Fluorescent Probes in Pharmaceutical and Drug Design Applications: Quantum Chemistry-Based Design, Synthesis, Photophysical and Chemical Properties, Biological Applications

Dear Colleagues,

The need for ultra-sensitive ultra-fast highly specific monitoring of biological processes or trace levels of endogenous substances or xenobiotics and toxicants has forcefully pushed the frontiers of fluorescence-based probe science towards novel approaches. The developments in instrumentation as in fluorescence microscopy or LIF, as well as methodological approaches such as FRET, time-resolved fluorescence, or immunofluorescence, proved that fluorescence has unlimited potential to reveal “difficult” to follow biological processes. In contrast, new developments in fluorescence-aided chromatographic science have enabled the precise mapping of target substance distribution in the human body. This Special Issue will collect recent advances in the exciting field of fluorescence probes that span over quantum-chemistry or molecular modeling-based design, synthetic approaches, and their application in biological phenomena. The contributions will be focused on the pharmaceuticals/drugs filed, including applications for API/impurity/degradation product detection, bioavailability/pharmacodynamics methodologies, receptor probes, cellular enzymatic reactions monitoring, organelle targeting probes, and any other application related to the modulating or probing processes of the human body.

Dr. Ioannis Kostakis
Prof. Dr. Evagelos Gikas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.