Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chronic Obstructive Pulmonary Disease (COPD): From Diagnosis and Comorbidities to Personalized Management and Palliative Care
edited by and Florin Mihaltan
submission deadline 10 Nov 2025 | 2 articles | Viewed by 16925 | Submission Open
Keywords: risk factors; systemic inflammation; phenotypes; cardio-pulmonary functional assessment; comorbidities; exacerbations; treatment; rehabilitation; prognosis tools; palliative care; management
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Chemotherapy and Hematopoietic Stem Cell Transplantation
edited by
submission deadline 15 Nov 2025 | Viewed by 154 | Submission Open
Keywords: hematopoietic stem cell transplantation; chemotherapy toxicity and conditioning regimens; graft-versus-host disease (GVHD) management; immunotherapy and cellular therapies
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Ehealth, Telemedicine, and AI in the Precision Medicine Era
edited by
submission deadline 20 Nov 2025 | 4 articles | Viewed by 20240 | Submission Open
Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Neurodegenerative Diseases: Molecular Pathology and Personalized Treatment submission deadline 20 Nov 2025 | 2 articles | Viewed by 9172 | Submission Open
Keywords: neurodegeneration; molecular pathology; precision medicine; biomarkers; personalized therapeutics
(This special issue belongs to the Section Mechanisms of Diseases)
Skin Pathophysiology and Management
edited by , Joanna Goldberg and Mahsa Babaei
submission deadline 20 Nov 2025 | 2 articles | Viewed by 8044 | Submission Open
Keywords: skin disease pathophysiology; skin disease diagnosis; skin disease treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Liquid Biopsy in Lung Cancer: Innovations in Precision Oncology submission deadline 20 Nov 2025 | Viewed by 299 | Submission Open
Keywords: liquid biopsy; lung cancer; biomarkers; diagnosis; personalized treatment
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Gynecological Endoscopy: From Personalized Diagnosis to Tailored Surgical Interventions
edited by , Dimitrios Zacharakis and
submission deadline 25 Nov 2025 | 2 articles | Viewed by 5508 | Submission Open
Keywords: gynecological endoscopy; minimally invasive and robotic surgeries; personalized gynecological care; gynecological healthcare; personalized diagnosis; genomic profiling; real-time imaging; AI algorithms; biomarker identification  
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Advances in Bariatric Surgery
edited by and Andrea Peri
submission deadline 25 Nov 2025 | 4 articles | Viewed by 4535 | Submission Open
Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Gynecology and Obstetrics submission deadline 25 Nov 2025 | 1 articles | Viewed by 2260 | Submission Open
Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Molecular Pathology in Cancer Research
edited by Maurizio Martini and Giuseppe Giuffré
submission deadline 25 Nov 2025 | 1 articles | Viewed by 1306 | Submission Open
Keywords: molecular pathology; diagnostic pathology; cancer diagnosis; biomarkers; targeted therapy; genomics
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Clinical Management and Personalized Treatment in Digestive Surgery submission deadline 25 Nov 2025 | Viewed by 418 | Submission Open
Keywords: digestive disease; digestive cancers; gastrointestinal surgery; stomach; pancreas; liver
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Medicine in Spine Surgery: Updates and Challenges
edited by Mark James Lambrechts
submission deadline 25 Nov 2025 | Viewed by 175 | Submission Open
Keywords: spine; orthopedic surgery; neurosurgery; precision; endoscopic spine; artificial disc replacement; spinal deformity; patient-specific alignment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Computer-Assisted Diagnosis and Personalized Treatment of Fracture
edited by Juan Jiménez-Delgado
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4902 | Submission Open
Keywords: fracture diagnosis; computer-assisted simulation; artificial intelligence in orthopedics; medical imaging advances; personalized fracture treatment; computational fracture analysis; surgical planning tools; virtual reality in orthopedics; forensic analysis of fractures; multiscale modeling of bone
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Advances and Innovations in Reconstructive and Plastic Surgery
edited by Laura Răducu
submission deadline 30 Nov 2025 | 3 articles | Viewed by 4254 | Submission Open
Keywords: plastic surgery; breast reconstruction; robotics; microsurgery; burns injury
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
New Insights into Personalized Medicine for Anesthesia and Pain
edited by and Guen Joo Choi
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4227 | Submission Open
Keywords: new insights; personalized medicine; anesthesia; pain management; perioperative analgesia; airway management; perioperative nausea; interventional pain care; critical care; minimally invasive surgery/robotic surgery; mechanical ventilation; chronic pain; acute pain; lumbar/cervical/thoracic/spinal pain; musculoskeletal pain
(This special issue belongs to the Section Personalized Medical Care)
Role of Genetic Tools in Diagnosis and Personalized Treatment for Neurological Diseases
edited by Federica Scalia
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2383 | Submission Open
Keywords: neurological disorders; molecular modeling; bioinformatics; genetic tools; genetic variants; omic technologies; DNA sequencing; newborn screening; therapeutic procedure; mechanism of action
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives
edited by Roberta Carbonara and
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2013 | Submission Open
Keywords: personalized radiotherapy; personalized oncology; adaptive radiotherapy; stereotactic radiotherapy; re-irradiation; immuno-radiotherapy; tumor microenvironment and radiotherapy
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine
edited by Jerome Rene Lechien
submission deadline 30 Nov 2025 | 3 articles | Viewed by 2001 | Submission Open
Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Epigenetics in Precision Medicine: From Mechanism to Therapy submission deadline 30 Nov 2025 | 1 articles | Viewed by 1819 | Submission Open
Keywords: epigenetics; precision medicine; methylation; histone modifications; non-coding RNA
(This special issue belongs to the Section Epigenetic Therapy)
Personalized Medicine in Gastrointestinal Surgical Oncology
edited by and Myoung-Won Son
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1489 | Submission Open
Keywords: personalized medicine; gastrointestinal surgical oncology; laparoscopic surgery; robotic surgery; AI in surgery; multimodal treatment; clinical trials; oncological outcomes
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers
edited by Gustavo Fabregat-Cid
submission deadline 30 Nov 2025 | Viewed by 216 | Submission Open
Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Obstetrics and Gynaecology
edited by
submission deadline 30 Nov 2025 | Viewed by 196 | Submission Open
Keywords: precision medicine; reproductive health; preeclampsia; gestational diabetes; ovarian cancer; targeted therapies; endometriosis
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Artificial Intelligence in Personalized Management of Cardiovascular Diseases submission deadline 30 Nov 2025 | Viewed by 189 | Submission Open
Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy; ethics; and governance
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Acute Myeloid Leukemia: Current Progress and Future Directions submission deadline 10 Dec 2025 | 1 articles | Viewed by 2212 | Submission Open
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Complications in Vascular Surgery: Current Updates and Perspectives
edited by
submission deadline 10 Dec 2025 | Viewed by 217 | Submission Open
Keywords: endoleak; visceral ischaemia; lower limb ischaemia; graft infection; aneurysm shrinkage; sac growing; transient ischemic attack; stroke; deep vein thrombosis; vascular injuries; embolization
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Oral Health: Innovative and Personalized Approaches
edited by , Heleni Vastardis and
submission deadline 15 Dec 2025 | 3 articles | Viewed by 4087 | Submission Open
Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Psychiatry: Challenges and Opportunities submission deadline 20 Dec 2025 | 9 articles | Viewed by 29153 | Submission Open
Keywords: psychiatry; personalized medicine; epidemiology; public health; addictions; schizophrenia; depression; mental health; precision psychiatry; treatment response; genetic factors; biomarkers; pharmacogenomics; behavioral interventions; comorbidity; substance abuse; neurobiology; psychiatric disorders; psychosocial factors; population health
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Advancements in Neurosurgical Oncology: Bridging Neurosurgery and Cancer Neuroscience submission deadline 20 Dec 2025 | 1 articles | Viewed by 11980 | Submission Open
Keywords: neuro-oncology; cancer progression; neural mechanisms in cancer; brain tumors; neurological implications of cancer; cancer-induced neuropathy; neural stem cells and cancer; neuroinflammation in cancer; neuroimaging in oncology; cancer therapeutics and neurological safety
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Plastic Surgery: New Perspectives and Innovative Techniques
edited by Joseph M. Escandón and
submission deadline 20 Dec 2025 | 4 articles | Viewed by 4364 | Submission Open
Keywords: plastic surgery procedures; free tissue flaps; gender-affirmation surgery; reconstructive procedures; lymphedema; breast cancer; oncologic reconstruction; body contouring; regenerative medicine; stem cell therapy; aesthetic surgery
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Integrating Mathematical Modeling and Data Analysis in Personalized Medical Research submission deadline 20 Dec 2025 | 2 articles | Viewed by 1930 | Submission Open
Keywords: personalized medicine; health informatics; mathematical modeling; data analysis; bioinformatics; artificial intelligence; machine learning
(This special issue belongs to the Section Omics/Informatics)
Personalized Medicine in Dental and Oral Health submission deadline 25 Dec 2025 | 4 articles | Viewed by 17511 | Submission Open
Keywords: oral health; systemic context; personalized medicine; pharmacogenomics; caries pathology; diagnostics; clinical evaluation; paraclinical evaluation
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Laparoscopy, Perioperative Care and Complications in Surgery for Gastrointestinal Diseases
edited by Michał Kisielewski
submission deadline 25 Dec 2025 | 2 articles | Viewed by 4159 | Submission Open
Keywords: laparoscopy; perioperative care; colorectal surgery; minimally invasive surgery; upper digestive surgery; hepatobiliary surgery; postoperative complications
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Artificial Intelligence and Computational Approaches for Clinical Pharmacology and Drug Development
edited by Paraskevi F. Katsakiori and
submission deadline 25 Dec 2025 | 1 articles | Viewed by 2288 | Submission Open
Keywords: personalized medicine; artificial intelligence; optimized therapies; computational models; drug development; clinical pharmacology; machine learning; radiopharmaceuticals; prediction models; digital healthcare
(This special issue belongs to the Section Pharmacogenetics)
Advancing Personalized Medicine: Targeting Oxidative Stress in Neurodegenerative Diseases
edited by Lucia Buccarello
submission deadline 25 Dec 2025 | 1 articles | Viewed by 1512 | Submission Open
Keywords: oxidative stress; neurodegeneration; biomarkers; neuroprotection; protein oxidation; neuroinflammation; protein degradation; personalized medicine; intracellular signaling; neuronal death
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Otolaryngology: New Challenges and Future Perspectives
edited by Jerome Rene Lechien
submission deadline 25 Dec 2025 | 1 articles | Viewed by 727 | Submission Open
Keywords: otolaryngology; oral cancer; oncology; head and neck surgery; minimally invasive; laryngology; artificial intelligence; rhinology; ENT; personalized
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Targeted Therapy and Biomarkers for Solid Tumors
edited by Anca Zgură and
submission deadline 25 Dec 2025 | Viewed by 385 | Submission Open
Keywords: targeted therapy; biomarkers; solid tumors; oncology; cancer immunology; oncology radiotherapy; personalized medicine; molecular targets; drug resistance; translational research
(This special issue belongs to the Section Mechanisms of Diseases)
Inflammatory Bowel Disease (IBD): Diagnosis and Personalized Treatment
edited by Abigail Raffner (formerly Basson)
submission deadline 25 Dec 2025 | Viewed by 271 | Submission Open
Keywords: inflammatory bowel disease; diagnostic tools; biomarkers; therapeutic strategies; molecular mechanisms; microbiome; genetic predispositions; environmental factors; personalized treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Diagnosis and Therapy in Renal Cell Carcinoma
edited by Antonio Nacchia
submission deadline 25 Dec 2025 | Viewed by 229 | Submission Open
Keywords: inflammation; kidney cancer; renal cell cancer; inflammatory markers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine and Management of Gynecologic Cancer
edited by Hooman Soleymani majd and
submission deadline 25 Dec 2025 | Viewed by 213 | Submission Open
Keywords: proteomic; genomic; biomarkers; precision medicine; molecular profiling; immunotherapy; gynecologic cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Plastic and Reconstructive Surgery: Challenges and Prospects
edited by Johnny Ionut Efanov and Alain Michel Danino
submission deadline 25 Dec 2025 | Viewed by 117 | Submission Open
Keywords: reconstructive surgery; plastic surgery; flaps reconstruction; breast reconstruction; 3D printing; personalized surgery; biomaterials; imaging-assisted surgery; robotics
(This special issue belongs to the Section Regenerative Medicine and Therapeutics)
Cancer Immunotherapy: Current Advancements and Future Perspectives submission deadline 31 Dec 2025 | 7 articles | Viewed by 17527 | Submission Open
Keywords: personalized immunotherapy; molecular pathways in cancer immunotherapy; precision medicine; molecular markers; molecular bases of abscopal effect; sustained therapeutic response
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Obstetrics and Gynecology and Women's Health—2nd Edition submission deadline 31 Dec 2025 | 2 articles | Viewed by 16219 | Submission Open
Keywords: uterine fibroids; uterine myoma; leiomyoma; uterine artery embolization; endometriosis; gynecological surgery; infertility; endocrinology; hysteroscopy; hormonal therapies; personalized medicine
(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)
Advancing Personalized Spine Surgery Through Minimally Invasive Techniques—Perspectives from Inter-American Society for Minimally Invasive Spine Surgery (SICCMI)
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 8865 | Submission Open
Keywords: spine surgery; minimally invasive techniques; personalized care; personalized medicine; precision imaging; 3D printing in orthopedics; biomarkers in spinal health; artificial intelligence in surgery; robotics in spine surgery; genomics and spinal disorders; pain management and rehabilitation; surgical navigation systems; biocompatible materials for implants; patient-specific surgical planning; regenerative medicine in spine health; future trends in spinal surgery
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Clinical and Experimental Surgery in Personalized Molecular Medicine
edited by and Manousos M. Konstadoulakis
submission deadline 31 Dec 2025 | 3 articles | Viewed by 7092 | Submission Open
Keywords: personalized molecular medicine; clinical practice; surgical research; surgical oncology; multidisciplinary approaches
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Recent Research on Personalized Approaches to Clinical Therapeutics and Medication Safety
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 4099 | Submission Open
Keywords: clinical therapeutics; medication safety; pharmacotherapy; personalized medicine; treatment optimization; polypharmacy
(This special issue belongs to the Section Epidemiology)
Biomarkers and Pathogenesis of Infectious Diseases: From Research to Personalized Medicine submission deadline 31 Dec 2025 | 2 articles | Viewed by 3393 | Submission Open
Keywords: biomarkers; infectious diseases; pathogenesis; personalized medicine
(This special issue belongs to the Section Disease Biomarkers)
Digital Pathology in Translational Medicine and Clinical Practice
edited by , and Filippo Fraggetta
submission deadline 31 Dec 2025 | 1 articles | Viewed by 3133 | Submission Open
Keywords: digital pathology; computational pathology; integrative pathology; computer-aided diagnosis; artificial intelligence; biomarker discovery
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Approaches in Spinal Deformity: Innovations in Diagnosis and Treatment submission deadline 31 Dec 2025 | 1 articles | Viewed by 922 | Submission Open
Keywords: adult spinal deformity; preoperative planning; minimally invasive spine surgery; sagittal malalignment; patient-specific hardware; precision medicine; personalized treatment
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Transfusion Medicine and Immunological Research
edited by Luca Mele
submission deadline 31 Dec 2025 | Viewed by 331 | Submission Open
Keywords: transfusion medicine; immunological responses; blood safety; cellular therapy; alloimmunity
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Platelet Disease submission deadline 31 Dec 2025 | Viewed by 213 | Submission Open
Keywords: personalized medicine; platelet-related pathologies; molecular biology; platelet dysfunction; molecular mechanisms; platelets
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