) belonging to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (31 July 2026) | Viewed by 2189
Editors
Interests: phage therapy; drug delivery; bacteriophage; phage; antimicrobials; spray-drying; drying; stability; phage isolation; phage activity
Special Issue Information
Dear Colleagues,
The development of standardized approaches will facilitate the establishment of phage-based drug delivery systems. Bacteriophages, or phages, are viruses that specifically target and eliminate bacterial populations, making them excellent candidates for the development of targeted drug delivery therapeutics. This innovative approach leverages the natural ability of phages to navigate biological and chemical barriers and deliver therapeutic agents directly to infected cells, enhancing efficacy while minimizing side effects.
Recent research has focused on optimizing the delivery of phage vectors by encapsulating them like various drugs, including antibiotics, anticancer agents, and gene therapies. In particular, the specific phage doses have been shown to improve drug stability and bioavailability, ensuring that therapeutic agents effectively reach their targets. Engineering phages to display specific ligands further enhances targeting precision, enabling more effective treatment of bacterial infections. This approach enhances phage therapy's potential.
Therefore, this Special Issue aims to highlight the most relevant and innovative original research articles and reviews on phage technology in drug delivery systems. By exploring the potential of phage-based systems, including oral formulations, these studies underscore the versatility of phage technology to address pressing challenges in modern medicine and pave the way for more effective and personalized treatments in the pharmaceutical sciences.
Dr. Tea Glonti
Dr. Daniel De Vos
Guest Editors
Manuscript Submission Information
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Keywords
- phage vector
- drug delivery
- phage therapy
- phage technology
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