Selective Antitumor Therapy Based on Nanotechnology
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (15 September 2022) | Viewed by 3386
Special Issue Editors
Interests: nanotechnology; bioconjugation; multifuntionalization; polymeric nanoparticles; drug delivery; nanotheranostic
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, nanotechnology has been widely implemented in cancer treatment due to the importance of nanoparticles as drug delivery systems. The continuous development in this area provides alternative approaches to overcome the limitations of conventional cancer therapy. Drug targeting by using functionalized nanoparticles that improve their pharmacokinetic properties was one of the first milestones to be achieved, obtaining highly specific, non-toxic and biocompatible nanoformulations. The current trend is towards personalized medicine through a paradigm shift in the orientation towards new targets, such as cellular organelles that increase drug efficacy. One of the current key challenges is the design of nanodevices that avoid cellular drug resistance mechanisms and improve the penetration of solid tumors. On the other hand, immunotherapy offers new opportunities for nanomedicine to label tumor cells for recognition by the immune system. Advanced tissue models that reflect tumor heterogeneity are being developed to establish safe and effective nanoformulations. Additionally, a current challenge is to deepen the mechanisms of action of the developed nanosystems.
This Special Issue aims is to publish original research articles and reviews focusing on the latest developments in nanotechnology-based targeted antitumor therapy. This Special Issue welcomes research findings that help to improve cancer therapy by applying strategies based on nanoparticles, such as polymeric nanoparticles, inorganic nanoparticles, liposomes, dendrimers, exosomes, etc.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: targeted drug delivery, theranostics, DNA nanotechnology, nanovectors, gene delivery, gene editing, strategies to overcome drug resistance, immunotherapy, tumor models to validate nanoformulations, the mechanisms of action of nanodevices, nanotoxicology, the preclinical characterization of nanodevices, bio-inspired nanomaterials, exosomes for cancer therapy, etc.
We look forward to receiving your contributions.
Dr. Rosario M. Sanchez-Martin
Dr. Victoria Cano-Cortés
Guest Editors
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Keywords
- nanotechnology
- drug delivery
- nucleic acid delivery
- cancer
- nanomedicine
- targeted therapy
- drug resistance
- bio-inspired nanomaterials
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