Ischemic Heart Disease in the Context of Different Comorbidities, Volume II

Dear Colleagues,

The field of cardiology is very dynamic, and is constantly evolving and improving. Our knowledge about myocardial ischemia is deepening every day, as major progress is made both in understanding its pathophysiological substrate and in improving diagnostic algorithms and therapeutic protocols.

Myocardial ischemia is the fundamental substrate of acute and chronic coronary syndromes. Beyond this major role, its importance resides in its coexistence with many pathological conditions in which myocardial ischemia appears either as an associated factor or as a consequence.

Firstly, the diagnosis of myocardial ischemia in the context of non-cardiac comorbidities can be a challenge for the clinician, who has the difficult task of choosing appropriate paraclinical investigations from many options—ECG, biomarkers, stress test, invasive and non-invasive imaging procedures—to establish a correct diagnosis.

Secondly, the high incidence and severe prognosis of myocardial ischemia highlight the need for continuous research in the field to optimize diagnosis and treatment, and to improve the prognosis and survival of patients.

Thirdly, atherosclerotic disease as a whole and myocardial ischemia in particular are frequently associated with a complex metabolic background. Innovative therapies bring important benefits, providing protection against atherosclerotic disease and significantly reducing major adverse cardiovascular events in dedicated clinical trials.

These are the main reasons why we chose this broad topic. Our goal is to form a team of specialists whose advanced experience allows us to understand the complex mechanisms of the bidirectional relationship between myocardial ischemia and various pathologies. Therefore, we invite you to share your knowledge and experience, and thus help to identify the best diagnostic and therapeutic solutions for our patients.

Dr. Irina-Iuliana Costache
Prof. Dr. Bogdan-Mircea Mihai
Dr. Minerva Codruta Badescu
Guest Editors

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