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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hematopoietic Stem Cell Transplantation: Current Research and New Perspectives

edited by

Lucia Prezioso

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1825 | Submission Open

Keywords: allogenic transplantation; autologous transplantation; infection; GVHD; transplant related mortality; transplant complications; conditioning regimen; donor lymphocyte infusion; minimal residual disease; graft versus leukemia

(This special issue belongs to the Section Hematology)

Electroencephalography: Advances in Clinical Applications

edited by

Leonardo S. Barbosa

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1785 | Submission Open

Keywords: electroencephalography; clinical EEG; machine learning; deep learning; seizure detection; sleep EEG; brain–computer interface; neurodegenerative disease; consciousness assessment; automated diagnosis; multimodal neu-roimaging; human-AI benchmarking

(This special issue belongs to the Section Clinical Neurology)

Cardiac MRI: Current Techniques and Future Directions

edited by

Édouard Gerbaud

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1704 | Submission Open

Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner

(This special issue belongs to the Section Cardiology)

Periodontal Diseases: Latest Advances in Diagnosis and Therapeutic Strategies

edited by Francesco Saverio Martelli and Giada Marroncini

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1683 | Submission Open

Keywords: periodontal diseases; precision dentistry; genetic susceptibility; oral microbiome; inflammatory biomarkers; personalized therapy; multidisciplinary approach; periodontal diagnostics; host response modulation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Thromboembolic Disease and Antithrombotic Therapy: 2nd Edition

edited by Prahlad Ho

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1646 | Submission Open

Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein throm-bosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Vir-chow’s triad; post thrombotic syndrome

(This special issue belongs to the Section Hematology)

Acute Management and Surgical Strategies in Orthopedic Trauma

edited by Hyung Keun Song

submission deadline 20 Nov 2026 | 3 articles | Viewed by 1596 | Submission Open

Keywords: orthopedic trauma; acute care; trauma surgery; damage control orthopedics; early definitive fixation; surgical timing; polytrauma; pelvic fracture; acetabular fracture; perioperative management; complications; clinical outcomes; trauma systems

(This special issue belongs to the Section Orthopedics)

Challenges in Emergency Medicine

edited by

Hugon Možina

and Gregor Prosen

submission deadline 20 Nov 2026 | 3 articles | Viewed by 1459 | Submission Open

Keywords: in-hospital and prehospital care; care of the critically ill; resuscitation and post-resuscitation management; point-of-care ultrasound; emergency surgical and procedural interventions; digitalization and emerging technolo-gies; emergency medicine

(This special issue belongs to the Section Emergency Medicine)

Digital Mental Health and Artificial Intelligence: Clinical Perspectives and Patient Safety

edited by

Stéphane Bouchard

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1390 | Submission Open

Keywords: mental health care; telepsychiatry; telepsychotherapy; patient safety; health care data; clinical practice; digital mental health interventions; artificial intelligence in psychiatry; digital trust human–robot interactions; social networks

(This special issue belongs to the Section Mental Health)

Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions

edited by Halina Cichoz-Lach and

Beata Kasztelan-Szczerbińska

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1211 | Submission Open

Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut–liver axis; organ-to-organ crosstalk

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Cardiac Arrhythmias

edited by

Giuseppina Maura Francese

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1144 | Submission Open

Keywords: clinical electrophysiology; inherited arrhythmia syndromes; arrhythmias in structural heart disease; catheter ablation; device-based therapy

(This special issue belongs to the Section Cardiology)

IBD Surgery and Short Bowel Syndrome

edited by

Federica Galiandro

and Paola Caprino

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1137 | Submission Open

Keywords: abdominal surgery; minimally invasive surgery; robotic surgery; complex abdominal surgery; intestinal failure; short bowel syndrome; perioperative management; surgical outcomes; multidisciplinary care; surgical treatment of inflammatory bowel disease (IBD)

(This special issue belongs to the Section General Surgery)

Clinical Diagnosis and Management of Neonatal Diseases—Second Edition

edited by

Arieh Riskin

and Ayala Gover

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1113 | Submission Open

Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring

(This special issue belongs to the Section Clinical Pediatrics)

Aiming for Early Detection and Prevention of Pulmonary Diseases

edited by

Nektarios Anagnostopoulos

and

Kostas A. Papavassiliou

submission deadline 20 Nov 2026 | 1 articles | Viewed by 1059 | Submission Open

Keywords: early diagnosis; prevention strategies; respiratory diseases; artificial intelligence; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; sleep-disordered breathing

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Drug Safety and Polypharmacy

edited by

Alfredo Vannacci

and

Giada Crescioli

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1055 | Submission Open

Keywords: polypharmacy; medication safety; adverse drug reactions; drug–drug interactions; pharmacovigilance; artificial intelligence in healthcare; precision medicine; deprescribing; pharmacoepidemiology

(This special issue belongs to the Section Pharmacology)

Advancing Mechanical Ventilation in Critical Care: From Clinical Foundations to Personalized Strategies

edited by

Edward A. Bittner

submission deadline 20 Nov 2026 | 2 articles | Viewed by 1045 | Submission Open

Keywords: mechanical ventilation; acute respiratory distress syndrome (ARDS); lung-protective ventilation; patient–ventilator interaction; personalized (precision) critical care

(This special issue belongs to the Section Intensive Care)

Advances in Thoracic Surgery: Minimally Invasive Techniques, Precision Lung Resection, and Emerging Technologies

edited by

Bassam Redwan

submission deadline 20 Nov 2026 | 1 articles | Viewed by 989 | Submission Open

Keywords: minimally invasive thoracic surgery; robotic-assisted thoracic surgery (RATS); video-assisted thoracic surgery (VATS); precision lung resection; lung cancer surgery; segmentectomy; 3D imaging and surgical planning; extra-corporeal lung support

(This special issue belongs to the Section General Surgery)

Towards an Improved Understanding of Alzheimer's and Related Dementias: Interdisciplinary and Clinical Progress

edited by

Juan Rodríguez-Mansilla

Blanca Gonzalez-Sanchez

and

María Jiménez-Palomares

submission deadline 20 Nov 2026 | 2 articles | Viewed by 988 | Submission Open

Keywords: Alzheimer’s disease; related dementias; neurodegeneration; biomarkers; neuroimaging; early diagnosis; cognitive decline; clinical management; therapeutic interventions; psychosocial care; risk factors; dementia prevention

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in HPV-Related Disease

edited by

Dominik Pruski

and

Sonja Millert-Kalińska

submission deadline 20 Nov 2026 | 1 articles | Viewed by 959 | Submission Open

Keywords: gynecological cancers; HPV; HPV vaccine; cervical cancer; precancerous lesions diagnostics

(This special issue belongs to the Section Obstetrics & Gynecology)

Challenges in the Diagnosis and Management of Chronic Respiratory Diseases

edited by

Aurelio Arnedillo

and

Alicia Padilla-Galo

submission deadline 20 Nov 2026 | 2 articles | Viewed by 904 | Submission Open

Keywords: chronic respiratory diseases; long-term respiratory care; comorbidities; COPD; asthma; interstitial lung disease; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Current Advances in Spinal Cord Stimulation Therapy

edited by Alessandro Dario

submission deadline 20 Nov 2026 | 2 articles | Viewed by 845 | Submission Open

Keywords: spinal cord stimulation; epidural stimulation; transcutaneous spinal cord stimulation; spasticity; neuropathic pain; Parkinson’s disease; paraplegia; Persistent Spinal Pain Syndrome Type 1; Persistent Spinal Pain Syndrome Type 2; diabetic polyneuropathy; electrical waveforms

(This special issue belongs to the Section Clinical Neurology)

Heart Valve Surgery: Challenges and Advances in Conventional Surgery and Transcatheter Valve Therapy

edited by

Francesco Nappi

submission deadline 20 Nov 2026 | 1 articles | Viewed by 842 | Submission Open

Keywords: mitral valve surgery; aortic valve surgery; tricuspid valve surgery; ross procedure; david procedure; transcatheter valve therapy; homograft valve replacement; infective endocarditis surgery

(This special issue belongs to the Section Cardiology)

Latest Advances and Prospects in Urogynecology and Pelvic Floor Surgery

edited by

Ewa Monika Barcz

submission deadline 20 Nov 2026 | 1 articles | Viewed by 836 | Submission Open

Keywords: urogynecology; pelvic floor disorders; pelvic organ prolapse; urinary incontinence; fecal incontinence; minimally invasive surgery; pelvic floor imaging; vaginal surgery; pelvic pain syndrome

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Updates on Oral Health and Dental Care

edited by Wojciech Niemczyk and Rafał Wiench

submission deadline 20 Nov 2026 | 1 articles | Viewed by 821 | Submission Open

Keywords: oral health management; dental care; oral inflammatory diseases; oral diseases; preventive dentistry; periodontitis; oral medicine; clinical dentistry; dental surgery; periodontology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Concepts in Diagnostic and Surgical HPB Technology

edited by

Spiros G. Delis

submission deadline 20 Nov 2026 | 1 articles | Viewed by 795 | Submission Open

Keywords: HPB surgery; minimal invasive approach; imaging; artificial intelligence; robotic surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Hypertrophic Cardiomyopathy: From the Researcher Bench to the Clinical Patient Bedside

edited by

Milorad Tesic

Vojislav Giga

and Dejana R. Popović

submission deadline 20 Nov 2026 | 1 articles | Viewed by 742 | Submission Open

Keywords: hypertrophic cardiomyopathy; advanced imaging techniques; echocardiographic; cardiac magnetic resonance; biomarkers; surgical and interventional procedures

(This special issue belongs to the Section Cardiology)

Obesity and the Airway: Disease Mechanisms, Associated Conditions, and Management

edited by

Mohamad R. Chaaban

submission deadline 20 Nov 2026 | 1 articles | Viewed by 737 | Submission Open

Keywords: obesity; airway; inflammation; rhinosinusitis; cerebrospinal fluid leak; asthma; chronic obstructive pulmonary disease; sleep; obstructive sleep apnea; intubation; laryngopharyngeal reflux; laryngotracheal stenosis

(This special issue belongs to the Section Respiratory Medicine)

Prostate Cancer: Clinical Advances and Prognosis Now and in the Near Future

edited by Josip Španjol

submission deadline 20 Nov 2026 | 1 articles | Viewed by 711 | Submission Open

Keywords: prostate cancer; immunotherapy; clinical trials; personalized medicine; artificial intelligence; robotic surgery; radical prostatectomy; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Psychological Safety: Bodily and Psychological Determinants in Clinical Settings

edited by

Andrea Poli

submission deadline 20 Nov 2026 | 1 articles | Viewed by 693 | Submission Open

Keywords: psychological safety; fear; psychological trauma; shame; dissociation; neuroception; trust; polyvagal theory

(This special issue belongs to the Section Mental Health)

Endocarditis: Clinical Updates on Diagnosis, Treatment and Management

edited by

Katarzyna Holcman

submission deadline 20 Nov 2026 | 1 articles | Viewed by 682 | Submission Open

Keywords: infective endocarditis; PET; SPECT; echocardiography; antimicrobial therapy; cardiac surgery; multimodality imaging

(This special issue belongs to the Section Cardiology)

Management Strategies for Traumatic Brain Injury in Neurocritical Care Unit

edited by Etrusca Brogi

submission deadline 20 Nov 2026 | 1 articles | Viewed by 675 | Submission Open

Keywords: traumatic brain injury; neurocritical care; intracranial pressure; cerebral perfusion; neuroprotection; TBI management; critical care strategies; outcome prediction; rehabilitation; monitoring

(This special issue belongs to the Section Clinical Neurology)

New Technological Treatments and Methods in Neurorehabilitation

edited by

József Tollár

submission deadline 20 Nov 2026 | 1 articles | Viewed by 605 | Submission Open

Keywords: neurorehabilitation; robotics; virtual reality; exoskeleton; humankinesiology physiotherapy; stroke; parkinson's disease; gait; physical rehabilitation; rehabilitation interventions

(This special issue belongs to the Section Clinical Neurology)

Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition

edited by

Elad Asher

submission deadline 20 Nov 2026 | 1 articles | Viewed by 581 | Submission Open

Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI

(This special issue belongs to the Section Cardiovascular Medicine)

Hip Fracture and Surgery: Clinical Updates and Challenges: 2nd Edition

edited by

Norio Imai

submission deadline 20 Nov 2026 | 1 articles | Viewed by 569 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Interventional Pulmonology: Advances and Future Directions—2nd Edition

edited by Martina Ferioli and Piero Candoli

submission deadline 20 Nov 2026 | 1 articles | Viewed by 561 | Submission Open

Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advancements in Radiology of Joint and Musculoskeletal Diseases

edited by

Gwendolyn Vuurberg

submission deadline 20 Nov 2026 | 1 articles | Viewed by 552 | Submission Open

Keywords: sports injuries; ligament injuries; ankle injury; prognostic imaging; individualized imaging; imaging algorithms; lower-extremity injury; clinical insights; knee injuries; groin and hip pain

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Updates in Kidney Cancer

edited by

Krzysztof Balawender

submission deadline 20 Nov 2026 | Viewed by 536 | Submission Open

Keywords: renal cell carcinoma (RCC); robot-assisted partial nephrectomy (RAPN); artificial intelligence in oncology; cryoablation; kidney cancer management

(This special issue belongs to the Section Nephrology & Urology)

Innovative Neurosurgery: Scientific Breakthroughs and Modern Practice

edited by Wolfgang Senker and Matthias Gmeiner

submission deadline 20 Nov 2026 | 1 articles | Viewed by 513 | Submission Open

Keywords: neurosurgery; innovative neurosurgery; clinical translational neuroscience; precision surgery; advanced neuroimaging; minimally invasive neurosurgery; robotic and endoscopic techniques; artificial intelligence in neurosurgery; spine and craniovertebral surgery; functional and vascular neurosurgery; surgical innovation and outcomes

(This special issue belongs to the Section Clinical Neurology)

Cardiomyopathy: Advances in Clinical Diagnosis and Treatment

edited by

Farbod Sedaghat-Hamedani

and Ali Amr

submission deadline 20 Nov 2026 | 1 articles | Viewed by 467 | Submission Open

Keywords: cardiomyopathy; precision medicine; heart failure; cardiac imaging; genetics; myocardial biopsy; arrhythmias; targeted therapy

(This special issue belongs to the Section Cardiology)

Resuscitation and Shock: Evolving Concepts and Clinical Strategies in Acute Care

edited by

Efstratios Karagiannidis

, Barbara P. Fyntanidou and

Aikaterini Apostolopoulou

submission deadline 20 Nov 2026 | 1 articles | Viewed by 433 | Submission Open

Keywords: resuscitation; shock; emergency medicine; critical care; hemodynamic monitoring; sepsis; trauma; vasopressors; fluid therapy; car-diopulmonary resuscitation (CPR); preclinical studies; cardiac arrest

(This special issue belongs to the Section Emergency Medicine)

Quality of Life in Patients with Gynecological Cancers

edited by

Katarzyna Plagens-Rotman

Piotr Merks

and Monika Englert-Golon

submission deadline 20 Nov 2026 | Viewed by 413 | Submission Open

Keywords: quality of life; gynecology oncology; ovarian cancer; breast cancer; cervical cancer; endometrial cancer; women; gynecological diseases; oncological diseases

(This special issue belongs to the Section Obstetrics & Gynecology)

The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease

edited by

Antonio Casado-Díaz

submission deadline 20 Nov 2026 | Viewed by 390 | Submission Open

Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy

(This special issue belongs to the Section Clinical Laboratory Medicine)

Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies

edited by Carla Contaldi

submission deadline 20 Nov 2026 | Viewed by 368 | Submission Open

Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification

(This special issue belongs to the Section Cardiology)

Myocardial Infarction: The Latest Advances and Prospects

edited by

Stylianos Daios

and Antonios Ziakas

submission deadline 20 Nov 2026 | Viewed by 349 | Submission Open

Keywords: coronary artery disease; myocardial infarction; PPCI; echocardiography; antiplatelet agents; radial access; global longitudinal strain

(This special issue belongs to the Section Cardiology)

Recent Advances in Hip and Knee Arthroplasty: Clinical Trends

edited by

Dragos Apostu

submission deadline 20 Nov 2026 | Viewed by 327 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; total joint replacement; osteoarthritis; surgical techniques; implant innovation; revision strategies; complication prevention; revision strategies

(This special issue belongs to the Section Orthopedics)

Integrated Management of Cardiorenal Metabolic Syndrome: From Obesity to Chronic Kidney Disease

edited by

Juan José Gorgojo-Martínez

submission deadline 20 Nov 2026 | Viewed by 304 | Submission Open

Keywords: cardiorenal metabolic syndrome; adipose tissue dysfunction; Insulin resistance; ectopic adiposity; cardiometabolic therapies

(This special issue belongs to the Section Endocrinology & Metabolism)

Advanced Technologies in Thoracic Anesthesia

edited by

Izumi Kawagoe

and

Hyun-joo Ahn

submission deadline 20 Nov 2026 | Viewed by 296 | Submission Open

Keywords: thoracic anesthesia; thoracic analgesia; preoperative management; enhanced recovery after surgery; thoracic Block; video-assisted thoracic surgery; robotic-assisted thoracic surgery; post-thoracotomy syndrome; airway device

(This special issue belongs to the Section Anesthesiology)

Recent Advances in the Diagnosis and Treatment of Breast Cancer

edited by

Alessandro Fancellu

submission deadline 20 Nov 2026 | Viewed by 291 | Submission Open

Keywords: breast cancer screening; diagnosis; surgery; radiotherapy; targeted treatment; neoadjuvant; quality of life

(This special issue belongs to the Section Oncology)

Advances and Challenges in the Diagnosis and Treatment of Epilepsy

edited by

Elena Pasini

submission deadline 20 Nov 2026 | Viewed by 273 | Submission Open

Keywords: epilepsy; diagnosis; treatment; epilepsy surgery; clinical management

(This special issue belongs to the Section Clinical Neurology)

Advances in the Management of Cancer Pain

edited by Wojciech Leppert

submission deadline 20 Nov 2026 | Viewed by 272 | Submission Open

Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management

(This special issue belongs to the Section Epidemiology & Public Health)

Colorectal Surgery: New Insights and Emerging Trends

edited by Marisa D. Santos, Nuno José Gomes Rama and Manuel Limbert

submission deadline 20 Nov 2026 | Viewed by 269 | Submission Open

Keywords: colorectal surgery; minimally invasive colorectal surgery; colorectal laparoscopic surgery; robotic-assisted colorectal surgery; precision colorectal surgery; enhanced recovery after surgery (ERAS); colorectal cancer; sphincter-preserving procedures; transanal surgery; pelvic floor surgery; personalized medicine; molecular profiling; biomarkers; artificial intelligence; image-guided surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 501-550 on page 11 of 30.

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