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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Quality of Life in Patients with Gynecological Cancers

edited by

Katarzyna Plagens-Rotman

Piotr Merks

and Monika Englert-Golon

submission deadline 20 Nov 2026 | Viewed by 426 | Submission Open

Keywords: quality of life; gynecology oncology; ovarian cancer; breast cancer; cervical cancer; endometrial cancer; women; gynecological diseases; oncological diseases

(This special issue belongs to the Section Obstetrics & Gynecology)

The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease

edited by

Antonio Casado-Díaz

submission deadline 20 Nov 2026 | Viewed by 395 | Submission Open

Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy

(This special issue belongs to the Section Clinical Laboratory Medicine)

Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies

edited by Carla Contaldi

submission deadline 20 Nov 2026 | Viewed by 384 | Submission Open

Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification

(This special issue belongs to the Section Cardiology)

Myocardial Infarction: The Latest Advances and Prospects

edited by

Stylianos Daios

and Antonios Ziakas

submission deadline 20 Nov 2026 | Viewed by 357 | Submission Open

Keywords: coronary artery disease; myocardial infarction; PPCI; echocardiography; antiplatelet agents; radial access; global longitudinal strain

(This special issue belongs to the Section Cardiology)

Recent Advances in Hip and Knee Arthroplasty: Clinical Trends

edited by

Dragos Apostu

submission deadline 20 Nov 2026 | Viewed by 346 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; total joint replacement; osteoarthritis; surgical techniques; implant innovation; revision strategies; complication prevention; revision strategies

(This special issue belongs to the Section Orthopedics)

Advanced Technologies in Thoracic Anesthesia

edited by

Izumi Kawagoe

and

Hyun-joo Ahn

submission deadline 20 Nov 2026 | Viewed by 317 | Submission Open

Keywords: thoracic anesthesia; thoracic analgesia; preoperative management; enhanced recovery after surgery; thoracic Block; video-assisted thoracic surgery; robotic-assisted thoracic surgery; post-thoracotomy syndrome; airway device

(This special issue belongs to the Section Anesthesiology)

Recent Advances in the Diagnosis and Treatment of Breast Cancer

edited by

Alessandro Fancellu

submission deadline 20 Nov 2026 | Viewed by 310 | Submission Open

Keywords: breast cancer screening; diagnosis; surgery; radiotherapy; targeted treatment; neoadjuvant; quality of life

(This special issue belongs to the Section Oncology)

Hepato-Pancreato-Biliary (HPB) Surgery: Precision and Outcomes

edited by Florian W. R. Vondran, Felix Oldhafer and Celia Villodre

submission deadline 20 Nov 2026 | Viewed by 294 | Submission Open

Keywords: hepato-pancreato-biliary surgery; liver surgery; minimally invasive surgery; robotic surgery; multidisciplinary treatment

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances and Challenges in the Diagnosis and Treatment of Epilepsy

edited by

Elena Pasini

submission deadline 20 Nov 2026 | Viewed by 291 | Submission Open

Keywords: epilepsy; diagnosis; treatment; epilepsy surgery; clinical management

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Psychotic Disorders: Precision Diagnosis and Personalized Treatment

edited by

Ana Barajas

submission deadline 20 Nov 2026 | Viewed by 284 | Submission Open

Keywords: psychotic disorders; early detection; precision diagnosis; personalized interventions; functional recovery; personal recovery; cognitive remediation; psychosocial treatment; recovery-oriented care; individualized care plans; digital mental health; telepsychiatry; artificial intelligence; virtual reality; predictive modeling

(This special issue belongs to the Section Mental Health)

Advances in the Management of Cancer Pain

edited by Wojciech Leppert

submission deadline 20 Nov 2026 | Viewed by 283 | Submission Open

Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management

(This special issue belongs to the Section Epidemiology & Public Health)

Colorectal Surgery: New Insights and Emerging Trends

edited by Marisa D. Santos, Nuno José Gomes Rama and Manuel Limbert

submission deadline 20 Nov 2026 | Viewed by 281 | Submission Open

Keywords: colorectal surgery; minimally invasive colorectal surgery; colorectal laparoscopic surgery; robotic-assisted colorectal surgery; precision colorectal surgery; enhanced recovery after surgery (ERAS); colorectal cancer; sphincter-preserving procedures; transanal surgery; pelvic floor surgery; personalized medicine; molecular profiling; biomarkers; artificial intelligence; image-guided surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Fertility and Reproductive Health in Women

edited by

Stylianos Vagios

submission deadline 20 Nov 2026 | Viewed by 272 | Submission Open

Keywords: female fertility; reproductive health; infertility; assisted reproductive technology; reproductive endocrinology; ovarian reserve; reproductive aging; PCOS; endometriosis; fertility preservation

(This special issue belongs to the Section Obstetrics & Gynecology)

Robotic Surgery in Urology: Current Updates and Innovations

edited by Scott Leslie

submission deadline 20 Nov 2026 | Viewed by 261 | Submission Open

Keywords: robotics; oncology; prostatectomy; nephrectomy; bladder; transplant; minimally-invasive; nephroureterectomy; reconstructive; pyeloplasty; novel; laparoscopic

(This special issue belongs to the Section Nephrology & Urology)

Advances in Adult Congenital Heart Disease: From Diagnosis to Long-Term Management

edited by Michael Huntgeburth

submission deadline 20 Nov 2026 | Viewed by 253 | Submission Open

Keywords: adult congenital heart disease; ACHD; long-term management; lifetime management; complications; arrhythmia; heart failure; endocarditis; pulmonary arterial hypertension; comorbidities; interventional treatment; surgical treatment; rehabilitation

(This special issue belongs to the Section Cardiology)

Echocardiography: Clinical Updates and Perspectives

edited by Isabella Leo and Giulia La Vecchia

submission deadline 20 Nov 2026 | Viewed by 247 | Submission Open

Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; speckle-tracking echocardiog-raphy; myocardial strain imaging; contrast echocardiography; transesophageal echocardiography; valvular heart disease; structural heart disease; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Innovations in Minimally Invasive and Personalized Urogynecology

edited by Günter Karl Noé and

Anna Pitsillidi

submission deadline 20 Nov 2026 | Viewed by 244 | Submission Open

Keywords: urogynecology; pelvic floor disorders; minimally invasive reconstructive techniques; personalized and regenerative treatment strategies

(This special issue belongs to the Section Obstetrics & Gynecology)

Application of Magnetic Resonance Imaging in Cardiovascular Disease

edited by Dhrubajyoti Bandyopadhyay, Aneesh S. Dhorepatil and

Vivek Amit Modi

submission deadline 20 Nov 2026 | Viewed by 242 | Submission Open

Keywords: cardiac MRI; tricuspid regurgitation; parametric imaging; 4D flow; WIP; flow reserve; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

New Challenges in Maternal–Fetal Medicine: 2nd Edition

edited by

Marzena Laskowska

submission deadline 20 Nov 2026 | Viewed by 238 | Submission Open

Keywords: thrombocytopenia in pregnancy; multiple pregnancies; placental abruption; DIC; sepsis; chorioamnionitis; cholestasis; postpartum hemorrhage; emergency cervical cerclage; problems in pregnancy and labor; pregnancy complications; spina bifida; fetal well-being evaluation

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Concepts of Cardio–Renal Interactions

edited by

Yacov Shacham

submission deadline 20 Nov 2026 | Viewed by 238 | Submission Open

Keywords: AKI; cardiorenal syndrome; contrast; biomarkers; renal insufficiency; cardio-nephrology; organ crosstalk

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Insights into Hearing Disorders: Towards Precision Diagnosis to Improve Outcomes and Quality of Life

edited by

Tiziana Di Cesare

submission deadline 20 Nov 2026 | Viewed by 227 | Submission Open

Keywords: hearing loss; hearing disorders; hearing aids; cochlear implant; hearing outcomes; auditory rehabilitation; quality of life

(This special issue belongs to the Section Otolaryngology)

From the Silk Road of Endoscopy to the Roads to Rome V of Neurogastroenterology: Dual Pathways Shaping Modern Gastroenterology

edited by Stefano Kayali

submission deadline 20 Nov 2026 | Viewed by 223 | Submission Open

Keywords: endoscopy; advanced imaging; minimally invasive therapies; gastrointestinal diagnostics; gut–brain interaction; DGBI; Rome V; neurogastroenterology; clinical innovation; GI physiology

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Optimizing Catheter Ablation for Atrial Fibrillation: Emerging Technologies and Clinical Progress

edited by Naiara Calvo

submission deadline 20 Nov 2026 | Viewed by 221 | Submission Open

Keywords: atrial fibrillation; pulsed field ablation; electroanatomical mapping; catheter ablation; electroporation; pulmonary veins

(This special issue belongs to the Section Cardiology)

Practical Use of Technologies in Neuro–Oncological Surgery Across Different Settings

edited by Davide Milani

submission deadline 20 Nov 2026 | Viewed by 217 | Submission Open

Keywords: neuro-oncology; surgical technology; neuronavigation; intraoperative ultrasound; fluorescence-guided surgery; augmented reality; artificial intelligence; surgical innovation; clinical practice

(This special issue belongs to the Section Clinical Neurology)

Paediatric Thyroid Cancer: Diagnosis and Therapeutic Strategies

edited by Paul Z. Benitez-Aguirre,

Andrew J. Bauer

, Antoinette Anazodo and Theodore W. Laetsch

submission deadline 20 Nov 2026 | Viewed by 203 | Submission Open

Keywords: paediatric thyroid cancer; differentiated thyroid carcinoma; molecular diagnostics; gene fusions (RET, NTRK, BRAF); targeted therapy; neoadjuvant therapy; adjuvant therapy; radioactive iodine (131I); dosimetry; tumour response and shrinkage; multidisciplinary models of care; survivorship and late effects

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Advances in Immune-Mediated Inflammatory Diseases

edited by

Lovro Lamot

submission deadline 20 Nov 2026 | 1 articles | Viewed by 181 | Submission Open

Keywords: pediatric immune-mediated inflammatory diseases (IMIDs); juvenile idiopathic arthritis; systemic lupus erythematosus; pediatric vasculitis; IgA nephropathy; complement-mediated kidney diseases; inflammatory bowel diseases; organ-specific inflammation; biomarkers for disease activity and diagnosis; biologic and targeted therapies; early recognition and diagnostic strategies; multidisciplinary care and integrated management

(This special issue belongs to the Section Immunology & Rheumatology)

Sexually Transmitted Infections: Persistent Challenges and Innovative Solutions

edited by Thomas E. Dobbs and

Mauda L. Monger

submission deadline 20 Nov 2026 | Viewed by 171 | Submission Open

Keywords: sexually transmitted infections (STIs); sexual and reproductive health; STI prevention and control; public health interventions; prevention advancements in sexual health; stigma and sexual health

(This special issue belongs to the Section Infectious Diseases)

Advances in Fetal Medicine: AI Integration and Advancements

edited by Christos Anthoulakis

submission deadline 20 Nov 2026 | Viewed by 167 | Submission Open

Keywords: fetal medicine; artificial intelligence; obstetrical complications; fetal syndromes; genetic conditions

(This special issue belongs to the Section Obstetrics & Gynecology)

Interventional Pain Management: Current Evidence and Innovative Advances

edited by Jamal Hasoon

submission deadline 24 Nov 2026 | 3 articles | Viewed by 4846 | Submission Open

Keywords: interventional pain management; chronic pain; image-guided procedures; injection techniques; neuromodulation; peripheral nerve blocks; radiofrequency ablation; minimally invasive spine interventions; artificial intelligence in medicine; quality improvement; clinical outcomes

(This special issue belongs to the Section Anesthesiology)

The Management of Chronic Cholestatic Diseases

edited by

Maria Consiglia Bragazzi

submission deadline 24 Nov 2026 | Viewed by 293 | Submission Open

Keywords: chronic cholestatic liver diseases; cholestasis; primary biliary cholangitis; primary sclerosing cholangitis; cholangiocar-cinoma

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Ventilation in Critical Care Medicine: 2nd Edition

edited by Gianluca Zani

submission deadline 25 Nov 2026 | 5 articles | Viewed by 35202 | Submission Open

Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation

(This special issue belongs to the Section Intensive Care)

Advances in the Diagnosis and Treatment of Glaucoma

edited by

Alessio Martucci

submission deadline 25 Nov 2026 | 13 articles | Viewed by 21770 | Submission Open

Keywords: OCT; glaucoma; MIGS; neuroprotection; drug delivery systems; artificial intelligence; pharmacologic agents; per-sonalized medicine

(This special issue belongs to the Section Ophthalmology)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 Nov 2026 | 4 articles | Viewed by 5509 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 Nov 2026 | 3 articles | Viewed by 5283 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Physical Activity, Exercise and Health: Implications for Clinical Practice

edited by

Nuria Marín-Jiménez

submission deadline 25 Nov 2026 | 3 articles | Viewed by 4666 | Submission Open

Keywords: physical activity; exercise prescription; clinical practice; chronic disease management; rehabilitation; preventive medicine; personalized medicine; sex and gender differences

(This special issue belongs to the Section Sports Medicine)

Clinical Advances in Gastrointestinal Endoscopy

edited by

Ivan Žaja

and Željko Puljiz

submission deadline 25 Nov 2026 | 4 articles | Viewed by 4591 | Submission Open

Keywords: endoscopy; polyps; EMR; ESD; POEM; balloon dilatation; coagulation; imaging; AI imaging

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 Nov 2026 | 3 articles | Viewed by 3650 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Hematological Neoplasms: Diagnosis, Treatment, and Management in the Department of Veterans Affairs

edited by Solomon A. Graf, Daphne R. Friedman and Suman Kambhampati

submission deadline 25 Nov 2026 | 4 articles | Viewed by 3140 | Submission Open

Keywords: hematologic malignancies; veterans affairs; therapeutics; biomarkers; rural medicine; integrated healthcare; demographics; exposures; trials in progress; treatment pathways

(This special issue belongs to the Section Hematology)

Clinical Advances in Personalized Psychiatry

edited by

Rosaria Di Lorenzo

submission deadline 25 Nov 2026 | 4 articles | Viewed by 3081 | Submission Open

Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments

(This special issue belongs to the Section Mental Health)

Epilepsy and Cerebrovascular Disorders

edited by

Leonardo Roever

submission deadline 25 Nov 2026 | 2 articles | Viewed by 2903 | Submission Open

Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience

(This special issue belongs to the Section Clinical Neurology)

Advances in the Clinical Management of Diabetic Retinopathy

edited by

Takeshi Iwase

submission deadline 25 Nov 2026 | 4 articles | Viewed by 2490 | Submission Open

Keywords: retinal imaging; clinical outcomes; optical coherence tomography (OCT); vitrectomy; blood flow

(This special issue belongs to the Section Ophthalmology)

Recent Advances in Minimally Invasive Surgery and Endoscopy of Gynecologic Oncology

edited by Hiroaki Komatsu,

Eiji Kondo

and

Tsukasa Baba

submission deadline 25 Nov 2026 | 3 articles | Viewed by 2403 | Submission Open

Keywords: cervical cancer; ovarian cancer; gynecologic cancer; robotic surgery; minimally invasive surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Novel Approaches and Techniques in Neurosurgery

edited by

Ismail Zaed

and

Mario Ganau

submission deadline 25 Nov 2026 | 4 articles | Viewed by 2171 | Submission Open

Keywords: neurosurgery; minimally invasive neurosurgery; endoscopic neurosurgery; spine surgery; surgical robotics; neu-ro-navigation; intraoperative imaging; artificial intelligence; neuro-oncology surgery; skull base surgery; im-age-guided surgery

(This special issue belongs to the Section Clinical Neurology)

The Current Concept and Emerging Treatments of Coronary Artery Disease (CAD)

edited by Simone Fezzi and Roberto Scarsini

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1959 | Submission Open

Keywords: coronary physiology; intracoronary imaging; imaging-derived computational physiology; drug-coated balloon and bioresorbable scaffolds; virtual PCI; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Kidney Transplantation: 2nd Edition

edited by Pedro Ruiz-Esteban, Domingo Hernández-Marrero and Verónica López-Jiménez

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1778 | Submission Open

Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition

edited by

Luca Bertoglio

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1344 | Submission Open

Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies

(This special issue belongs to the Section Vascular Medicine)

Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery

edited by Pari Naz Mohanna and Ayush Kapila

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1343 | Submission Open

Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Latest Clinical Advances in Refractive Surgery

edited by

Francesco D'Oria

and Giovanni Alessio

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1179 | Submission Open

Keywords: refractive surgery; corneal surgery; complications; innovative surgical techniques; diagnostic technologies

(This special issue belongs to the Section Ophthalmology)

Clinical Advances in Management of Urologic Diseases

edited by Francesco Pio Bizzarri and Calogero Casà

submission deadline 25 Nov 2026 | 1 articles | Viewed by 1062 | Submission Open

Keywords: prostate cancer; bladder cancer; kidney cancer; uro-oncology; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management of Female Pelvic Floor Disorders

edited by

Andrea Braga

and Stefano Salvatore

submission deadline 25 Nov 2026 | 1 articles | Viewed by 1002 | Submission Open

Keywords: urinary incontinence; pelvic organ prolapse; pelvic floor disorders; pelvic reconstructive surgery; anal incontinence

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 351-400 on page 8 of 30.

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