Biomaterials for Cancer Therapy

Dear Colleagues,

Cancer is the second leading cause of death in the world; therefore, diagnosis and therapy of the various types of cancers are of utmost importance in the biomedical field. Up to now, a huge number of chemicals and drugs in various forms have been designed and developed to treat cancer, and several commercially-available products are currently being used in clinics. In this regard, chemo-radiotherapy, targeted therapies, immunotherapy, and combination therapies are commonly carried out in clinics; furthermore, the use of advanced organic and inorganic implantable/injectable biomaterials offers new opportunities for improved cancer treatment.

Possibilities in materials-regulated cancer diagnosis and therapy are actually considerable; various formulations of materials could be utilized in a broad range of shapes and structures both in bare and functionalized forms. Some types of biomaterials are capable of intrinsically acting as anticancer agents, while others can be used as drug delivery vehicles to provide targeted therapies against tumor cells. Targeting tumor microenvironments is another important application of anticancer materials, as it is a vital determinant of the final fate of cancer therapy. Moreover, effects of materials and their by-products on cancer stem cells are not well studied, so specific research should be conducted on this issue to reveal the molecular mechanisms involved.

This Special Issue has the ambition of providing a valuable collection of contributions and a platform for a scientific discussion focused on material-based strategies in the context of cancer therapy. Original research papers, short communications, and reviews are welcome in this Special Issue, the key topics of which include innovative treatment and synthesis/fabrication approaches, chemical and drug delivery systems, in vitro and in vivo experiments, as well as modelling and materials validation addressed to the broad field of cancer diagnosis and therapy.

Dr. Saeid Kargozar
Dr. Francesco Baino
Guest Editors

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