New Approaches in Pharmacogenomics

Dear Colleagues,

Inter-individual variability in drug responses is common and is likely to become increasingly problematic as the elderly population requiring multiple medications grows. The causes of this inter-individual variability mainly include genomic factors. Fortunately, analytical techniques have improved in recent years, so the need to incorporate pharmacogenomics into clinical practice is now recognized in many countries around the world. To reduce inter-individual variability in drug responses and increase drug efficacy and safety, we need to modify the drugs, the routes of administration, and the doses we use. However, despite this need, there is currently a huge knowledge gap in pharmacogenomics among healthcare practitioners, which poses the major dilemma of how incorporate pharmacogenomics into the healthcare system. Therefore, this Special Issue aims to collect efforts and findings on the application of currently developed or revealed pharmacogenomic knowledge and technologies to clinical practice in order to bridge this gap and overcome the dilemma.

Cutting-edge research in pharmacogenomics can create guidelines that can be personalized and applied to humans by verifying the results through prospective clinical trials, clinical cases, and functional genomics.

Suitable topics include drug- and disease-specific pharmacogenomic testing methods, user-friendly decision support tools/software for personalized medicine, collaborative data between genomic experts and healthcare providers, biomarkers for predicting treatment outcomes, innovative treatment approaches based on pharmacogenomics, innovative medical education programs/experiences, and research on integrating pharmacogenomics into clinical practice. In addition, authors are encouraged to submit novel findings on the biological function of genetic variants and their association with disease. Suitable papers include original research, reviews, and updated overviews of pharmacogenetics and pharmacogenomics.

Dr. Su-Jun Lee
Guest Editor

Manuscript Submission Information

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