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Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer Immunotherapy: Current Advancements and Future Perspectives

edited by

Stefano Forte

and

Gianluca Ferini

submission deadline 31 Dec 2025 | 8 articles | Viewed by 20707 | Submission Open

Keywords: personalized immunotherapy; molecular pathways in cancer immunotherapy; precision medicine; molecular markers; molecular bases of abscopal effect; sustained therapeutic response

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Obstetrics and Gynecology and Women's Health—2nd Edition

edited by

Panagiotis N. Tsikouras

submission deadline 31 Dec 2025 | 2 articles | Viewed by 19760 | Submission Open

Keywords: uterine fibroids; uterine myoma; leiomyoma; uterine artery embolization; endometriosis; gynecological surgery; infertility; endocrinology; hysteroscopy; hormonal therapies; personalized medicine

(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)

Clinical and Experimental Surgery in Personalized Molecular Medicine

edited by

Apostolos E. Papalois

and Manousos M. Konstadoulakis

submission deadline 31 Dec 2025 | 3 articles | Viewed by 8646 | Submission Open

Keywords: personalized molecular medicine; clinical practice; surgical research; surgical oncology; multidisciplinary approaches

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Biomarkers and Pathogenesis of Infectious Diseases: From Research to Personalized Medicine

edited by

César Henríquez-Camacho

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4093 | Submission Open

Keywords: biomarkers; infectious diseases; pathogenesis; personalized medicine

(This special issue belongs to the Section Disease Biomarkers)

Digital Pathology in Translational Medicine and Clinical Practice

edited by

Alessandro Caputo

Vincenzo L'Imperio

and Filippo Fraggetta

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3508 | Submission Open

Keywords: digital pathology; computational pathology; integrative pathology; computer-aided diagnosis; artificial intelligence; biomarker discovery

(This special issue belongs to the Section Mechanisms of Diseases)

Advances in Transfusion Medicine and Immunological Research

edited by Luca Mele

submission deadline 31 Dec 2025 | 1 articles | Viewed by 836 | Submission Open

Keywords: transfusion medicine; immunological responses; blood safety; cellular therapy; alloimmunity

(This special issue belongs to the Section Mechanisms of Diseases)

Innovative and Future Trends in Personalized Medicine for Retinal Diseases

edited by Joanna Dolar-Szczasny

submission deadline 31 Dec 2025 | 1 articles | Viewed by 504 | Submission Open

Keywords: retinal disease; age-related macular degeneration; diabetic retinopathy; gene therapy; retinal biomarker; personalized medicine; retinal imaging; molecular profile; artificial intelligence in ophthalmology; inherited retinal diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine and Surgery in Cardiovascular Disorders

edited by

Quynh Nguyen

and Edward D. Percy

submission deadline 31 Dec 2025 | Viewed by 246 | Submission Open

Keywords: precision medicine; cardiovascular disorders; cardiogenetics; translational medicine; genomic and multi-omics approaches to cardiovascular diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Platelet Disease

edited by

Tomas Jose Gonzalez-Lopez

submission deadline 31 Dec 2025 | Viewed by 245 | Submission Open

Keywords: personalized medicine; platelet-related pathologies; molecular biology; platelet dysfunction; molecular mechanisms; platelets

Personalized Treatments in Thoracic Oncology Surgery

edited by

Georg Schlachtenberger

and Alberto Lopez

submission deadline 10 Jan 2026 | 2 articles | Viewed by 2908 | Submission Open

Keywords: minimally invasive surgery; TNM classification; adjuvant treatment; long-term survival

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

From Acute Injury to Personalized Prevention—Developing Modern Strategies

edited by

Markus Gesslein

and

Eduard Kurz

submission deadline 10 Jan 2026 | Viewed by 233 | Submission Open

Keywords: orthopedics; acute injury; personalized prevention; innovative methodologies; musculoskeletal disorders; musculoskeletal injury; conservative therapy; functional testing; intervention

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Oxidative Stress and Antioxidant Therapy in Diseases

edited by

Evgenia Lymperaki

and

Ioannis Tsamesidis

submission deadline 15 Jan 2026 | 1 articles | Viewed by 3051 | Submission Open

Keywords: oxidative stress; antioxidants; ROS; diseases; antioxidants

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Medicine in Cardiovascular and Metabolic Diseases

edited by

Gaetano Santulli

submission deadline 15 Jan 2026 | Viewed by 267 | Submission Open

Keywords: cardiovascular disease; metabolic syndrome; precision health; telemedicine; biomarkers; pharmacogenomics; artificial intelligence; machine learning; epigenetics; diabetes

(This special issue belongs to the Section Mechanisms of Diseases)

New Perspectives, Challenges and Innovations in Modern Personalized Gynaecologic Oncology

edited by

Stamatios N. Petousis

submission deadline 20 Jan 2026 | 2 articles | Viewed by 16259 | Submission Open

Keywords: gynecologic oncology; surgical oncology; medical oncology; radiation oncology; diagnosis; ethics; palliative treatment

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Approaches in Pharmacogenomics

edited by

Su-Jun Lee

submission deadline 20 Jan 2026 | 5 articles | Viewed by 7896 | Submission Open

Keywords: personalized medicine; supporting tools/software for personalized medicine; pharmacogenomic test; pharmacogenomic education; drug response; genomic biomarker; functional genomics; healthcare system

(This special issue belongs to the Section Pharmacogenetics)

Clinical Research of Precision Neuro-Oncology

edited by

Giuseppe La Rocca

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2264 | Submission Open

Keywords: neuro-oncology; precision surgery; tailored treatment; innovation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Diagnosis, Treatment, and Survivorship of Lymphoma in the Era of Personalized Medicine

edited by Andrew Ip

submission deadline 20 Jan 2026 | Viewed by 236 | Submission Open

Keywords: lymphoma; non-Hodgkin lymphoma; Hodgkin lymphoma; personalized medicine; next-generation sequencing; early detection; survivorship

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

New Insights into Cardiac Electrophysiology and Personalized Medicine

edited by Ioanna Koniari

submission deadline 20 Jan 2026 | Viewed by 184 | Submission Open

Keywords: ablation; AF; PVI; PFA; ventricular arrhythmias; supraventricular arrhythmias; pacemakers; ICDs; CRT; conduction system pacing

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Medicine in Critical Care Medicine: Novel Challenges and Advances

edited by

Fernando Ramasco-Rueda

submission deadline 25 Jan 2026 | 2 articles | Viewed by 15639 | Submission Open

Keywords: critical care medicine; intensive care unit (icu); perioperative medicine; precision medicine; personalized therapy; hemodynamic monitoring; biomarkers; high-risk patients; organ support; artificial intelligence in critical care; sepsis; septic shock

(This special issue belongs to the Section Personalized Medical Care)

Dermatology: Diagnosis and Personalized Treatment

edited by Elisabeta Candrea and

Sorina Danescu

submission deadline 25 Jan 2026 | 1 articles | Viewed by 4214 | Submission Open

Keywords: biomarker; diagnostic tools; dermoscopy; ultrasound; confocal microscopy; therapeutic; personalized medicine

(This special issue belongs to the Section Mechanisms of Diseases)

Atrial Fibrillation: Toward Personalized Medicine

edited by

Vincenzo Mirco La Fazia

submission deadline 25 Jan 2026 | 1 articles | Viewed by 1886 | Submission Open

Keywords: atrial fibrillation; personalized medicine; genetic predisposition; electroanatomical mapping; pulsed field ablation; genomics; substrate characterization; tailored ablation strategies

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Therapy for Psychophysical Health: An Integrative Approach

edited by

Giada Pietrabissa

and

Giada Rapelli

submission deadline 25 Jan 2026 | 1 articles | Viewed by 1638 | Submission Open

Keywords: personalized therapy; patient-centered care; quality of life; psychosocial factors; adherence; self-management; multidisciplinary intervention; digital health tools

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Precision Medicine in Organ Transplantation: New Perspectives and Challenges

edited by

Tomasz Sta̧cel

submission deadline 25 Jan 2026 | Viewed by 437 | Submission Open

Keywords: organ transplantation; donor– recipient matching; immunosuppression strategies; transplant outcomes; diagnostics and perioperative care

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Dermatology

edited by

Liliana Gabriela Popa

and Calin Giurcaneanu

submission deadline 25 Jan 2026 | Viewed by 414 | Submission Open

Keywords: individualized treatment; dermatology; inflammatory skin diseases; bullous diseases; skin cancer; genodermatoses; chronic wounds

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Current Trends and Advances in Spondyloarthritis

edited by Francesca Bandinelli

submission deadline 30 Jan 2026 | 5 articles | Viewed by 27031 | Submission Open

Keywords: spondyloarthritis; ultrasound; MRI; HLA; gene; biomarkers; classification

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Recent Advances in Oral Diseases—2nd Edition

edited by

Omar Kujan

submission deadline 30 Jan 2026 | 2 articles | Viewed by 4948 | Submission Open

Keywords: oral diseases; dental care; periodontal diseases; tooth loss; oral cancers; personalised dentistry

(This special issue belongs to the Section Epidemiology)

Advances in Infectious Disease Epidemiology

edited by Cesar Henriquez-Camacho

submission deadline 31 Jan 2026 | 4 articles | Viewed by 5032 | Submission Open

Keywords: infectious diseases; epidemiology; genomics; machine learning; artificial intelligence; surveillance; vaccination; global health; stewardship programs

(This special issue belongs to the Section Epidemiology)

Sports Cardiology and Health Promotion Through Personalized Exercise Prescription

edited by

Luna Cavigli

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3403 | Submission Open

Keywords: sports cardiology; sports medicine; cardiomyopathies; personalized exercise prescription; cardiovascular prevention; cardiac rehabilitation; cardiopulmonary exercise test; cardiac imaging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Otolaryngology: Big Data Application in Personalized Medicine

edited by

Herng-Ching Lin

and Yen-Fu Cheng

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3116 | Submission Open

Keywords: otolaryngology; big data; epidemiology; precision medicine; personalized medicine; head and neck cancer

(This special issue belongs to the Section Omics/Informatics)

Musculoskeletal Diseases: Diagnosis, Rehabilitation and Personalized Treatment

edited by

Giacomo Farì

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3019 | Submission Open

Keywords: rehabilitation; regenerative medicine; telemedicine; musculoskeletal pain; sport; telemedicine; osteoarthritis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Precision Orthopedics: Evolving Shoulder, Hip, and Knee Surgery Through Intelligent Technology and Personalized Clinical Care

edited by Alessandra Berton

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2738 | Submission Open

Keywords: precision orthopedics; shoulder surgery; hip surgery; knee surgery; personalized medicine; artificial intelligence; robotic surgery; 3D printing; wearable sensors; patient outcomes

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Translational Research and Novel Therapeutics in Cutaneous Melanoma

edited by Maja Tolušić Levak and Martina Mihalj

submission deadline 31 Jan 2026 | Viewed by 425 | Submission Open

Keywords: cutaneus melanoma; immunopathology of melanoma; biomarkers; novel treatments; early diagnosis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Current Clinical Practice and Future Trends of Oral and Maxillofacial Surgery

edited by Rocco Franco

submission deadline 31 Jan 2026 | Viewed by 261 | Submission Open

Keywords: oral and maxillofacial surgery; digital technology; regenerative medicine; artificial intelligence; personalized treatment.

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Immunotherapy and Targeted Therapy in Gynecologic Cancer: Current Status and Challenges

edited by Brigida Anna Maiorano and

Mauro Francesco Pio Maiorano

submission deadline 31 Jan 2026 | Viewed by 251 | Submission Open

Keywords: immunotherapy; targeted therapy; gynecologic cancer; vulvar cancer; biomarkers; immune checkpoint inhibitors; HPV-related tumors; personalized oncology

(This special issue belongs to the Section Molecular Targeted Therapy)

Precision Medicine in Systemic Sclerosis and Idiopathic Inflammatory Myopathies

edited by

Silvia Bellando Randone

and Lorenzo Cavagna

submission deadline 31 Jan 2026 | Viewed by 243 | Submission Open

Keywords: systemic sclerosis; idiopathic inflammatory myopathies; precision medicine; autoimmune diseases; biomarkers; genetic

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Hematologic Malignancies: Advances and Prospects

edited by Khalil Saleh

submission deadline 31 Jan 2026 | Viewed by 126 | Submission Open

Keywords: CAR T-cells; bispecific antibodies; antibody– drug conjugates; bispecific T-cell engagers; artificial intelligence; mechanisms of resistance; biomarkers

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Complex and High-Risk Coronary Interventional Procedures

edited by

Zoltan Ruzsa

, Toth-Gayor Gabor and

Alexandru Achim

submission deadline 10 Feb 2026 | 2 articles | Viewed by 3396 | Submission Open

Keywords: complex high-risk intervention (CHIP); coronary bifurcation; coronary chronic total occlusion; severe coronary calcification; protected PCI; access site I during CHIP procedures

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Endometriosis

edited by Christine Bekos

submission deadline 10 Feb 2026 | Viewed by 762 | Submission Open

Keywords: microbiome; epigenetics; fatigue; laparoscopic surgery; lifestyle changes; endometriosis

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Diagnosis and Treatment of Digestive System Disorders

edited by Gengqing Song

submission deadline 10 Feb 2026 | 1 articles | Viewed by 531 | Submission Open

Keywords: personalized medicine; gastrointestinal disorders; precision diagnostics; functional GI disorders; gastrointestinal motility; microbiome; pharmacogenomics; gastrointestinal oncology

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Application of Genetic Diagnosis in Pediatrics

edited by Avinash Veerappa

submission deadline 10 Feb 2026 | Viewed by 158 | Submission Open

Keywords: pediatric diagnosis; rare diseases; genome sequencing; exome sequencing; genetic diseases; mutations

(This special issue belongs to the Section Omics/Informatics)

The Development of Echocardiography in Heart Disease

edited by Jolanta Justina Vaskelyte, Egle Rumbinaite and Vaida Mizariene

submission deadline 20 Feb 2026 | 6 articles | Viewed by 14145 | Submission Open

Keywords: echocardiography; speckle tracking; CAD; valvular pathology; myocardial/pericardial diseases; congenital defects; rare cardiac diseases; interventional procedures

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Clinical Diagnosis and Treatment in Otorhinolaryngology

edited by Delia Hînganu and Marius Valeriu Hînganu

submission deadline 20 Feb 2026 | 4 articles | Viewed by 5847 | Submission Open

Keywords: ENT surgery; multimodality imaging; prevention; voice formation; middle ear pathology; inner ear pathology

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Management and Treatment in Geriatrics

edited by

Carmen da Casa

and

Juan F. Blanco

submission deadline 20 Feb 2026 | Viewed by 225 | Submission Open

Keywords: geriatrics; personalized health care; artificial intelligence; comprehensive geriatric assessment; ageing; biomedical technology; health promotion; chronic disease management; rehabilitation; pharmacogenetics; neurodegenerative diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Retinal Diseases

edited by Henrik Faatz

submission deadline 25 Feb 2026 | 4 articles | Viewed by 6324 | Submission Open

Keywords: retinal disease; age-related macular degeneration; diabetic retinopathy; gene therapy; retinal biomarker; personalized medicine; retinal imaging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Ophthalmology: Diagnosis, Prevention, and Treatment

edited by Antonio Di Zazzo and

Takenori Inomata

submission deadline 25 Feb 2026 | 1 articles | Viewed by 6322 | Submission Open

Keywords: ocular surface; dry eye disease; scleral lenses; corneal disease; keratoconus

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

New Insights into Personalized Care in Advance Care Planning

edited by

Mitsunori Nishikawa

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4460 | Submission Open

Keywords: advance care planning; choices about future medical care; cultural differences; diversity; personalized care choices

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Depression and Anxiety: Recent Advances in Personalized Treatment and Management

edited by

Stefano Eleuteri

submission deadline 25 Feb 2026 | 1 articles | Viewed by 3020 | Submission Open

Keywords: personalized treatment; mood disorders and anxiety; treatment; therapy; depression and anxiety

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Novel Challenges and Advances in Pediatric Hematology and Hematologic Malignancies

edited by Katarzyna Pawińska-Wa̧sikowska

submission deadline 25 Feb 2026 | 1 articles | Viewed by 2989 | Submission Open

Keywords: pediatric hematology; hematology malignancies; therapies; diagnosis; immunotherapies; supportive care

(This special issue belongs to the Section Mechanisms of Diseases)

Advances in Precision Medicine of Oncology Radiotherapy

edited by

Giuseppe Iatí

and Silvana Parisi

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1015 | Submission Open

Keywords: novel radiotherapy approaches; novel drugs; novel diagnostic approaches; immunomodulation; omics; biomarkers; metabolic alterations; personalised medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Precision Medicine in Gastrointestinal Neoplasms

edited by Juan Torres-Melero and

María Jose Serrano

submission deadline 25 Feb 2026 | Viewed by 515 | Submission Open

Keywords: digestive cancers; molecular biology; gastrointestinal cancers; gynecological cancers

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

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