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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Development of Food Packaging Materials, 2nd Edition
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 786 | Submission Open
Keywords: plastics; glass; metals; paper/paperboard; biodegradable materials; recyclable materials; active and Intelligent materials; nanomaterials in packaging
(This special issue belongs to the Section Materials Chemistry)
Neurochemistry: Recent Advances and Future Opportunities in Antidepressants and Mood Stabilizers
edited by
submission deadline 31 Oct 2026 | Viewed by 260 | Submission Open
Keywords: neurochemistry; antidepressants; mood stabilizers; neurotransmitters; neuroplasticity; biomarkers; inflammation and mood disorders; personalized medicine; rapid-acting therapeutics; mechanisms of action
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Nanoscale Drug Delivery Technologies and Theranostics
edited by and Valérie Maraval
submission deadline 31 Oct 2026 | Viewed by 153 | Submission Open
Keywords: drug delivery; theranostics; nanoparticles; dendrimers; nanovesicle; nanomicelles; polymers; nanomaterials
(This special issue belongs to the Section Nanochemistry)
Exploration of Organometallic Materials and Beyond for Sustainable Energy Applications
edited by and
submission deadline 31 Oct 2026 | Viewed by 149 | Submission Open
Keywords: metal complex; metallated polymer; organometallic materials; non-fullerene acceptor; triplet exciton; charge transfer; organic optoelectronic devices; organic photovoltaics; thick-film solar cell
(This special issue belongs to the Section Materials Chemistry)
Targeting Cell Signaling Pathways in Drug Discovery
edited by
submission deadline 31 Oct 2026 | Viewed by 114 | Submission Open
Keywords: targeted therapy; non-communicable diseases; enzymes; synthetic compounds; natural extracts; molecular modeling; chemically modified drugs; cellular key targets
(This special issue belongs to the Section Chemical Biology)
Discovering the Pharmacological and Medicinal Potentials of Plant Flavonoids and Other Polyphenols from Nature submission deadline 31 Oct 2026 | Viewed by 109 | Submission Open
Keywords: flavonoids; polyphenols; natural product; anti-aging; anti-oxidative stress; anti-cancer; pharmacological activity; medical application
(This special issue belongs to the Section Natural Products Chemistry)
Featured Reviews on Bioactive Flavour and Fragrance Compounds, 2nd Edition
edited by
submission deadline 31 Oct 2026 | Viewed by 78 | Submission Open
Keywords: essential oils; agriculture; food; formulations; crop protection; insecticides; extraction techniques; chemical characterization; biological activity
(This special issue belongs to the Section Flavours and Fragrances)
Trends in Biosensors for Biomedical Applications submission deadline 31 Oct 2026 | Viewed by 71 | Submission Open
Keywords: optical biosensors (SPR; SERS; fluorescence; colorimetric); electrochemical biosensors; nanogravimetric biosensors; immunosensors; DNA-based biosensors; aptamer-based biosensors; exosomal biomarkers; enzymatic-biosensors
(This special issue belongs to the Section Chemical Biology)
Starch: Chemistry, Technology, and Application—2nd Edition
edited by
submission deadline 31 Oct 2026 | Viewed by 69 | Submission Open
Keywords: starch modification; starch complexes; resistant starch; digestibility; precision nutrition; green technology; structure– function relationship
(This special issue belongs to the Section Food Chemistry)
Featured Review in Wine Chemistry submission deadline 31 Oct 2026 | Viewed by 58 | Submission Open
Keywords: wine chemistry; review; wine flavors; polyphenols; sensory; analytical techniques
(This special issue belongs to the Section Flavours and Fragrances)
Phytochemicals and Their Anti-Inflammatory and Antioxidant Properties submission deadline 31 Oct 2026 | Viewed by 57 | Submission Open
Keywords: bioactive components; plant extracts; functional food; polyphenols; carotenoids; organic acids; vitamins
(This special issue belongs to the Section Natural Products Chemistry)
Computational Approaches for Drug and Protein Design submission deadline 31 Oct 2026 | Viewed by 52 | Submission Open
Keywords: computational drug design; molecular docking and molecular dynamics simulations; generative-AI and machine learning in drug discovery; protein structure prediction; ligand-based/structure-based drug discovery; biomolecular modelling
(This special issue belongs to the Section Computational and Theoretical Chemistry)
New Research on Novel Photo-/Electrochemical Materials—2nd Edition
edited by and
submission deadline 31 Oct 2026 | Viewed by 51 | Submission Open
Keywords: photo-/electrochemistry; water splitting; fuel cell; zinc air battery; nitrogen reduction reaction; CO2 reduction reaction; photocatalytic degradation; gas sensor
(This special issue belongs to the Section Materials Chemistry)
Research Progress of New Antimicrobial Drugs—2nd Edition submission deadline 31 Oct 2026 | Viewed by 51 | Submission Open
Keywords: synthesis of new antimicrobials; bioactive compounds; antimicrobial derivatives; synthetic and natural compounds; pathogens and opportunistic microbes; prevention and treatment; antibiofilm; discovery of antimicrobials
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Nanocomposites and Functional Textiles for Environmental and Biomedical Applications
edited by
submission deadline 31 Oct 2026 | Viewed by 45 | Submission Open
Keywords: nanocomposites; functional textiles; smart and responsive materials; electrospinning and advanced fabrication; green nanomaterials; environmental remediation; antimicrobial and biocompatible fabrics; wearable and biomedical textiles; energy harvesting and sensing applications; sustainable textile engineering
(This special issue belongs to the Section Materials Chemistry)
Intramolecular Hydrogen Bonds
edited by
submission deadline 31 Oct 2026 | Viewed by 38 | Submission Open
Keywords: intramolecular hydrogen bonds; intramolecular proton transfer; charge-assisted hydrogen bonding; molecular conformation; supramolecular chemistry
(This special issue belongs to the Section Physical Chemistry)
Recent Advances in Biocatalysis submission deadline 31 Oct 2026 | Viewed by 37 | Submission Open
Keywords: enzymatic cascade reactions; artificial metabolism and minimal systems; hybrid chemoenzymatic catalysis; enzyme immobilization and nanostructured supports; sustainable and green biocatalysis
(This special issue belongs to the Section Bioorganic Chemistry)
Photobiology: Bioactive Compounds of Plants in Response to Light Conditions submission deadline 31 Oct 2026 | Viewed by 34 | Submission Open
Keywords: light-dependent reactions; photoprotective substances; bioactive compounds; natural product engineering tool; response to light conditions
(This special issue belongs to the Section Photochemistry)
Metal Complexes and Their Medicinal Applications
edited by
submission deadline 15 Nov 2026 | Viewed by 50 | Submission Open
Keywords: metal complexes; medicinal chemistry; anticancer agents; antimicrobial activity; diagnostic imaging; therapeutic design; coordination chemistry; supplements; clinical dietetics
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Alkyne Chemistry
edited by Ruimao Hua
submission deadline 25 Nov 2026 | 7 articles | Viewed by 33330 | Submission Open
Keywords: alkyne annulation; carbocycle synthesis; heterocycle synthesis; atom-economic reaction; synthesis methodology
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Materials Chemistry
edited by , and Mu-Ping Nieh
submission deadline 30 Nov 2026 | 11 articles | Viewed by 19699 | Submission Open
Keywords: materials chemistry; synthetic procedures; characterization procedures; nanomaterials and nanocomposites; biologically oriented materials and biomaterials; materials of natural origin; hybrid composites; mechanical properties; long-term durability
(This special issue belongs to the Section Materials Chemistry)
Heterophase Polymerization and Functional Polymer Microspheres/Microcapsules
edited by Chengyou Kan and Wei Deng
submission deadline 30 Nov 2026 | 6 articles | Viewed by 12994 | Submission Open
Keywords: emulsion polymerization; mini emulsion polymerization; dispersion polymerization; suspension polymerization; encapsulation; functionalization; polymer microspheres; microcapsules; characterization; morphology control; structure– property relationship; polymer nanocomposite; application
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules—Recent Advances in Computational and Theoretical Chemistry
edited by
submission deadline 30 Nov 2026 | 8 articles | Viewed by 9592 | Submission Open
Keywords: computational chemistry; quantum chemistry; density functional theory; molecular design; reaction mechanism; chemical bonding; non-covalent interactions; molecular docking
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Physical–Chemical Interactions and Composition–Structure–Property Modifications During Food Processing submission deadline 30 Nov 2026 | 1 articles | Viewed by 1479 | Submission Open
Keywords: structure; food; thermal properties; chemical composition
(This special issue belongs to the Section Food Chemistry)
Natural Bioactive Compounds: Antioxidant Properties and Associated Biological Activities
edited by
submission deadline 30 Nov 2026 | Viewed by 256 | Submission Open
Keywords: natural compounds; bioactive compounds; antioxidant activity; biological activities; chemical analysis; structure-function relationships; advanced extraction methods
(This special issue belongs to the Section Natural Products Chemistry)
Recent Advances in Medicinal Chemistry in Asia
edited by and Jinfei Yang
submission deadline 30 Nov 2026 | Viewed by 209 | Submission Open
Keywords: drug design; drug discovery; lead compounds; anticancer agents; antiviral agents; antidiabetic agents; CNS agents
(This special issue belongs to the Section Medicinal Chemistry)
Current Development Prospects of Novel Nanocatalysts
edited by Fengyu Gao
submission deadline 30 Nov 2026 | Viewed by 159 | Submission Open
Keywords: novel nanocatalysts; pollutant purification; environmental catalysis technology; precious metals; metal/alloys; metal oxides; non-metallic materials; environmental protection; gas purification; wastewater treatment; soil remediation; solid waste management; carbon neutrality
(This special issue belongs to the Section Green Chemistry)
Organic Supramolecular Nanomaterials in Biomedical Applications: Design, Synthesis, Assembly, and Property Regulation
edited by
submission deadline 30 Nov 2026 | Viewed by 52 | Submission Open
Keywords: supramolecular nanobiomaterials; biomedical applications; organic supramolecular chemistry; polymer synthesis; bioimaging and biosensing; organic– inorganic hybrid nanomaterials
(This special issue belongs to the Section Organic Chemistry)
Bioactive Compounds in Food and Plants: Phytochemical Analysis, Structural Elucidation, Biological Properties and Therapeutic Potential submission deadline 30 Nov 2026 | Viewed by 44 | Submission Open
Keywords: medicinal plants; food; food waste; plant by-products; bioactive metabolites and lipids; NMR spectroscopy; mass spectrometry; biological activity
(This special issue belongs to the Section Natural Products Chemistry)
The 30th Anniversary of Molecules—Recent Advances in Nanochemistry
edited by
submission deadline 30 Nov 2026 | Viewed by 43 | Submission Open
Keywords: nanochemistry; nanoscale materials; nanocrystals; nanostructures; nanotubes; nanofabrication; nanomedicine; metal nanoparticles
(This special issue belongs to the Section Nanochemistry)
Biological Properties of Extracts and Essential Oils from Plants of the Lamiaceae Family: An Updated Perspective submission deadline 30 Nov 2026 | Viewed by 37 | Submission Open
Keywords: lamiaceae family; essential oils; plant extracts; secondary metabolites; bioactive properties; anti-inflammatory
(This special issue belongs to the Section Natural Products Chemistry)
Recent Progress in Theoretical and Experimental Chemical Thermodynamics
edited by
submission deadline 30 Nov 2026 | Viewed by 36 | Submission Open
Keywords: chemical thermodynamics; theoretical innovation; experimental methods; characterization techniques; multi-scale simulation
(This special issue belongs to the Section Physical Chemistry)
Research Advances on New Drugs and Drug Targets in Melanoma
edited by Paula Wróblewska-Łuczka
submission deadline 30 Nov 2026 | Viewed by 29 | Submission Open
Keywords: melanoma; new drugs; drug targets; mechanism of action; substances with anti-melanoma potential
(This special issue belongs to the Section Chemical Biology)
Bioactive Components in Plants: Extraction, Characterization and Antioxidant Activity
edited by
submission deadline 15 Dec 2026 | Viewed by 82 | Submission Open
Keywords: bioactive compounds; plant extracts; extraction of bioactives; polyphenols; chemical characterization; antioxidant activity; green chemistry
(This special issue belongs to the Section Natural Products Chemistry)
Characterization of Organic Ligands: Correlations Between Results by Electrochemistry and Other Methods
edited by Eleonora-Mihaela Ungureanu
submission deadline 20 Dec 2026 | 1 articles | Viewed by 853 | Submission Open
Keywords: connections; electrochemical experiments; characterization of organic ligands; DFT calculations of ligand properties; optical methods; electrochemical methods; surface characterization methods (SEM; AFM; Raman; etc.); analytical methods
(This special issue belongs to the Section Applied Chemistry)
30th Anniversary of Molecules: Recent Advances and the Next in Macromolecular Chemistry submission deadline 31 Dec 2026 | 8 articles | Viewed by 17756 | Submission Open
Keywords: macromolecular chemistry; synthetic polymers; natural polymers; polymerization mechanisms and kinetics; supramolecular self-assembly; biological macromolecules
(This special issue belongs to the Section Macromolecular Chemistry)
30th Anniversary of Molecules—Recent Advances in Organic Chemistry
edited by , Antonia Di Mola and
submission deadline 31 Dec 2026 | 10 articles | Viewed by 15412 | Submission Open
Keywords: organic synthesis; organic chemistry research; theoretical study; reaction mechanisms; catalysis
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Chemical Biology submission deadline 31 Dec 2026 | 6 articles | Viewed by 15361 | Submission Open
Keywords: bioorthogonal chemistry; peptides; nucleic acids; proteins; analytical methods; chemical inhibitors; chemical probe; ubiquitination; structure-activity relationship
(This special issue belongs to the Section Chemical Biology)
30th Anniversary of Molecules—Recent Advances in Inorganic Chemistry submission deadline 31 Dec 2026 | 9 articles | Viewed by 10588 | Submission Open
Keywords: inorganic chemistry; coordination chemistry; solid-state chemistry; nanomaterials; organometallics; transition and main group metal chemistry; catalysis; bioinorganic chemistry
(This special issue belongs to the Section Inorganic Chemistry)
The 30th Anniversary of Molecules—Recent Advances in Natural Products Chemistry submission deadline 31 Dec 2026 | 5 articles | Viewed by 8364 | Submission Open
Keywords: natural compounds; bioactive molecules; drug discovery; pharmacological activity; formulations; drug delivery systems; food applications and additives; cosmetic applications; synthesis
(This special issue belongs to the Section Natural Products Chemistry)
30th Anniversary of Molecules—Recent Advances in Analytical Chemistry submission deadline 31 Dec 2026 | 3 articles | Viewed by 5855 | Submission Open
Keywords: chromatography and advanced mass spectrometry; atomic spectroscopy and elemental mass spectrometry; molecular spectroscopy; miniaturization of analytical instruments; ohmics; nanomaterials and sensors; automation and high-throughput screening; single-cell analysis; non-invasive analysis/techniques; green analytical chemistry
(This special issue belongs to the Section Analytical Chemistry)
30th Anniversary of Molecules: Recent Advances in Photochemistry submission deadline 31 Dec 2026 | 3 articles | Viewed by 3466 | Submission Open
Keywords: organic photochemistry synthetic photochemistry; photocatalysis; photofunctionalization; photobiology; medicinal photochemistry; computational photochemistry; photoelectrochemistry; solar energy conversion; condensed and gas phase photochemistry; polymer photochemistry; supramolecular photochemistry; photochromism; luminescent sensors; photochemistry for environmental remediation
(This special issue belongs to the Section Photochemistry)
Modern Trends and Solutions in Analytical Chemistry in Poland
edited by
submission deadline 31 Dec 2026 | 4 articles | Viewed by 3337 | Submission Open
Keywords: analytical and physical chemistry; separation sciences; chromatographic methods and related techniques (HPLC; SPE; SFC; GC; CZE; UPLC; GC × GC; and others); sample preparation and extraction techniques (SPE; QuEChERS/d-SPE; SPME; SBSE; HFLPME; DLLME; FUSLE; and others); detection techniques (DAD; FLD; MS; MS/MS; and others); spectrometry; bioanalytics; proteomics; metabolomics; and lipidomics; nanotechnology; environmental sciences; natural product chemistry (isolation; identification and quantification of bioactive compounds; and in vitro and then in vivo investigations on their biological activity); food analysis and food safety; xenobiotics analysis in environmental; biological; and food samples; chemometrics and statistical analysis
(This special issue belongs to the Section Analytical Chemistry)
30th Anniversary of Molecules—Recent Developments in Biobased Polymers submission deadline 31 Dec 2026 | 3 articles | Viewed by 3315 | Submission Open
Keywords: biobased polymers; sustainability; biodegradability; polymer recycling; polymer composites; polymer processing; green chemistry
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules: Recent Advances in Organometallic Chemistry
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2672 | Submission Open
Keywords: metal– organic framework; organometallic compounds; coordination assembly; metal– organic cluster; metal– organic cage; supramolecular chemistry
(This special issue belongs to the Section Organometallic Chemistry)
Recent Advances in Peptide Assembly and Bioactivity
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1176 | Submission Open
Keywords: peptide; self-assembly; co-assembly; stimuli-responsive; bioactivity; biomaterials
(This special issue belongs to the Section Bioorganic Chemistry)
Silymarin and Derivatives: From Biosynthesis to Health Benefits 2.0
edited by
submission deadline 31 Dec 2026 | Viewed by 636 | Submission Open
Keywords: silymarin: sources and biosynthesis; secondary metabolites and silymarin derivatives; silymarin bioavailability; silymarin and cardiovascular diseases; silymarin and metabolic syndrome; silymarin and cancer; silymarin and inflammation and immune diseases; silymarin and degenerative age-related diseases
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Lactam Chemistry: From Synthetic Strategies to Biological Applications
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 537 | Submission Open
Keywords: lactams; sustainable synthesis; structure– activity relationship (SAR); drug discovery; β -lactam analogues; heterocyclic chemistry; therapeutic applications; antimicrobial and anticancer agents
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Electrochemistry
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 475 | Submission Open
Keywords: electrochemical science; energy conversion; charge transfer; voltammetry; magnetoelectrochemistry/spin; redox chemistry
(This special issue belongs to the Section Electrochemistry)
Metal–Halide Perovskites for Solar Cell and LED Materials
edited by
submission deadline 31 Dec 2026 | Viewed by 409 | Submission Open
Keywords: hybrid halide perovskite solar cell materials; perovskite light-emitting diode materials; optical properties; luminescence; material property characterization; thin solid films; crystal formation
(This special issue belongs to the Section Materials Chemistry)
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