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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Compounds and Functional Biopolymers in Food Packaging submission deadline 28 Feb 2027 | Viewed by 61 | Submission Open
Keywords: active packaging; biopolymers; natural compounds; bioactive compounds; sustainability; agro-food by-products; e-circular economy
(This special issue belongs to the Section Food Chemistry)
Metal–Organic Frameworks in Biological Systems: Synthesis, Bioactivity, and Biomedical Applications submission deadline 28 Feb 2027 | Viewed by 57 | Submission Open
Keywords: metal–organic frameworks (MOFs); biological and biomedical application; drug delivery; antimicrobial; anticancer; structure–activity relationships
(This special issue belongs to the Section Organometallic Chemistry)
Research and Application of Liquid Chromatography for the Separation and Quantification of Bioactive Compounds
edited by
submission deadline 28 Feb 2027 | Viewed by 53 | Submission Open
Keywords: liquid chromatography; method validation; bioactive compounds; sample preparation; separation; determination
(This special issue belongs to the Section Analytical Chemistry)
Safety Control and Quality Analysis in Food Processing submission deadline 28 Feb 2027 | Viewed by 45 | Submission Open
Keywords: food safety; food quality; NIR spectroscopy; FT-NIR; chemometrics; food adulteration; non-destructive analysis; food processing; authentication; multivariate analysis
(This special issue belongs to the Section Food Chemistry)
Non-Conventional Processing Technologies for Molecular Modification of Food Biomolecules: Structure–Function Relationships submission deadline 28 Feb 2027 | Viewed by 36 | Submission Open
Keywords: non-conventional technologies; food biomolecules; molecular modification; structure-function relationships; ultrasound; high-pressure processing; cold plasma; pulsed electric fields
(This special issue belongs to the Section Food Chemistry)
Bioactive Compounds from Medicinal and Aromatic Plants: Chemistry, Mechanisms, and Applications submission deadline 28 Feb 2027 | Viewed by 31 | Submission Open
Keywords: natural products chemistry; medicinal plants; aromatic plants; plant secondary metabolites; bioactive compounds; phytochemistry; compound isolation; biological activity; mechanism of action; green extraction techniques; drug discovery; semi-synthesis; natural product-based therapeutics; cosmeceuticals; functional foods
(This special issue belongs to the Section Natural Products Chemistry)
Theoretical and Computational Approaches to Natural Products and Their Derivatives
edited by
submission deadline 28 Feb 2027 | Viewed by 17 | Submission Open
Keywords: natural products; natural product derivatives; quantum-chemical calculations; chemical reactivity descriptors; thermodynamic properties; spectroscopic characteristics; structure-activity relationship; molecular docking; molecular dynamics simulations; pharmacophore modeling; network pharmacology; artificial intelligence; molecular modeling; pharmaceuticals; agrochemicals; nutraceuticals; cosmetics
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Carbohydrate-Active Enzymes and Carbohydrate Engineering: From Mechanisms to Applications
edited by , Birte Svensson and
submission deadline 28 Feb 2027 | Viewed by 17 | Submission Open
Keywords: carbohydrate-active enzymes; enzyme discovery; enzyme mechanism; enzyme engineering; carbohydrate modification; structural analysis of carbohydrates; biomass conversion; enzymes applied in food, biotech and pharma industries
(This special issue belongs to the Section Chemical Biology)
Advanced Technologies for Water Pollution Control, 2nd Edition
edited by and
submission deadline 1 Mar 2027 | Viewed by 88 | Submission Open
Keywords: water pollution; advanced oxidation processes; membrane technologies; nanotechnology application; wastewater remediation; advanced technologies
(This special issue belongs to the Section Green Chemistry)
Innovative Chemical Pathways for CO2 Conversion, 2nd Edition
edited by and Juqin Zeng
submission deadline 1 Mar 2027 | Viewed by 53 | Submission Open
Keywords: CO2 conversion; CO2 utilization; carbon capture and utilization (CCU); CO2 reduction; carbon dioxide valorization; catalytic CO2 conversion; electrochemical CO2 reduction; photocatalytic CO2 conversion; thermocatalytic CO2 conversion; green chemistry; sustainable chemistry; carbon recycling; carbon neutrality; circular carbon economy; renewable energy; sustainable chemical processes; carbon-based fuels; value-added chemicals; climate change mitigation; CO2 emissions reduction; decarbonization; energy transition; life cycle assessment; process intensification
(This special issue belongs to the Section Green Chemistry)
Advanced Photo/Electrocatalysts for Energy Conversion and Environmental Applications, 3rd Edition
edited by and Dengrong Sun
submission deadline 10 Mar 2027 | 4 articles | Viewed by 3035 | Submission Open
Keywords: photocatalyst; electrocatalysis; nanostructured materials; surface/interface regulation; environment; energy
(This special issue belongs to the Section Photochemistry)
Emerging Trends in the Design and Functionality of Organic Dyes and Pigments
edited by Alina Raditoiu and
submission deadline 15 Mar 2027 | Viewed by 320 | Submission Open
Keywords: molecular design; functional colorants; sustainable dyes; natural colorants; eco-friendly pigments; photophysical properties; charge transfer mechanisms; textile functionalization; bio-based dyes; synthetic strategies; optical properties; photostability; dye-sensitized applications
(This special issue belongs to the Section Colorants)
Advances in Physical Chemistry: From Theory to Applications
edited by
submission deadline 15 Mar 2027 | Viewed by 285 | Submission Open
Keywords: electronic-structure theory; ultrafast spectroscopy; AI-driven modelling; energy-carrier dynamics; machine learning; medical physical chemistry; commercialization of physical chemistry
(This special issue belongs to the Section Physical Chemistry)
The Design and Synthesis of Nanomaterials for Electrochemical Energy Storage and Conversion
edited by Yan Zhou and Zhen Wu
submission deadline 16 Mar 2027 | 1 articles | Viewed by 1401 | Submission Open
Keywords: electrochemical energy storage; electrochemical energy conversion; batteries; supercapacitors; nanostructured electrode materials; nanostructured electrocatalysts
(This special issue belongs to the Section Applied Chemistry)
Advanced Biofuel Production submission deadline 30 Mar 2027 | 1 articles | Viewed by 680 | Submission Open
Keywords: biofuels; biomass conversion; catalysis; pyrolysis; synthetic fuels; waste to energy; renewable diesel; sustainable aviation fuel; hydrothermal liquefaction
(This special issue belongs to the Section Applied Chemistry)
Advances in Nanomaterials for Biomedical Applications, 2nd Edition
edited by Xueen Jia and Ce Zhang
submission deadline 31 Mar 2027 | 3 articles | Viewed by 9418 | Submission Open
Keywords: 2D nanomaterials; metal–organic frameworks (MOFs); metasurfaces; biosensor; drug delivery
(This special issue belongs to the Section Nanochemistry)
Wine Chemistry: From Flavor Profiling to Sensory Quality submission deadline 31 Mar 2027 | 3 articles | Viewed by 6771 | Submission Open
Keywords: wine; volatile organic compounds (VOCs); flavor; aroma; phenolic compounds; chemical composition; sensory; fermentation process
(This special issue belongs to the Section Flavours and Fragrances)
Unveiling the Applications of Bioactive Compounds in Functional Foods for Optimal Human Health—2nd Edition
edited by and
submission deadline 31 Mar 2027 | 4 articles | Viewed by 6733 | Submission Open
Keywords: functional foods; bioactive ingredients; health benefits; immune function; gut health; disease prevention
(This special issue belongs to the Section Food Chemistry)
Nutritional Properties, Sensory Profile and Bioactive Components of Food, 3rd Edition submission deadline 31 Mar 2027 | 5 articles | Viewed by 6487 | Submission Open
Keywords: food analysis; bioactive compounds; sensory characteristics; food composition; functional food ingredients
(This special issue belongs to the Section Food Chemistry)
Nanomaterials for Biomedicine: Innovations and Challenges
edited by and
submission deadline 31 Mar 2027 | 4 articles | Viewed by 6169 | Submission Open
Keywords: nanomaterial; targeted drug delivery; bio-imaging; antimicrobial application; cancer immunotherapy; nanovaccine
(This special issue belongs to the Section Nanochemistry)
Ionic Liquids and Molecular Materials: Advances in Functional Interfaces and Applications submission deadline 31 Mar 2027 | 5 articles | Viewed by 5908 | Submission Open
Keywords: ionic fluids; bulk properties; surface and interfacial properties; thin films; vacuum engineering; energy harvesting and storage; functional materials
(This special issue belongs to the Section Physical Chemistry)
Food Sustainability: Promising By-Products for Valorization—3rd Edition
edited by , Mihai Babotă and
submission deadline 31 Mar 2027 | 6 articles | Viewed by 5859 | Submission Open
Keywords: agri-food by-products; extraction and separation methods; functional bio-based ingredients; analytical chemistry; plant toxins; secondary metabolites; side-stream processing; biorefinery approaches
(This special issue belongs to the Section Food Chemistry)
Heterocycles: Design, Synthesis and Biological Evaluation, 4th Edition submission deadline 31 Mar 2027 | 3 articles | Viewed by 5766 | Submission Open
Keywords: heterocycles; organic synthesis; drug design; biological activity; medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Chemistry Applied to Enhanced Oil Recovery
edited by and Mingwei Gao
submission deadline 31 Mar 2027 | 4 articles | Viewed by 4317 | Submission Open
Keywords: advanced chemical materials for EOR; oil–gas field chemical working fluids; molecular engineering of EOR materials; reservoir chemical compatibility; chemical flooding enhancement mechanisms
(This special issue belongs to the Section Applied Chemistry)
Development of Computational Approaches in Chemical Biology
edited by , Dianyong Tang and Yichang Liu
submission deadline 31 Mar 2027 | 3 articles | Viewed by 4276 | Submission Open
Keywords: computational chemical biology; molecular modeling; molecular dynamics simulations; AI in drug discovery; protein–ligand interactions; protein design; biological networks; multi-omics integration
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Bioactive Components From Fungi in the Context of Biomedical Applications
edited by Magdalena Jaszek
submission deadline 31 Mar 2027 | 2 articles | Viewed by 3942 | Submission Open
Keywords: fungal bioactive substances; polysaccharides; phenolic compounds; mushroom extracts; medicinal mushrooms; biomedical applications; functional food
(This special issue belongs to the Section Natural Products Chemistry)
The Chemistry of Food Quality Changes During Processing and Storage
edited by
submission deadline 31 Mar 2027 | 4 articles | Viewed by 3877 | Submission Open
Keywords: innovative processing; microbiological quality; mitigation strategies; processing optimization; shelf life extension; physicochemical changes; nutritional value; antioxidant capacity
(This special issue belongs to the Section Food Chemistry)
Degradation of Aromatic Compounds in the Environment submission deadline 31 Mar 2027 | 2 articles | Viewed by 3572 | Submission Open
Keywords: aromatic compounds; microorganisms; biodegradation; biotransformation; advanced oxidation processes
(This special issue belongs to the Section Organic Chemistry)
Design and Preparation of New Metal Catalysts for Functional Organic Compounds Synthesis
edited by
submission deadline 31 Mar 2027 | 2 articles | Viewed by 3064 | Submission Open
Keywords: transition metal complexes; hybrid catalysts; nanocatalysts; single-atom catalysts; sustainable organic synthesis; natural products
(This special issue belongs to the Section Organometallic Chemistry)
Plant Bioactives in Human Health: From Phytochemistry to Molecular Mechanisms submission deadline 31 Mar 2027 | 2 articles | Viewed by 2989 | Submission Open
Keywords: bioactive compounds; bioavailability; extraction methods; biological activities; cell signalling; functional applications; nutraceuticals; human metabolism; toxicity; bioactive-gut microbiota relationships
(This special issue belongs to the Section Natural Products Chemistry)
Phytochemicals as Promising Molecules in Acute and Chronic Neurodegeneration
edited by
submission deadline 31 Mar 2027 | 1 articles | Viewed by 2934 | Submission Open
Keywords: phytochemicals; nutrients; morphology; transmission electron microscopy; autophagy; proteasome; neurodegeneration; central nervous system; peripheral nervous system; sensory organs
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Microplastics and Nanoplastics Analysis, 2nd Edition submission deadline 31 Mar 2027 | 4 articles | Viewed by 2826 | Submission Open
Keywords: microplastics; nanoplastics; monitoring; analytical methods; ecotoxicological assays
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in the Organic Synthesis of Bioactive Natural Compounds and Their Analogs submission deadline 31 Mar 2027 | 2 articles | Viewed by 2663 | Submission Open
Keywords: bioactive natural compounds; organic synthesis; natural products; synthetic methodologies; medicinal chemistry; drug discovery; total synthesis
(This special issue belongs to the Section Natural Products Chemistry)
Biological Activity of Metal Complexes: Design and Characterization Strategies submission deadline 31 Mar 2027 | 1 articles | Viewed by 2640 | Submission Open
Keywords: metal complexes; biological activity; metallodrugs; anticancer: antibacterial; antiviral; antiparasitic: delivery methods; biophysical characterization; DFT; docking
(This special issue belongs to the Section Inorganic Chemistry)
Rare Earth Luminescent Materials and Complexes: Structure, Properties and Applications
edited by , and Vladimira S. Videva
submission deadline 31 Mar 2027 | 1 articles | Viewed by 2531 | Submission Open
Keywords: rare earth elements; lanthanide complexes; luminescent materials; photophysical properties; upconversion; downshifting; coordination compounds; hybrid materials; optical materials; bioimaging; photonics; sensing; nanomaterials; structure–property relationships
(This special issue belongs to the Section Photochemistry)
Feature Papers in Food Chemistry—4th Edition
edited by
submission deadline 31 Mar 2027 | 6 articles | Viewed by 2514 | Submission Open
Keywords: food chemistry; functional food; ingredients; bioactivity; antioxidants; food safety and health; food processing
(This special issue belongs to the Section Food Chemistry)
Advances in Sustainable and Functional Bio-Based Porous Materials for Environmental Remediation
edited by and Yufei Nan
submission deadline 31 Mar 2027 | 2 articles | Viewed by 2192 | Submission Open
Keywords: bio-based materials; porous structure; adsorption of heavy metals/organics/dyes/microplastics; sustainable processing
(This special issue belongs to the Section Materials Chemistry)
Physicochemical Interactions and Modifications of Composition, Structure and Properties During Food Processing submission deadline 31 Mar 2027 | 2 articles | Viewed by 2134 | Submission Open
Keywords: phytochemicals; bioactive compounds; functional food; food processing
(This special issue belongs to the Section Food Chemistry)
Functional Nanomaterials and Composites: From Design Towards Energy & Environmental Applications submission deadline 31 Mar 2027 | 3 articles | Viewed by 1878 | Submission Open
Keywords: nanomaterials; composites; energy applications; environmental remediation; sustainable technologies
(This special issue belongs to the Section Nanochemistry)
Advances in the Mass Spectrometry of Chemical and Biological Samples, 2nd Edition
edited by
submission deadline 31 Mar 2027 | 2 articles | Viewed by 1871 | Submission Open
Keywords: sample preparation, extraction, and ionization techniques; targeted and untargeted MS-based methods; high-resolution mass spectrometry (HRMS); MS-based omics; MS imaging; MS-based biomarker discovery and clinical diagnosis; MS-based drug development and toxicity monitoring; MS-based analysis of microbiome; MS in food chemistry and control; MS in forensic science; MS in cosmetic science; MS in environmental science; miniature MS systems; MS applications in nanomaterials development; MS applications in synthetic chemistry
(This special issue belongs to the Section Analytical Chemistry)
Chemical and Physical Interactions Between Food and Packaging: Safety, Stability, and Quality submission deadline 31 Mar 2027 | 2 articles | Viewed by 1840 | Submission Open
Keywords: packaging; coating; physical properites; chemical properties; food quality; food safety
(This special issue belongs to the Section Food Chemistry)
Recent Advances in Antibacterial Nanomaterials
edited by
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1798 | Submission Open
Keywords: nanoparticles; biochemistry; antibacterial; bacteriostatic; cell membrane
(This special issue belongs to the Section Nanochemistry)
Extraction and Analysis of Natural Products in Food—4th Edition submission deadline 31 Mar 2027 | 3 articles | Viewed by 1774 | Submission Open
Keywords: natural products; extraction methodologies: green impacts and sustainability; separation and purification techniques; agri-food byproducts; natural bioactive compounds; food ingredients; industrial application
(This special issue belongs to the Section Natural Products Chemistry)
Metal Ions and Metal Complexes in Medicinal Chemistry submission deadline 31 Mar 2027 | 1 articles | Viewed by 1720 | Submission Open
Keywords: metal ions; metal complexes; synthesis; study; spectral analysis; biological activity; ligands
(This special issue belongs to the Section Medicinal Chemistry)
Bioactive Molecules for Targeted Cancer Therapy
edited by and Robert A. Falconer
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1605 | Submission Open
Keywords: enzymatic inhibitors; fragment-based discovery; chemical biology; covalent ligands; payloads; prodrug; (poly)peptide conjugates; antibody–drug conjugates; computational chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Chemistry, Bioactivity and Authenticity of Sugar-Rich and Fermented Foods and Beverages submission deadline 31 Mar 2027 | 3 articles | Viewed by 1512 | Submission Open
Keywords: sugar-rich foods; fermented beverages; chemical characterization; analytical techniques; bioactive compounds; metabolomics; authenticity; food control
(This special issue belongs to the Section Food Chemistry)
Advances in Phytochemical Analysis of Plant-Derived Bioactive Natural Products
edited by
submission deadline 31 Mar 2027 | 2 articles | Viewed by 1494 | Submission Open
Keywords: phytochemical analysis; plant-derived bioactive compounds; natural products chemistry; polyphenols; metabolite profiling; sustainable plant matrices; circular economy valorization; agro-industrial by-products; nutraceutical applications; structure–activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis, Properties, and Applications of Chiral Molecules
edited by José Luis Olivares-Romero
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1476 | Submission Open
Keywords: asymmetric catalysis; new chiral catalyst; stereoselective synthesis of natural products and analogs; chiral auxiliaries and reagents; computational and mechanistic studies of chiral processes; stereochemical characterization (e.g., ECD, VCD, NMR, XRD); chirality in pharmaceutical development (ADMET, enantioselective binding); enantioselective recognition, sensors, and separation technologies; chiral materials in optoelectronics, polymers, and supramolecular chemistry; green and sustainable strategies for chiral synthesis
(This special issue belongs to the Section Organic Chemistry)
Natural Pigments and Colorants in Food: Sources, Stability and Applications
edited by , Jarosław Wyrwisz, Małgorzata Moczkowska-Wyrwisz and Sabina Karp-Paździerska
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1422 | Submission Open
Keywords: natural colorants; anthocyanins; carotenoids; betalains; chlorophylls; encapsulation; stability; food applications; biopolymer interactions
(This special issue belongs to the Section Food Chemistry)
Development of Functional Hydrogels in Biomedicine
edited by
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1385 | Submission Open
Keywords: hydrogels; wound healing; biomaterials; nanotechnology; regenerative medicine; tissue regeneration
(This special issue belongs to the Section Medicinal Chemistry)
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