Nanobiocomposites for Drug Delivery

Dear Colleagues,

Over the last two decades, the advancement of drug delivery (DD) devices has increased exponentially because several problems associated with drug administration and toxicity were reported. Considerable improvements have been carried out for the progress of DD systems to accomplish better patient compliance with lower toxicity, improved pharmacokinetic profile, and proper targeting. Under this framework, nanocomposites, defined as multiphase material with at least one dimension less than 100 nm and/or phase components with distances at the nanoscale, showed new alternatives for the development of novel DD structures. More recently, the availability of a large number of biomolecules with high purity and the recent advances in biophysical techniques to analyze and characterize the interactions between the nanocomposites open a wide window for the development of DD nanobiocomposites (NBCs). One of main advantages of NBCs is the myriad of potential molecules that could be blended, including nanoparticles, biomolecules, and inorganic and/or organic compounds, which provide unique NBCs for any DD applications with the potential benefits of being naturally responsive to the environmental conditions and biodegradability without the release of undesirable toxic by-products. The present Special Issue will cover different approaches for the application of NBCs for drug delivery, which will involve improved drug efficacy, bioavailability, the control release of drugs and/or bioactive molecules (and their kinetic, novel, NBC-targeted delivery), and other topics of interest to develop novel NBCs for drug delivery applications.

Prof. Dr. Guillermo R. Castro
Dr. Fabio Furlan Ferreira
Guest Editors

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