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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ocular Surface Disease: Epidemiology, Diagnosis and Management

edited by

Sandeep K. Dhallu

and

Nicole Carnt

submission deadline 20 Feb 2027 | 3 articles | Viewed by 4632 | Submission Open

Keywords: dry eye disease; risk factors; ocular surface disease; inflammatory biomarkers; anterior segment imaging; emerging therapies

(This special issue belongs to the Section Ophthalmology)

Clinical Advances in the Pharmacotherapy of Diabetes

edited by Jonathan Watanabe,

Joshua J. Neumiller

and

Cheyenne Frazier

submission deadline 20 Feb 2027 | 3 articles | Viewed by 4533 | Submission Open

Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies

(This special issue belongs to the Section Pharmacology)

Advances in Hepatitis: Prevention, Treatment, and Global Health Impact

edited by

Michał Brzdęk

Dorota Zarębska-Michaluk

and

Krystyna Dobrowolska

submission deadline 20 Feb 2027 | 4 articles | Viewed by 4504 | Submission Open

Keywords: hepatitis B; hepatitis C; liver disease; direct-acting antivirals (DAAs); global health; public health policy; viral hepa-titis elimination; health disparities; cirrhosis; vaccination programs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Feb 2027 | 4 articles | Viewed by 4454 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Clinical Management of Traumatic Brain Injury

edited by Adam James Wells and Peter Hutchinson

submission deadline 20 Feb 2027 | 4 articles | Viewed by 3987 | Submission Open

Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence

(This special issue belongs to the Section Clinical Neurology)

Stroke Care: From Acute Interventions to Long-Term Recovery

edited by

Aikaterini Theodorou

and

Georgios Tsivgoulis

submission deadline 20 Feb 2027 | 2 articles | Viewed by 3954 | Submission Open

Keywords: cerebrovascular diseases; acute ischemic stroke; intravenous thrombolysis; endovascular thrombectomy; intracerebral hemorrhage; etiology; cerebral amyloid angiopathy; stroke rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Advanced Endoscopy and Imaging in Gastrointestinal Diseases

edited by

Iancu Dana Monica

and

Paul-Andrei Ștefan

submission deadline 20 Feb 2027 | 5 articles | Viewed by 3807 | Submission Open

Keywords: advanced endoscopy; gastrointestinal imaging; minimally invasive therapy; early diagnosis; image-guided intervention; surgical planning; patient outcomes; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Research on Minimally Invasive Spine Surgery

edited by Daniel Fahim

submission deadline 20 Feb 2027 | 7 articles | Viewed by 3788 | Submission Open

Keywords: minimally invasive spine surgery; spine tumors; spine trauma; spine fractures; lumbar stenosis; lumbar spondylolisthesis; lumbar disc herniation; lumbar radiculopathy; thoracic disc herniations; cervical radiculopathy

(This special issue belongs to the Section Orthopedics)

Cardiotoxicity Within Cardio-Oncology: Clinical Advances from Prediction to Management

edited by

Massimiliano Camilli

submission deadline 20 Feb 2027 | 4 articles | Viewed by 3562 | Submission Open

Keywords: cardio-oncology; cardiotoxicity; cancer therapy–related cardiac dysfunction; heart failure in cancer patients; biomarkers; multimodality imaging; risk stratification; cardioprotection; cancer survivors' care; multidisciplinary approach

(This special issue belongs to the Section Cardiology)

Clinical Management of Patients Before and After Kidney Transplantation

edited by

Izabela Zakrocka

submission deadline 20 Feb 2027 | 4 articles | Viewed by 3517 | Submission Open

Keywords: chronic kidney disease; kidney function; kidney replacement therapy; kidney transplantation; kidney graft survival; post-transplant complications

(This special issue belongs to the Section Nephrology & Urology)

Advances in Anterior Cruciate Ligament Injury Treatment

edited by

Goran Vrgoč

submission deadline 20 Feb 2027 | 4 articles | Viewed by 3406 | Submission Open

Keywords: anterior cruciate ligament (ACL) injury; ACL reconstruction techniques; nonoperative ACL treatment; ACL graft; knee biomechanics; return-to-sport assessment; ACL rehabilitation; neuromuscular and proprioceptive training; athletic injuries; performance-enhancing substances; reinjury prevention; psychological readiness; ACL performance testing; osteoarthritis risk

(This special issue belongs to the Section Orthopedics)

Thoracic Surgery Today: Innovations, Challenges, and Future Perspectives

edited by Jeffrey B. Velotta and

Ory Wiesel

submission deadline 20 Feb 2027 | 4 articles | Viewed by 3047 | Submission Open

Keywords: thoracic surgery; minimally invasive thoracic surgery; innovation; esophageal surgery; robotic-assisted thoracic surgery; lung cancer; advanced techniques; thoracic surgical oncology; mediastinal surgery; mesothelioma surgery

(This special issue belongs to the Section General Surgery)

Current and Emerging Treatment Options in Chronic Liver Diseases

edited by Chandana B. Herath and Michael Praktiknjo

submission deadline 20 Feb 2027 | 2 articles | Viewed by 3016 | Submission Open

Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Technologies for Personalized Medicine in Head and Neck Surgery

edited by

Carlos Navarro-Cuéllar

and

José Luis Cebríán-Carretero

submission deadline 20 Feb 2027 | 4 articles | Viewed by 2873 | Submission Open

Keywords: personalized medicine; head and neck surgery; 3D printing; surgical navigation; artificial intelligence; computer-assisted surgery; regenerative medicine; precision oncology; craniofacial reconstruction; biomaterials; virtual surgical planning; genomics and proteomics; tissue engineering; functional rehabilitation

(This special issue belongs to the Section Otolaryngology)

Clinical Research Advances in Gynecologic Oncology

edited by

Maciej Skrzypczak

submission deadline 20 Feb 2027 | 2 articles | Viewed by 2843 | Submission Open

Keywords: ovarian cancer; endometrial cancer; breast cancer; molecular biology; gynecological cancers

(This special issue belongs to the Section Oncology)

Obsessive–Compulsive Disorder: Clinical Advances and Future Perspectives—Second Edition

edited by Andrea Fagiolini

submission deadline 20 Feb 2027 | 3 articles | Viewed by 2677 | Submission Open

Keywords: obsessions–compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

Clinical Advances and Future Challenges for Occupational Health

edited by

Gabriele D’Ettorre

and Vincenza Pellicani

submission deadline 20 Feb 2027 | 4 articles | Viewed by 2633 | Submission Open

Keywords: work-related disease; precision medicine; gender differences; aging workforce; preventive strategies

(This special issue belongs to the Section Epidemiology & Public Health)

Dental Care and Oral Health in Adolescents and Children

edited by

Karolina Gerreth

submission deadline 20 Feb 2027 | 2 articles | Viewed by 2532 | Submission Open

Keywords: oral health; oral diseases; diagnosis; dental treatment; treatment methods; general health; pediatric dentistry; special care dentistry; immunodeficiency; pediatric dental surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Therapeutic Advances in Hematological Malignancies: New Breakthroughs and Future Directions

edited by Seema Naik

submission deadline 20 Feb 2027 | 2 articles | Viewed by 2492 | Submission Open

Keywords: leukemia; lymphoma; myeloma; cell therapy; targeted therapy

(This special issue belongs to the Section Hematology)

Advances in Rhinosinusitis and Nasal Polyposis: From Emerging Trends and Therapeutic Opportunities to Surgery

edited by Gian Luca Fadda, Giovanni Cavallo and

Giuseppe Guida

submission deadline 20 Feb 2027 | 3 articles | Viewed by 2428 | Submission Open

Keywords: nasal polyps; chronic rhinosinusitis; asthma; endoscopic sinus surgery; anatomical variation; biologic treatment; type-2 inflammation; paranasal sinuses; CRSwNP; late response; long term; remission; dupilumab; control

(This special issue belongs to the Section Otolaryngology)

Chronic Kidney Disease: From Diagnosis to Treatment

edited by Debra Hain

submission deadline 20 Feb 2027 | 2 articles | Viewed by 2338 | Submission Open

Keywords: chronic kidney disease; type 2 diabetes; diabetic complications; hemodialysis; nephrology nursing; older adults; palliative care; therapy; hypertension

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances and Challenges in Liver Transplantation: 3rd Edition

edited by

Paola Aceto

submission deadline 20 Feb 2027 | 3 articles | Viewed by 2319 | Submission Open

Keywords: liver transplantation (LT); elderly donors; steatotic livers; donors after circulatory death (DCD); hepatocellular carcinoma (HCC); perioperative management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Management of Vitreous and Retinal Disorders

edited by Samuel Asanad

submission deadline 20 Feb 2027 | 2 articles | Viewed by 2198 | Submission Open

Keywords: OCT; OCTA; AMD; neurodegenerative disease; surgical techniques; retinal detachment; retinal blood flow; retinal biomarkers; gene therapy

(This special issue belongs to the Section Ophthalmology)

Arterial Stiffness and Cardiovascular Risk: New Advances and Challenges

edited by

Andrea Grillo

submission deadline 20 Feb 2027 | 3 articles | Viewed by 1859 | Submission Open

Keywords: arterial stiffness; vascular aging; anti-inflammation; cardiovascular risk; personalized medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Atrial Fibrillation: Screening, Management and Outcomes

edited by Ahmed AlTurki and Vidal Essebag

submission deadline 20 Feb 2027 | 2 articles | Viewed by 1854 | Submission Open

Keywords: atrial fibrillation; ablation; pulmonary vein isolation; atrial fibrillation screening; wearable devices; anti-arrhythmic drugs; cardiovascular outcomes; subclinical atrial fibrillation

(This special issue belongs to the Section Cardiology)

Diagnosis and Management of Corneal Diseases

edited by Nicola Cardascia

submission deadline 20 Feb 2027 | 2 articles | Viewed by 1769 | Submission Open

Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation

(This special issue belongs to the Section Ophthalmology)

New Insights into Transcatheter Mitral Valve Therapy

edited by Antonio Sisinni and

Rodrigo Estévez-Loureiro

submission deadline 20 Feb 2027 | 2 articles | Viewed by 1754 | Submission Open

Keywords: mitral regurgitation; transcatheter mitral valve therapy; TEER; TMVR; MitraClip; pascal; valve-in-valve; multimodality imaging; outcomes; structural heart interventions

(This special issue belongs to the Section Cardiovascular Medicine)

Cardiac Arrest: Beyond Survival—Precision Neuroprognostication After Cardiac Arrest

edited by

Chun-song Youn

submission deadline 20 Feb 2027 | 3 articles | Viewed by 1727 | Submission Open

Keywords: cardiac arrest; outcome; prognostication; targeted temperature management; post-cardiac arrest care

(This special issue belongs to the Section Cardiology)

Endoscopic Management of Pancreaticobiliary Disease: Updates and Future Directions

edited by

Keisuke Iwata

submission deadline 20 Feb 2027 | 3 articles | Viewed by 1628 | Submission Open

Keywords: pancreaticobiliary disease; ERCP; interventional EUS; tissue acquisition; early detection of pancreaticobiliary malignancy; management of AEs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Clinical Insights into Acute Respiratory Failure

edited by

Christophe Guervilly

submission deadline 20 Feb 2027 | 2 articles | Viewed by 1581 | Submission Open

Keywords: acute respiratory failure; pathophysiology; advances respiratory monitoring; respiratory support strategies; respiratory mechanics; mechanical ventilation; respiratory drive; patient-ventilator asynchrony

(This special issue belongs to the Section Intensive Care)

Clinical Advances in Endocarditis: From Diagnosis to Treatment

edited by Ram Sharony and Katia Orvin

submission deadline 20 Feb 2027 | 2 articles | Viewed by 1561 | Submission Open

Keywords: endocarditis; infective endocarditis; prosthetic valve endocarditis; TAVR endocarditis; advanced cardiac imaging

(This special issue belongs to the Section Cardiology)

Coronary Artery Disease in the Era of Artificial Intelligence: Clinical Insights and Therapeutic Challenges

edited by Konstantinos Mourouzis

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1558 | Submission Open

Keywords: coronary artery disease; myocardial ischemia; coronary imaging; revascularization; cardiometabolic risk; biomarkers; artificial intelligence; endothelial dysfunction; inflammation; arterial stiffness; antiplatelet therapy; heart failure; intraoperative graft verification

(This special issue belongs to the Section Cardiovascular Medicine)

Endoscopic Innovations in Gastrointestinal Diseases: From Diagnosis to Therapy

edited by Mattia Brigida and Gianluca Andrisani

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1544 | Submission Open

Keywords: endoscopic innovation; gastrointestinal diseases; advanced endoscopic imaging; therapeutic endoscopy; artificial intelligence; minimally invasive therapy; personalized medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Contemporary Issues and Emerging Trends in Colorectal Surgery

edited by

Marco Caricato

and

Gianluca Mascianà

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1519 | Submission Open

Keywords: abdominal surgery; minimally invasive surgery; colorectal surgery; colorectal cancer; inflammatory bowel disease; image-guided surgery; transational research; artificial intelligence; operative endoscopy; screening; early diagnosis; ERAS

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Neuroimmunological Disorders: Mechanisms and Therapies

edited by

Christos Bakirtzis

and

Marina Kleopatra Boziki

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1352 | Submission Open

Keywords: neuroinflammatory; multiple sclerosis; neuromyelitis optica spectrum disorders; mog associated disease; autoimmune/paraneoplastic encephalitis

(This special issue belongs to the Section Clinical Neurology)

Novel Insights into the Use of Artificial Intelligence in Clinical Medicine

edited by Sharon C. Kiang and Roger T. Tomihama

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1265 | Submission Open

Keywords: artificial intelligence; disease predictive models; wearable technology; surgical innovation; molecular targeting; big data science; machine learning; deep learning

Clinical Management Strategies for Coronary Artery Disease and Revascularization

edited by

Marco Spagnolo

submission deadline 20 Feb 2027 | 2 articles | Viewed by 1236 | Submission Open

Keywords: coronary artery disease; coronary revascularization; coronary physiology; coronary imaging; antithrombotic therapy

(This special issue belongs to the Section Cardiovascular Medicine)

Pharmacological Pain Management Advances

edited by Michael A. Ueberall

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1213 | Submission Open

Keywords: pain management; drug therapy; analgesics; co-analgesics; drug safety and drug interactions; real-world evidence

(This special issue belongs to the Section Anesthesiology)

Focus on Multiple Myeloma: Diagnosis, Therapy and Clinical Outcome

edited by

Martina Kleber

submission deadline 20 Feb 2027 | 1 articles | Viewed by 1094 | Submission Open

Keywords: multiple myeloma; novel therapies; treatment approach; prognosis; clinical outcome

(This special issue belongs to the Section Hematology)

Diet and Nutritional Aspects in Cardiovascular-Kidney-Metabolic Diseases (CKM)

edited by Krishnaswami Vijayaraghavan

submission deadline 20 Feb 2027 | 1 articles | Viewed by 993 | Submission Open

Keywords: cardiovascular-kidney-metabolic diseases (CKM); obesity; diabetes and metabolic syndrome; dietary factors; nutritional aspects; food policy and food security; chronic kidney disease; heart disease; technology

(This special issue belongs to the Section Clinical Nutrition & Dietetics)

Current and Emerging Management Strategies in Gynecologic Oncology

edited by Grzegorz Szewczyk

submission deadline 20 Feb 2027 | 2 articles | Viewed by 938 | Submission Open

Keywords: gynecologic oncology; surgical approach; molecular diagnostics; novel therapies; rare gynecological cancers; risk factors

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Frontiers in Myocardial Infarction: From Acute Revascularization to Long-Term Secondary Prevention

edited by

Nikolaos Stalikas

submission deadline 20 Feb 2027 | 1 articles | Viewed by 901 | Submission Open

Keywords: complete revascularization; myocardial infarction; vulnerable plaque; imaging guided PCI; biomarkers; secondary prevention; microvascular disease; endothelial dysfunction

(This special issue belongs to the Section Cardiology)

Robotic-Assisted Hepato-Pancreato-Biliary (HPB) Surgery: Advances and Clinical Perspectives

edited by

Michele Tedeschi

and Riccardo Memeo

submission deadline 20 Feb 2027 | 1 articles | Viewed by 850 | Submission Open

Keywords: liver surgery; pancreatic surgery; HPB surgery; robotic surgery; robotic systems; advances in HPB surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in the Field of Cariology

edited by

Aline Castilho

and

Frank Lippert

submission deadline 20 Feb 2027 | 1 articles | Viewed by 804 | Submission Open

Keywords: dental caries; caries diagnosis; caries risk assessment; minimally invasive dentistry; preventive strategies

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Pediatric Surgery—Current Hurdles and Future Perspectives—2nd Edition

edited by

Osnat Zmora

submission deadline 20 Feb 2027 | 1 articles | Viewed by 795 | Submission Open

Keywords: congenital anomalies; esophageal atresia; anorectal malformations; pediatric trauma; necrotizing enterocolitis; pediatric oncology; biliary atresia

(This special issue belongs to the Section Clinical Pediatrics)

Orthopedic Oncology Updates and Controversial Issues

edited by Yehuda Kollender and Ron Batash

submission deadline 20 Feb 2027 | Viewed by 792 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; oligometastatic; atypical behavior tumor; cryosurgery; rare diseases; surgery; radiation therapy; immunotherapy; chemotherapy

(This special issue belongs to the Section Orthopedics)

Regenerative and Biologic Therapies for Musculoskeletal Disorders

edited by

Diego Delgado

and

Mikel Sánchez

submission deadline 20 Feb 2027 | 1 articles | Viewed by 699 | Submission Open

Keywords: regenerative medicine; musculoskeletal disorders; cell-based therapy; platelet-rich plasma; extracellular vesicles; tissue engineering; osteoarthritis; tendon; cartilage; bone; skeletal muscle; translational research; preclinical research; clinical research

(This special issue belongs to the Section Orthopedics)

Clinical Research and Management of Infectious Diseases

edited by

Vasilis Petrakis

submission deadline 20 Feb 2027 | 1 articles | Viewed by 677 | Submission Open

Keywords: antimicrobial resistance (AMR); novel antibiotics; multidrug-resistant (MDR) pathogens; drug discovery and development; bacteriophage therapy; antimicrobial peptides; ESKAPE pathogens; antimicrobial stewardship

(This special issue belongs to the Section Infectious Diseases)

Advances in Pulmonary Embolism Therapeutics

edited by

Jeisson Osorio

submission deadline 20 Feb 2027 | 1 articles | Viewed by 573 | Submission Open

Keywords: acute pulmonary embolism; chronic pulmonary embolism; chronic thromboembolic disease; chronic thromboem-bolic pulmonary hypertension; catheter-directed therapy; pulmonary endarterectomy; balloon pulmonary angio-plasty

(This special issue belongs to the Section Vascular Medicine)

New Concepts in the Diagnosis and Treatment of Orthopedic Diseases in Children—2nd Edition

edited by

Sergio De Salvatore

and

Laura Ruzzini

submission deadline 20 Feb 2027 | Viewed by 464 | Submission Open

Keywords: pediatric orthopedics; flatfoot; genu valgum; genu varum; hip dysplasia; clubfoot; early onset scoliosis; Scheuermann disease; perthes; epiphysiolysis; scoliosis; pediatric trauma

(This special issue belongs to the Section Clinical Pediatrics)

Displaying special issue 751-800 on page 16 of 30.

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