Skeletal muscle aging and related diseases are characterized by progressive loss of muscle mass, strength, and metabolic function. Central to these processes is mitochondrial dysfunction, which impairs energy metabolism, redox homeostasis, and proteo...
Strenuous exercise involving eccentric muscle actions induces skeletal muscle damage resulting in delayed onset muscle soreness (DOMS). Antioxidant supplementation, such as astaxanthin (AX), may alleviate muscle injury following intense exercise. The...
Skeletal muscle function is vital for locomotion, posture, and metabolism, significantly impacting overall health and preventing falls, morbidity, and mortality, especially in elderly populations. This systematic review investigates the influence of...
The skeletal muscle is a highly plastic tissue that shows a remarkable adaptive capacity in response to acute and resistance exercise, and modifies its composition to adapt to use and disuse, a process referred to as muscle plasticity. Heat shock pro...
Background: Musculoskeletal pain is a non-negligible multifaceted condition affecting more than 30% of the global population. Superficial heat therapy (HT), through increasing tissue temperatures, plays a role in increasing local metabolism and funct...
This systematic review aims to evaluate the impact of hormonal fluctuations during the menstrual cycle on the performance of female athletes. Methods: Following PRISMA guidelines, a comprehensive search was conducted in Scopus, Web of Science, and Pu...
Eculizumab is a monoclonal antibody blocking the terminal complement protein C5. As demonstrated in the phase III randomized, placebo-controlled, REGAIN clinical trial, eculizumab is efficacious in acetylcholine receptor antibody (AChR-Ab)-positive r...
Muscle strength and mass strongly influence performance. The role of the trunk, upper limbs, and lower limbs in a specific performance is important but unclear in terms of muscle strength, muscle mass, and the degree of influence of each part. Standi...
Fatty infiltration of the rotator cuff muscles is very common following rotator cuff tears and is one of the most important factors in determining treatment. Current clinical practice relies on subjective evaluation of fatty infiltration through cate...
Neuromuscular diseases (NMD) cover a broad spectrum of different rare diagnoses in which the primary lesion is in the peripheral nervous system. The impairment caused by an NMD does not only interfere with physical status but also has a clear impact...
Exercise-induced muscle injury and the subsequent release of Damage-Associated Molecular Patterns (DAMP) result in soreness and inflammation. Dietary supplements may accelerate the rate of recovery by supporting resolution of inflammation. The purpos...
Skeletal muscle is a complex tissue comprising multinucleated and post-mitotic cells (i.e., myofibers). Given this, skeletal muscle must maintain a fine balance between growth and degradative signals. A major system regulating the remodeling of skele...
Skeletal muscle MRI studies in limb-girdle muscular dystrophy (LGMD) have increased over the past decades, improving the utility of MRI as a differential diagnostic tool. Nevertheless, the relative rarity of individual genotypes limits the scope of w...
This study’s primary objective was to examine the differences in body composition, abdominal strength, absolute and relative power, handgrip strength, one repetition maximum for squat and bench press, and the maximum count of push-up and sit-up...
Despite ongoing efforts, the relationship between groin strength and injury remains unclear. The challenge of accurately predicting injuries presents an opportunity for researchers to develop prevention strategies to reduce the occurrence of such inj...
Background: Algometry is a validated and reliable measurement tool, but there are still no reliable data for the different algometers used by different raters in the same participant. Objective: The aim of this study was to determine the intra-reliab...
This study examined the association between knee proprioception, strength, and functional symmetry in healthy individuals using isokinetic strength tests, proprioception assessments, and hop tests. Twenty young, healthy adults (mean age 26.5 ±...
Limb-girdle muscular dystrophies (LGMDs) represent a group of muscle diseases due to monogenic mutations encoding muscle proteins that are defective for heterozygous and homozygous mutations prevalent in certain regions. Advances in knowledge of thei...
Background/Objectives: CrossFit® is one of the most popular yet controversial training regimens. Some groups extol the positive effects of its practice, while others argue that it is unsafe and that there is limited information. The aim of this s...
Dietary behaviors influence nutrient intake and body composition, both of which are important determinants of an individual’s overall health. This study investigated sex differences in the associations between dietary behaviors and body composi...
We describe two cases of myofibrillar myopathies, due to different gene mutations. The first was a girl with cardiomyopathy and sensory axonal neuropathy that underwent cardiac transplantation at 15 years and suffers from rotatory scoliosis due to BA...
This comprehensive review focuses on the dynamics of branched-chain amino acids (BCAAs) metabolism and its clinical implications in chronic liver disease, with emphasis on the emerging concept of muscle–liver crosstalk. BCAAs, indispensable for...
Myokines released by exercise are identified as factors that can influence a person’s health and wellbeing. While myokine secretion in response to an acute bout of endurance and resistance-type exercise has been examined, the influence of resis...
Isometric strength is widely used to monitor training adaptations, assess neuromuscular fatigue, and play a critical role in the maintenance of muscle health. This study assessed repeatability (intra-session) and reliability (inter-session) of a forc...
The assessment of joint ranges is an essential component of the physical examination, enabling monitoring and follow-up. Additionally, it is a key component of muscle mobility assessment. Smartphone applications for range-of-motion assessments offer...
Background/Aims: The pelvic floor muscles are important structures involved in pelvic floor tone, pelvic organ support, and continence. The aim of this study was to perform an update on the pelvic floor muscle structure and function alterations of wo...
Light therapy has been shown to produce several beneficial physiological effects in a wide range of tissues. The musculoskeletal system can be irradiated with deeply penetrating wavelengths in near infrared (NIR) regions. Photobiomodulation therapy (...
Hamstring strain injuries (HSI) are common in soccer and remain challenging to predict, as traditional risk factors often fail to capture the multifactorial nature of injury susceptibility. This prospective cohort study aimed to develop and internall...
This systematic review and meta-analysis was conducted to evaluate the effectiveness of the FIFA 11+ injury prevention programme, a neuromuscular training intervention involving muscular strength, proprioception, balance, and plyometric exercises, in...
The aim of the study was to analyze muscle activation in the three positions of the deadlift (DL). Twenty male participants (33.4 ± 3.9 years; 42.2 ± 9.1 months of experience with DL; 91.0 ± 14.8 kg; and 1.78 ± 0.06 m) pul...
Firefighters are at a higher risk for experiencing back pain due to the nature of their job, but physical fitness may help to reduce this risk. Therefore, the primary purpose of this study was to determine if a correlation between subjective back pai...
Background: Falls risk assessment tools are used in hospital inpatient settings to identify patients at increased risk of falls to guide and target interventions for fall prevention. In 2022, Western Health, Melbourne, Australia, introduced a new fal...
Electromyographic biofeedback (EMG-BF) is a technique that can contribute to the improvement of muscle tone and control in the rehabilitation process after injury. The aim of this research was to determine the effectiveness of EMG-BF in increasing th...
Percussive therapy devices have been proven effective at reducing muscle inflammation, soreness, and tension and improving the range of motion before or after exercise. However, there is a notable lack of research on percussive therapy intra-exercise...
Measuring the bicep femoris long head fascicle length via the use of diagnostic ultrasound has become common practice within elite sport, using single images of between 4 and 6 cm. No study to date has compared single image estimations in terms of th...
Previous studies have revealed decreased proprioception and perception of joint position in elderly adults. Joint position sense, indicating an individual’s ability to perceive the position of limbs without visual aid, is essential for everyday...
Medial gastrocnemius silent contractures (MGSCs) are prevalent, notably impacting functional status and increasing the risk of foot and ankle disorders, especially among aging populations. Although traditionally managed by podiatrists and physiothera...
Exertional rhabdomyolysis (ER) is a condition where muscle breakdown occurs after intense and unaccustomed exercise in healthy individuals. It is characterized by muscle pain, weakness, and myoglobinuria, potentially leading to acute kidney injury an...
Maximal eccentric (MES) and isometric (MIS) muscle strength may enhance vertical jump performance by facilitating preloading and reducing energy loss during the eccentric (ECC) phase of the stretch-shortening cycle (SSC). However, the contributions o...
Background: The presence of sensorimotor control deficits in adolescent idiopathic scoliosis compared to typically developed adolescents is supported by the literature but lacks reliability studies for assessment in this population. This study aimed...
People affected by mitochondrial myopathies (MITOs) are thought to have impaired skeletal muscle oxygenation. The aims of this study were to measure skeletal muscle mitochondrial capacity in MITO participants and able-bodied (AB) participants and eva...
Turkesterone is a naturally occurring plant steroid touted for its medicinal, pharmacological, and biological properties with no reported adverse side effects compared with traditional anabolic androgenic steroids (AAS). However, this ostensible enha...
Improving and maintaining an ideal body composition is important for sporting achievement and good health. Body composition assessment is therefore a tool used to monitor training and to evaluate the objectives of a training plan for health purposes....
Boxing is a sport that has a high level of oxygen use within the Rectus Femoris muscle, with recovery between rounds important to subsequent performance. The study aimed to determine muscle oxygen use in male and female professional boxers in respons...
The Nordic hamstring exercise (NHE) is effective at decreasing hamstring strain injury risk. Limited information is available on the in vivo mechanics of the bicep femoris long head (BFLH) during the NHE. Therefore, the purpose of this study was to o...
Ergogenic supplements are becoming increasingly popular in the diet of trained individuals, due to their potential benefits. Ashwagandha (Withania somnifera) is one of the supplements that has recently grown in popularity. Despite growing interest, i...
Baicalin is a natural flavonoid that has anti-apoptotic and anti-inflammatory effects. It shows some beneficial effects on muscle atrophy. However, its effects on age-related muscle atrophy are poorly understood. In this paper, we investigated whethe...
Aim: The study developed and validated AppER, an mHealth tool for informal caregivers of children with Duchenne Muscular Dystrophy, and examined differences between app users and non-users. Methods: Four phases were followed: (1) focus groups with ex...
Blood flow restriction exercise (BFRE), which partially restricts arterial inflow and occludes venous outflow to the limbs, has gained attention for its potential to elevate serum brain-derived neurotrophic factor (BDNF), a key mediator in the muscle...
Background: Expression of maximal and rapid force in the hip, knee, and plantar flexors is important for athletic performance in female soccer. This study was designed to determine the effect of relative isometric strength in the isometric mid-thigh...
