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Medicina
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State-of-the-Art Therapeutics and Imaging in Knee Surgery
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State-of-the-Art Therapeutics and Imaging in Knee Surgery

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Surgery".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 883

Special Issue Editors

Dr. Cristian Scheau

E-Mail Website
Guest Editor
Department of Physiology, The “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: physiology; inflammation; carcinogenesis; medical imaging; transplantation; molecular signaling; MR spectroscopy
Special Issues, Collections and Topics in MDPI journals
Dr. Romica Cergan

E-Mail Website
Guest Editor
Department of Anatomy, The “Carol Davila” University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, 050474 Bucharest, Romania
Interests: anatomy; medical imaging; orthopaedics; anatomical variants; radiology; computed tomography; trauma; staging
Special Issues, Collections and Topics in MDPI journals
Dr. Serban Dragosloveanu

E-Mail Website
Guest Editor Assistant
Department of Orthopaedics and Traumatology, The “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: orthopaedic surgery; arthroplasty; arthroscopy; robotic surgery; rehabilitation; orthopedic infections; trauma; surgical reconstruction

Special Issue Information

Dear Colleagues,

This Special Issue aims to unite the latest/most advanced research and clinical practices that are transforming the field of knee surgery. We invite papers that explore innovative therapeutic approaches and advanced imaging techniques. The topics of interest include, but are not limited to, minimally invasive surgical techniques, regenerative medicine, novel pharmacological treatments, novel surgical approaches and the latest updates in diagnostic imaging modalities such as MRI, CT and ultrasound. We have a particular interest in studies that demonstrate how these advancements are improving patient outcomes, reducing recovery times, and enhancing the precision and efficacy of knee surgeries. Join us in advancing the future of knee surgery through the integration of state-of-the-art therapeutics and medical imaging techniques.

Dr. Cristian Scheau
Dr. Romica Cergan
Guest Editors

Dr. Serban Dragosloveanu
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • knee surgery
  • minimally invasive techniques
  • regenerative medicine
  • diagnostic imaging modalities
  • MRI in knee surgery
  • CT and ultrasound imaging
  • novel surgical approaches
  • pharmacological treatments
  • patient outcomes
  • precision surgery
  • state-of-the-art therapies
  • clinical advancements
  • surgical precision
  • efficacy of knee treatments
  • robotic knee surgery
  • surgery-related costs
  • 3D-printing in knee surgery
  • novel surgical biomaterials
  • anatomical landmarks
  • knee morphometry

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

15 pages, 2609 KiB  
Article
Venous Thromboembolism Prophylaxis in Hemophilic Patients Undergoing Total Hip or Knee Arthroplasty: Insights from a Single-Center Experience
by Oana-Viola Badulescu, Paul-Dan Sirbu, Manuela Ciocoiu, Maria Cristina Vladeanu, Carmen Elena Plesoianu, Andrei Bojan, Dan Iliescu-Halitchi, Razvan Tudor, Bogdan Huzum, Mihnea-Theodor Sirbu, Norin Forna, Gheorghe Sofron, Wilhelm Friedl and Iris Bararu-Bojan
Medicina 2025, 61(4), 570; https://doi.org/10.3390/medicina61040570 - 22 Mar 2025
Viewed by 249
Abstract
Background and Objectives: Total hip replacement and total knee arthroplasty carry a high risk of postoperative venous thromboembolism (VTE); therefore, anticoagulation prophylaxis is recommended in these patients. Unfortunately, there are no guidelines about VTE prophylaxis in patients with hemophilia who underwent these [...] Read more.
Background and Objectives: Total hip replacement and total knee arthroplasty carry a high risk of postoperative venous thromboembolism (VTE); therefore, anticoagulation prophylaxis is recommended in these patients. Unfortunately, there are no guidelines about VTE prophylaxis in patients with hemophilia who underwent these high-risk surgeries. To determine whether these patients have a high risk of VTE, we conducted a retrospective study on patients with hemophilia who underwent elective arthroplasty at our hospital in 2016. Materials and Methods: There were 11 patients with hemophilia A and B who underwent high-risk surgeries. Recombinant factor VIII or IX and also active recombinant Factor VII were used for perioperative hemostasis, and LMWH was administered for thromboembolic prophylaxis. Postoperatively, we collected information on the duration of factor VIII/IX infusion, VTE-prophylaxis, and complications. Results: Postoperative bleeding was minimal in most cases, with an average blood loss of 500 mL. No major thrombotic events were reported, and the need for transfusion was low, with only one patient requiring additional blood products. The VTE prophylaxis included prophylactic enoxaparin and hemostatic treatment. At the 1-year follow-up, we did not find any evidence of clinical VTE in our patients. Conclusions: Better risk stratification is needed to identify patients who would benefit from pharmacological prophylaxis. Total arthroplasty in hemophilic patients is feasible and safe when managed by a multidisciplinary team and supported by tailored antithrombotic prophylaxis protocols. The use of recombinant coagulation factors and LMWH ensures effective bleeding control and thromboembolic prevention, enhancing patient outcomes. These findings underscore the importance of individualized care in this high-risk population. Full article
(This article belongs to the Special Issue State-of-the-Art Therapeutics and Imaging in Knee Surgery)
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