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New Materials for Biomedical Applications: Innovations from Collaborative Research

A Special Issue of Materials (ISSN 1996-1944) belonging to the section "Biomaterials".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 1347

Editor

Special Issue Information

Dear Colleagues,

In recent years, various new materials have emerged from diverse research fields, often arising from independent research and collaborative efforts. Collaborative research is not merely an “addition of knowledge”; it is a chemical reaction where new value emerges from the synthesis of different perspectives. In modern innovation, breaking through limitations with closed innovation alone is difficult, meaning that research conducted through industry–academia partnerships and inter-company collaborations is vitally important. This Special Issue invites submissions detailing recent innovations born from collaborative research. We anticipate that this Special Issue will serve as a catalyst for initiating new collaborative research endeavors.

Dr. Satoshi Komasa
Guest Editor

Manuscript Submission Information

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Keywords

  • innovation
  • collaborative research
  • biomaterials
  • in vitro
  • in vivo
  • new materials

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Published Papers (2 papers)

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Research

19 pages, 12611 KB  
Article
Physicochemical, Mechanical, and Histological Assessment of Explanted Polypropylene Meshes from Recurrent Abdominal Wall Hernia Repairs
by Olga A. Legonkova, Tatyana I. Vinokurova, Viktoria V. Stafford, Dmitriy I. Kopitsyn, Badri S. Gogia, Galina A. Davydova, Egor V. Kasatkin, Mariya I. Styazhkina, Rifat R. Alyautdinov, Vladimir A. Vinokurov, Victoria Yu. Grigorieva, Veronica Manescu (Paltanea), Iulian Vasile Antoniac and Julietta V. Rau
Materials 2026, 19(14), 3048; https://doi.org/10.3390/ma19143048 - 15 Jul 2026
Viewed by 428
Abstract
The purpose of this study is to investigate the physical, chemical, and structural characteristics of 13 polypropylene mesh endoprostheses explanted due to hernia recurrences across an in vivo timeline ranging from 1 to 14 years, as well as the morphology of the surrounding [...] Read more.
The purpose of this study is to investigate the physical, chemical, and structural characteristics of 13 polypropylene mesh endoprostheses explanted due to hernia recurrences across an in vivo timeline ranging from 1 to 14 years, as well as the morphology of the surrounding tissues, to assess the possible influence of polymer degradation on explantation timing. Physical and mechanical testing, gas chromatography–mass spectrometry, differential scanning calorimetry, infrared spectroscopy, and histological assessment of tissue response to the implanted endoprostheses were employed. The tensile strength and elongation measurements of the explanted meshes remained within functionally acceptable clinical ranges, showing no statistically significant decline compared to baseline parameters. Polypropylene monofilaments of mesh endoprostheses were subjected to surface changes in the form of transverse cracks during exposure to patient tissues; however, the depth of these cracks was self-limiting (confined to 3–7% of the filament diameter) and did not affect the bulk strength properties of the endoprostheses. Histological examination demonstrated a chronic foreign body response that transitioned from early focal necrosis to a stable tissue capsule. While these data suggest that superficial micro-cracking did not markedly compromise bulk mechanical performance over the 14-year span, localized physical or biological tissue–implant interactions could still contribute to structural instability, meaning polymer degradation cannot be definitively ruled out as a contributing factor to recurrence in all clinical cases. Full article
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18 pages, 3393 KB  
Article
Comparison of the Mechanical Properties and Surface Characteristics of Vat Photopolymerization Resin Materials and a Polymethyl Methacrylate Disc Material
by Fei Yu, Ryuhei Kanda, Yoshiya Hashimoto, Kazuhiko Suese, Koji Mitamura, Yasuyuki Kobayashi and Kosuke Kashiwagi
Materials 2026, 19(11), 2220; https://doi.org/10.3390/ma19112220 - 25 May 2026
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Abstract
Additive manufacturing using vat photopolymerization (VPP) resin materials has gained attention for fabricating dental prostheses; however, the effects of material type and build angle on their properties remain unclear. We compared the mechanical properties of two filler-containing VPP hybrid resins, SprintRay Ceramic Crown [...] Read more.
Additive manufacturing using vat photopolymerization (VPP) resin materials has gained attention for fabricating dental prostheses; however, the effects of material type and build angle on their properties remain unclear. We compared the mechanical properties of two filler-containing VPP hybrid resins, SprintRay Ceramic Crown (CC) and OnX Tough 2 (OT), with those of a conventional polymethyl methacrylate (PMMA) disc material, and evaluated the influence of build angle on surface characteristics, dimensional accuracy, and mechanical performance. Specimens were fabricated using a DLP system at build angles of 0°, 45°, and 90°. Vickers hardness, surface morphology and roughness, dimensional deviations, flexural strength, elastic modulus, and fracture energy were assessed according to relevant standards. CC exhibited significantly higher hardness and elastic modulus than PMMA and OT, whereas OT showed the highest fracture energy. Surface morphology and roughness were strongly affected by build angle, with 45° producing distinct periodic patterns and increased roughness. Dimensional evaluation revealed a tendency toward overbuilding, particularly in the vertical direction at 45°. Flexural properties were also influenced by build angle, with 45° generally providing favorable performance. Both material composition and build angle affect VPP-fabricated dental resin performance, highlighting the importance of appropriate material and processing selection for clinical applications. Full article
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