Epidemiology of Geriatric Syndromes: Life Course Risk or Protective Factors

A special issue of Medicina (ISSN 1648-9144).

Deadline for manuscript submissions: closed (25 October 2025) | Viewed by 1293

Special Issue Editor


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Guest Editor
Behavioral Science and Health Education, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida Agricultural and Mechanical University, Tallahassee, FL, USA
Interests: geriatric syndromes; gerontology/aging; public health/ epidemiology; preventive medicine; global health and cancer; health disparities; spirituality; adverse childhood experiences; abuse; discrimination

Special Issue Information

Dear Colleagues,

I am delighted to serve as the Guest Editor of this Special Issue about geriatric syndromes related to life course risk or protective factors. A Special Issue is not an issue of the journal. All submissions follow the same peer review process as regular papers and are published in the journal’s regular issues when accepted. However, they are additionally labeled as belonging to a Special Issue and are discoverable within the collection. A Special Issue with more than ten articles can be published as a dedicated e-book.

Early life exposures (prenatal, childhood, youth, or early adulthood), a mix of physical and psychosocial factors (modifiable and non-modifiable), may determine the long-term development of physical and mental diseases or affect aging. These exposures include traumatic or stressful life events, adverse childhood experiences, deprivation, or adversity in social determinants of health. Many studies have focused on youth or adulthood, but fewer studies have focused on exposure consequences for middle-aged or older people. Potential risk factors include chronic stress, environmental or neighborhood exposures, socioeconomic adversity, isolation, abuse, and discrimination. Potential protective factors include exercise, a healthy diet, adequate sleep, social support, social participation, resilience, and spirituality. In theory, all later-life diseases or geriatric syndromes might be associated with early-life exposures. These syndromes include frailty, sarcopenia, multimorbidity, falls, fear of falling, sleep disorders, cognitive decline, delirium, post-traumatic stress disorder, chronic pain, depressive disorders, and functional decline. However, early life exposures could also determine the onset or worsening of chronic diseases, such as cardiovascular diseases (stroke, heart disease), hypertension, diabetes, or cancer, as the leading causes of death in middle-aged or older populations around the world. They may also determine risky behaviors (alcohol, smoking, or others). Alternatively, early life exposures may determine quality-of-life measures, such as sexual life, self-rated health, or spiritual life.

This Special Issue aims to identify early life exposures as risk and protective factors determining health outcomes later in life, focusing on the development of the association with geriatric syndromes or chronic diseases. The broad scope of this Special Issue aims to encourage the coverage of a wide range of potential factors related to the development of geriatric syndromes or chronic diseases worldwide. Articles may be original research (quantitative, qualitative), reviews (comprehensive reviews and systematic reviews), or case reports.

Dr. Carlos Alfonso Reyes-Ortiz
Guest Editor

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Keywords

  • older adults
  • geriatric syndromes
  • chronic disease
  • early life adversity
  • adverse childhood experiences
  • risk factors
  • protective factors

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Published Papers (1 paper)

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Research

12 pages, 937 KB  
Article
Inactivity and Sitting Time in Later Life: A Saudi National Profile and Policy Implications for Vision 2030
by Saad M. Bindawas
Medicina 2025, 61(12), 2095; https://doi.org/10.3390/medicina61122095 - 25 Nov 2025
Viewed by 597
Abstract
Background and Objectives: Saudi Arabia’s aging population faces significant challenges from physical inactivity and prolonged sedentary behavior. This study quantified the prevalence of physical inactivity and sedentary behavior among older adults (aged 65 years and above) compared with those aged 55–64 years. Materials [...] Read more.
Background and Objectives: Saudi Arabia’s aging population faces significant challenges from physical inactivity and prolonged sedentary behavior. This study quantified the prevalence of physical inactivity and sedentary behavior among older adults (aged 65 years and above) compared with those aged 55–64 years. Materials and Methods: We conducted a secondary analysis of data from the 2013 Saudi Health Interview Survey. The analysis focused on adults aged 55–64 years and those aged 65 years and older, stratified by sex. Physical inactivity was defined as <150 min of moderate-to-vigorous activity per week, and sedentary behavior as ≥6 h per day sitting or screen time. Results: Among adults ≥65 years (n = 875; 517 men, 358 women), 70.6% of women (95% CI 63.4–77.8) and 37.9% of men (95% CI 32.3–43.5) were inactive (difference: 32.7 percentage points). 42.7% of women (95% CI, 34.7–50.7%) and 32.0% of men (95% CI, 26.3–37.7%) reported ≥6 h of daily sitting. From ages 55–64 to ≥65, inactivity increased by 16.4 percentage points in women and 10.7 percentage points in men, while sitting increased by 9.5 percentage points and 8.5 pp, respectively. Conclusions: Older Saudi adults, especially women, face significant challenges related to physical inactivity and sedentary lifestyles, particularly after age 65. Addressing these issues through gender-responsive policies and interventions is vital for promoting health as part of Saudi Vision 2030. Full article
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