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Recent Advances in Oral Diseases—2nd Edition
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Recent Advances in Oral Diseases—2nd Edition

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Epidemiology".

Deadline for manuscript submissions: 30 January 2026 | Viewed by 1767

Special Issue Editor

Dr. Omar Kujan

E-Mail Website
Guest Editor
UWA Dental School, The University of Western Australia, 17 Monash Ave, Nedlands, WA 6009, Australia
Interests: oral cancer; oral potentially malignant disorders; biomarkers; oral diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Oral diseases are known for their wide prevalence globally, leading to a deterioration of general health if they are left unmanaged. Dental caries, periodontal disease, tooth loss, and cancers of the lips and oral cavity are the most prevalent oral diseases, contributing to a global burden. Personalised dentistry is a new avenue for the early diagnosis and effective treatment of oral diseases. Innovative avenues and platforms to either further the understanding of the pathobiology of oral diseases or effectively manage patients diagnosed with these conditions and lesions are of most need.

This Special Issue, therefore, focuses on the recent advances and developments of oral diseases from bench to bedside in order to improve the standard of care for patients with these conditions and lesions.

Dr. Omar Kujan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral diseases
  • dental care
  • periodontal diseases
  • tooth loss
  • oral cancers
  • personalised dentistry

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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12 pages, 984 KiB  
Article
Evaluating Telehealth Diagnostic Accuracy in Oral and Maxillofacial Diseases: A Comparative Study
by Jeremy Lau, Agnieszka M. Frydrych, Richard Parsons, Ramesh Balasubramaniam and Omar Kujan
J. Pers. Med. 2024, 14(12), 1147; https://doi.org/10.3390/jpm14121147 - 10 Dec 2024
Viewed by 943
Abstract
Objectives: This study evaluated the accuracy of diagnosing oral and maxillofacial diseases using telehealth. Methods: We recruited 100 patients from the Oral Health Centre of Western Australia. They were either new patients or existing patients with a condition not previously diagnosed. The patients [...] Read more.
Objectives: This study evaluated the accuracy of diagnosing oral and maxillofacial diseases using telehealth. Methods: We recruited 100 patients from the Oral Health Centre of Western Australia. They were either new patients or existing patients with a condition not previously diagnosed. The patients initially underwent a telehealth consultation without administrative or clinical staff assistance. On the same day, they also received a traditional in-office (face-to-face) consultation with an Oral Medicine registrar and/or consultant. Results: In this study, 70 patients were consulted via telehealth for a mucosal condition, while 30 were consulted for orofacial pain. When comparing telehealth diagnoses to in-person diagnoses, 65.7% of mucosal cases and 70% of orofacial pain cases had the same diagnosis. Furthermore, regarding the diagnoses within the chief complaint’s telehealth differential diagnosis list, 87.1% were similar in the mucosal cases, and 96.7% were similar in orofacial pain cases compared to the in-office consultation. Conclusions: Our study’s findings demonstrate that telehealth is less reliable than the gold standard in-person consultation for diagnosing oral diseases. However, it shows promise as an adjunctive service for screening, triaging, and monitoring patients. Further studies with guidelines for patients undergoing telehealth consultations to improve the diagnostic accuracy of oral and maxillofacial diseases are necessary. Full article
(This article belongs to the Special Issue Recent Advances in Oral Diseases—2nd Edition)
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Review

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18 pages, 1270 KiB  
Review
PD-L1/PD-1 Expression in the Treatment of Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders: An Overview of Reviews
by Huda Moutaz Asmael Al-Azzawi, Syed Ameer Hamza, Rita Paolini, Mathew Lim, Romeo Patini and Antonio Celentano
J. Pers. Med. 2025, 15(4), 126; https://doi.org/10.3390/jpm15040126 - 25 Mar 2025
Viewed by 387
Abstract
Objective: In this overview, we present compelling evidence from multiple systematic reviews and meta-analyses (SRMAs) and examine the prognostic role of the PD-L1/PD-1 axis, as well as the potential of personalized treatment strategies targeting this axis, in patients with oral squamous cell [...] Read more.
Objective: In this overview, we present compelling evidence from multiple systematic reviews and meta-analyses (SRMAs) and examine the prognostic role of the PD-L1/PD-1 axis, as well as the potential of personalized treatment strategies targeting this axis, in patients with oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs). Methods: Six databases were searched to retrieve systematic review and meta-analysis studies. The population of interest was patients with OSCC and OPMDs in whom the expression of PD-L1 and PD-1 had been investigated. At least one of the following outcomes was reported, along with at least one clinicopathological feature: overall survival, disease-free survival, or disease-specific survival. All studies were assessed for risk of bias using the AMSTAR 2 tool. Results: A total of 195 studies were found through the initial search, and after duplicate removal, 97 studies were screened by title and abstract. Finally, five systematic reviews and meta-analysis studies fit our inclusion criteria and were included in this review. Conclusions: Based on two published systematic reviews, our study revealed a lack of evidence for the prognostic value of PD-L1 in improving overall survival in oral cancer patients. However, it showed a correlation with specific clinicopathological features such as sex, lymph node metastasis, and HPV status. Full article
(This article belongs to the Special Issue Recent Advances in Oral Diseases—2nd Edition)
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