Atrial Fibrillation: Toward Personalized Medicine
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".
Deadline for manuscript submissions: 25 January 2026 | Viewed by 72
Special Issue Editor
2. Department of Experimental Medicine, University of Rome Tor Vergata, 00133 Rome, Italy
Interests: atrial fibrillation; heart failure; arrhythmia; sudden cardiac death; catheter ablation
Special Issue Information
Dear Colleagues,
Atrial fibrillation (AF) is a multifactorial condition characterized by marked heterogeneity in clinical presentation, risk profiles, and treatment responses. Recent advances in genetics have identified specific variants that predispose young individuals to AF, highlighting the importance of early detection and personalized therapeutic strategies. Simultaneously, the development of next-generation electroanatomical mapping systems is transforming our ability to define patient-specific atrial substrates, enabling more precise and effective ablation therapies. One of the most significant recent breakthroughs is the clinical introduction of pulsed field ablation—a non-thermal energy source that offers myocardial selectivity, reduced collateral damage, and enhanced procedural safety. With the increasing availability of genomic, imaging, and computational tools, the field is moving toward a more nuanced and individualized approach to rhythm management.
This Special Issue of the Journal of Personalized Medicine will explore the latest advancements in personalized strategies for AF, from genetic insights and technological innovations to their integration into clinical workflows. Contributions from both basic science and clinical practice are welcome to help shape the future of precision electrophysiology.
Dr. Vincenzo Mirco La Fazia
Guest Editor
Manuscript Submission Information
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Keywords
- atrial fibrillation
- personalized medicine
- genetic predisposition
- electroanatomical mapping
- pulsed field ablation
- genomics
- substrate characterization
- tailored ablation strategies
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