Recent Progress in Biocatalysis and Enzyme Engineering for Manufacturing Pharmaceutical Intermediates

Dear Colleagues,

Biocatalysis is a benign approach to replace and expand traditional organic synthesis due to its high efficiency, excellent selectivity and mild reaction conditions. Enzyme engineering enables one to adapt catalyst to the desired reaction and process. Recently, various strategies to adapt enzymes for use as catalysts for efficient biocatalysis, such as chemical modification, immobilization, site-directed mutagenesis, directed evolution of enzymes, computational design, substrate engineering and medium engineering, have been successfully developed. Novel biocatalysts and bioprocesses have been effectively utilized for the production of value-added pharmaceutical intermediates for human society.

This Special Issue aims to showcase advancements in biocatalysis and enzyme engineering to enhance their efficiency, specificity and stability in a benign bioreaction system. Original research papers and reviews focused on the frontiers of biocatalysis and enzyme engineering are collected in this Special Issue. Other submissions are also welcome from outside the areas presented above.

Prof. Dr. Yu-Cai He
Dr. Wei Tang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.