Cellular and Molecular Bioengineering

Dear Colleagues,

The field of cellular and molecular engineering aims to improve human health by researching cellular behaviors driven by interactions at the molecular level, using engineering principles and methods to provide technological solutions for a complete knowledge of the mechanisms.

With the convergence of the fields of engineering and cell and molecular biology, new directions have emerged for pathogenesis studies. Abnormalities in cellular processes, such as adhesion, migration, differentiation, proliferation, protein secretion, gene expression and regulation and apoptosis, can be detected owing to the recent advances in modern bioengineering tools. Additionally, cell–cell and cell–ECM interactions and cell signaling, which are the main directing mechanisms in both health and disease, can be analyzed and reproduced for various biomedical applications. The principles and techniques of bioengineering have led to progress in our understanding the molecular-level interactions, and their influence on cell, tissue, and organ behaviors.

The rise of cellular and molecular engineering is the result of the merged research of engineers, biologists, physicists, and chemists that have tried to solve fundamental and urgent problems in medicine, public health, and biology.

Cellular and molecular engineering have also led to groundbreaking advances in the field of translational medicine, with an emphasis on disease-specific biomarkers, molecular imaging, micropatterning, and applied immunology, which can further improve the outcomes of clinical research.

Topics:

• Engineering cell and tissue microenvironment
• Cell and molecular mechanics
• Membrane biochemistry and biophysics
• Molecular dynamics
• Cellular networks modeling
• Protein engineering and metabolism
• Biomolecules manufacturing
• Biophysical and biochemical signals
• ECM-inspired biomaterial design
• Bioengineered enzymes

Assoc. Prof. Dr.  Alexandru Mihai Grumezescu
Guest Editor

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