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Special Issue "Endocannabinoid System Modulators in a Medicinal Chemistry Perspective"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 31 May 2020

Special Issue Editors

Guest Editor
Prof. Dr. Alessandra Bisi

Department of Pharmacy and Biotechnology, Alma Mater Studiorum—University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy
Website | E-Mail
Interests: flavonoids; hybrid molecules; privileged structures; MDR reversal; cytochromes P-450 inhibitors; Alzheimer’s disease; CB receptor ligands
Guest Editor
Prof. Dr. Angela Rampa

Department of Pharmacy and Biotechnology, Alma Mater Studiorum—University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy
Website | E-Mail
Interests: drug design; hybrid molecules; Alzheimer’s disease; AChE inhibitors; FAAH inhibitors; CB receptors ligands; flavonoids

Special Issue Information

Dear Colleagues,

Currently, the term “endocannabinoid system” (ECS) includes endogenous cannabinoids (endocannabinoids, mainly anandamide and 2-arachidonoylglycerol), the enzymes involved in their biosynthesis, transport and degradation and the G protein-coupled receptors (cannabinoid receptors, CBRs) with which they interact. In recent years, it has become clear that the ECS is up-regulated in numerous pathophysiological states such as inflammatory, neurodegenerative, gastrointestinal, metabolic and cardiovascular diseases, pain and cancer, and that its modulation offers significant potential for intervention in different areas of human health. This Special Issue aims to provide an overview of the latest studies on potential drugs acting on this challenging system, both involving the cannabinoid receptors and/or the enzymes responsible for endocannabinoids transport and hydrolysis, recognized as validated targets in medicinal chemistry.

Prof. Dr. Alessandra Bisi
Prof. Dr. Angela Rampa

Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • CB ligands
  • FAAH inhibitors
  • MAGL inhibitors
  • Reuptake inhibitors
  • Neurodegeneration
  • Pain
  • Cancer

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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