Chemistry and Biochemistry of Cellular Thiols

Dear Colleagues,

Following the success of the SI (Special Issue) "Glutathione: Chemistry and Biochemistry", we are pleased to launch a new SI titled "Chemistry and Biochemistry of Cellular Thiols". Cellular thiols play an essential role in a multitude of cellular processes, including redox homeostasis, cell cycle control, immunological defense, and pathological abnormalities. Besides glutathione, the well-known antioxidant cytosolic tripeptide, there are several enzymes, transcription factors and signaling proteins with reactive thiol functions. The reactive thiol functions of these cellular macromolecules play important roles in the maintenance of healthy cellular functions and development of particular diseases.

This Special Issue will publish research papers and review articles that include the widest range of chemical and biochemical changes related to cellular thiols. Papers that discuss any aspect of the complex thiol-based redox homeostasis as well as drug delivery systems that can be applied to efficiently increase or decrease cellular glutathione levels are all welcome. The aim of this compilation is to collect up-to-date knowledge of our understanding of the roles of the thiol network in the homeostasis of the living state of matter. From a medicinal chemistry point of view, submissions on any type of intervention of modification of functions of the network are also welcome.

According to the above set aims, I wish to ask all researchers who know the field and who are active practitioners of any segment of the field to participate in this endeavor.

Prof. Dr. Pál Perjési
Guest Editor

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