Synthesis of Organic Ligands and Their Metal Complexes in Medicinal Chemistry—2nd Edition

Dear Colleagues,

The application of organic, bioinorganic, and coordination chemistry to medicine is a rapidly developing field, and novel therapeutic and diagnostic organic ligands and metal complexes are now impacting medical practice. Much attention has been focused on designing new coordination compounds with improved pharmacological properties and a broader range of activity. The application of new methodologies such as theoretical approaches, extensively used in drug discovery, is beneficial for the development of biologically active organic ligands and their coordination complexes as therapeutics.

The Special Issue, entitled “Synthesis of Organic Ligands and Their Metal Complexes in Medicinal Chemistry—2nd Edition”, will focus on recent advances in developing organic and metal-based agents, with an emphasis on synthesis, theoretical, analytical and physicochemical characterization, properties, and application. It will be mainly focused on recent efforts to prepare novel metal complexes and review some mechanistic insights into the pharmacological effects of these complexes, which is crucial to their clinical success, as well as to the rational design of new compounds with improved potency. This Special Issue will review this exciting field of medicinal chemistry and discuss current design rules and methods for synthesis, characterization and drug discovery strategies. Papers may cover the following: theoretical analyses, modelling, experimental studies on synthesis and characterization of biologically active compounds, and pharmacological investigations. The goal of the Special Issue is to present up-to-date information on and recent advances in varied aspects of this area of research. Original research articles, short communications, and reviews in medicinal chemistry highlighting the latest developments in the field will be considered for publication.

Dr. Alessia Catalano
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.