Advances in Anticancer Drug Metabolism Research: Implications for Personalized Therapeutics

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 198

Special Issue Editors


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Guest Editor
LAQV/REQUIMTE, Laboratory of Bromatology and Hidrology, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: cardio-oncology; anticancer drugs; cardiotoxicity; in vivo; in vitro; molecular biology; inflammation; oxidative stress; metabolism; biotransformation

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Guest Editor
LAQV/REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: pharmacology; metal-based drugs; in vitro; in vivo; oncology; pharmacokinetics; anticancer drugs; biomarkers
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Guest Editor
Faculty of Health Sciences, University Fernando Pessoa, Rua Carlos da Maia, 4200-150 Porto, Portugal
Interests: toxicology; drugs of abuse; amphetamines; synthetic cathinones; psychoactive substances; toxicometabolomics; cancer metabolomics; biomarkers; hepatotoxicity; nephrotoxicity; cardiotoxicity; oxidative stress
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Guest Editor
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, 1649-003 Lisbon, Portugal
Interests: phenolic compounds; immunometabolism; food nanotechnologies; nanoencapsulation; drug delivery systems; biodisponibility; colorectal cancerolic compounds; persimmon; food science; functional foods; biochemistry; haematology; in vitro/in vivo inflammation and cancer models
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to the launch of a Special Issue titled "Advances in Anticancer Drug Metabolism Research: Implications for Personalized Therapeutics". This Special Issue aims to underscore the critical role of drug metabolism in determining the efficacy and safety of anticancer therapies. A deeper understanding of metabolic pathways and the genetic factors influencing drug biotransformation is essential for optimizing therapeutic outcomes and driving the development of personalized medicines.

We welcome original research articles and comprehensive reviews on a variety of topics, including, but not limited to, the following:

  • Metabolic pathways of anticancer drugs;
  • Pharmacogenomics and precision oncology;
  • Drug–drug interactions in cancer therapies;
  • Biomarkers of drug response and/or toxicity;
  • Emerging therapeutic targets and innovative strategies.

Submissions exploring interdisciplinary approaches that increase our understanding of drug metabolism's impact on personalized cancer treatment are particularly welcome. These collaborations have the potential to drive significant advancements in improving patient outcomes, encompassing survival rates and quality of life.

We look forward to your contributions to this Special Issue, thus enhancing the field of anticancer drug metabolism research and its translation into tailored therapeutic strategies.

Dr. Ana Reis-Mendes
Dr. Martin Vojtek
Dr. Márcia Carvalho
Dr. Rosa Direito
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anticancer drug metabolism
  • personalized medicine
  • drug interactions
  • therapeutic efficacy
  • drug safety
  • pharmacogenomics

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Published Papers

This special issue is now open for submission.
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