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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Targeted Diagnosis and Treatment of Coronary Artery Disease: 2nd Edition

edited by

Antonio Nenna

submission deadline 15 Mar 2026 | 3 articles | Viewed by 6002 | Submission Open

Keywords: coronary artery disease; myocardial revascularization; percutaneous coronary intervention; cardiac surgery; coronary artery bypass graft; intravascular ultrasound; fractional flow reserve; instantaneous wave-free ratio; angiogenesis

(This special issue belongs to the Section Cardiology)

Updates on Brain Tumors: Diagnosis and Treatment

edited by Jigisha P. Thakkar and

Rimas V Lukas

submission deadline 15 Mar 2026 | 1 articles | Viewed by 5278 | Submission Open

Keywords: primary brain tumors; glioblastoma; IDH mutant glioma; meningioma; brain metastases; leptomeningeal disease

(This special issue belongs to the Section Clinical Neurology)

Clinical Applications of Endoscopic Technology in Gastroenterology

edited by

Naim Abu-Freha

submission deadline 15 Mar 2026 | 1 articles | Viewed by 2236 | Submission Open

Keywords: gastroscopy; colonoscopy; sedation; polyps; early detection; endoscopic submucosal dissection; mucosal resection; artificial intelligence in endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Novel Developments in Dental and Oral Surgery

edited by

Antonio Rapani

Teresa Lombardi

and

Federico Berton

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1577 | Submission Open

Keywords: guided bone regeneration; dental implant osseointegration; laser dentistry; maxillofacial reconstruction; sinus lift techniques

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Robot-Assisted Surgery: Current Trends and Future Perspectives

edited by

Francisco Miguel Sanchez-Margallo

and

Juan Alberto Sánchez-Margallo

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1572 | Submission Open

Keywords: robot-assisted surgery; surgical robotics; artificial intelligence in surgery; augmented reality; surgical ergonomics; minimally invasive surgery; haptic feedback

(This special issue belongs to the Section General Surgery)

Oral Hygiene: Updates and Clinical Progress: 2nd Edition

edited by

Frédéric Denis

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1334 | Submission Open

Keywords: periodontal disease; dental caries; plaque control; oral hygiene practices; gingivitis; dental prophylaxis; oral health education

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition

edited by

Luca Giovanella

and

Petra Petranović Ovčariček

submission deadline 15 Mar 2026 | 2 articles | Viewed by 1273 | Submission Open

Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism

(This special issue belongs to the Section Endocrinology & Metabolism)

Risk Prediction in Mechanical Circulatory Support (MCS) and Cardiac Transplantation

edited by

Nandini Nair

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1244 | Submission Open

Keywords: advanced heart failure; mechanical circulatory support (MCS); cardiac transplantation; heart transplantation; risk prediction

(This special issue belongs to the Section Cardiology)

Current Challenges and Future Directions in Lung Resections in Thoracic Surgery

edited by Vasileios K. Kouritas and Emmanuel Michael Kefaloyannis

submission deadline 15 Mar 2026 | 1 articles | Viewed by 1011 | Submission Open

Keywords: robotic-assisted thoracic surgery (RATS); robotic; sublobar; 3D; emphysema; endobronchial valves; lung volume reduction surgery (LVRS); high-risk; AI; research; lung; screening; lung cancer

(This special issue belongs to the Section General Surgery)

Latest Advances in Thoracic Surgery: 2nd Edition

edited by

Hideki Ujiie

submission deadline 15 Mar 2026 | 1 articles | Viewed by 831 | Submission Open

Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery

(This special issue belongs to the Section Respiratory Medicine)

Research Progress in Kawasaki Disease: Epidemiology, Treatment and Cardiovascular Outcomes

edited by Andre Jakob

submission deadline 15 Mar 2026 | 1 articles | Viewed by 758 | Submission Open

Keywords: Kawasaki disease; immune pathogenesis; immunomodulatory treatment; coronary artery pathology; cardiovascular outcomes

(This special issue belongs to the Section Clinical Pediatrics)

Cardiovascular Disease in MASLD: New Advances in Therapeutic Targets

edited by

Alfredo Caturano

submission deadline 15 Mar 2026 | Viewed by 119 | Submission Open

Keywords: MASLD; cardiovascular disease (CVD); metabolic dysfunction; steatotic liver disease; insulin resistance; dyslipidemia; atherosclerosis; inflammation; GLP-1 receptor agonists; SGLT2 inhibitors; lipid-lowering therapies; cardiometabolic risk; clinical trials; therapeutic targets

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Diagnosis and Treatment of Uveitis

edited by

Nenad Vukojević

submission deadline 15 Mar 2026 | Viewed by 105 | Submission Open

Keywords: uveitis; intraocular tumors; medical retina; pediatric retina

(This special issue belongs to the Section Ophthalmology)

Advances in Antithrombotic Therapy in Cardiovascular Medicine

edited by Daniele Giacoppo and Antonio Greco

submission deadline 15 Mar 2026 | Viewed by 94 | Submission Open

Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis

(This special issue belongs to the Section Cardiovascular Medicine)

Urologic Oncology: From Diagnosis to Treatment

edited by Matteo Vittori and Valerio Iacovelli

submission deadline 15 Mar 2026 | Viewed by 85 | Submission Open

Keywords: prostate cancer; kidney cancer; bladder cancer; testicular cancer

(This special issue belongs to the Section Nephrology & Urology)

Early-Stage Non-Small Cell Lung Cancer: Diagnostic Challenges and Therapeutic Innovations

edited by Efimia Boutsikou, Georgia F. Hardavella and

Kelly Domvri

submission deadline 15 Mar 2026 | Viewed by 84 | Submission Open

Keywords: non-small cell lung cancer (NSCLC); early-stage lung cancer; diagnostic imaging; stereotactic ablative radiotherapy (SABR); molecular profiling; adjuvant targeted therapy; immunotherapy in early-stage NSCLC

(This special issue belongs to the Section Respiratory Medicine)

Progress in Clinical Diagnosis and Therapy in Ophthalmology

edited by

Edward Wylegala

submission deadline 16 Mar 2026 | 2 articles | Viewed by 1251 | Submission Open

Keywords: ophthalmic imaging; artificial intelligence in ophthalmology; retinal diseases; corneal transplantation; glaucoma diagnostics; ocular therapeutics; personalized medicine; ocular genetics

(This special issue belongs to the Section Ophthalmology)

Movement Analysis in Rehabilitation

edited by Paola Contessa

submission deadline 16 Mar 2026 | Viewed by 108 | Submission Open

Keywords: clinical biomechanics; engineering methods; human movement; motor control; muscle force; musculoskeletal disorders; neuromuscular diseases; posture and balance; rehabilitation

(This special issue belongs to the Section Orthopedics)

Clinical Practices of Critical Care in Emergency Medicine

edited by

Gianni Turcato

submission deadline 17 Mar 2026 | 1 articles | Viewed by 1090 | Submission Open

Keywords: non-invasiveness; non-ICU critically ill patient; organ replacement versus organ support; prognostic assessment; vasopressors; inotropes; and vasoactive agents; emergency department

(This special issue belongs to the Section Intensive Care)

Neurocritical Care: Clinical Advances and Practice Updates: 2nd Edition

edited by Ali Seifi

submission deadline 18 Mar 2026 | Viewed by 171 | Submission Open

Keywords: traumatic brain injury (TBI); intracerebral hemorrhage (ICH); neurocritical care practice; neurocritical care; neurosurgical innovations; artificial intelligence; medical device and technology innovation in neurocritical care; stroke management; subarachnoid hemorrhage (SAH); status epilepticus

(This special issue belongs to the Section Clinical Neurology)

Clinical Perspectives in Stroke Rehabilitation

edited by Krystyna Jaracz,

Karolina Filipska-Blejder

and Robert Ślusarz

submission deadline 20 Mar 2026 | 9 articles | Viewed by 24034 | Submission Open

Keywords: stroke; clinical perspectives; therapy; functional outcome predictors; rehabilitation; quality of life

(This special issue belongs to the Section Clinical Rehabilitation)

Sleep in Neurology—Sleep Disorders and Dysfunction of the Nervous System

edited by

Mariusz Siemiński

submission deadline 20 Mar 2026 | 6 articles | Viewed by 18588 | Submission Open

Keywords: sleep; neurology; insomnia; restless leg syndrome; REM sleep behavior disorder; parasomnia; somnambulism; neurodegenerative disorders; brain injury; sleep-related movement disorders

(This special issue belongs to the Section Clinical Neurology)

Musculoskeletal Rehabilitation and Regenerative Medicine: Current Challenges and New Perspectives

edited by

Raffaele Vitiello

and Gianpaolo P. Ronconi

submission deadline 20 Mar 2026 | 5 articles | Viewed by 17434 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; enhanced recovery after surgery; chronic pain; disability; regenerative medicine; personalized medicine

(This special issue belongs to the Section Clinical Rehabilitation)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Mar 2026 | 6 articles | Viewed by 16970 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Moving Forward to New Trends in Pulmonary Diseases

edited by

Ramona Cioboata

and

Costin Teodor Streba

submission deadline 20 Mar 2026 | 6 articles | Viewed by 15711 | Submission Open

Keywords: pulmonary tuberculosis; chronic obstructive airway diseases; bronchiectasis; COVID-19; sleep apnea; ultrasound; lung cancer; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Risk Prediction for Gynecological Cancer

edited by

Federico Ferrari

submission deadline 20 Mar 2026 | 8 articles | Viewed by 14626 | Submission Open

Keywords: cervical cancer; endometrial cancer; tubo-ovarian cancer; diagnosis; treatment; prognosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Management of Prosthetic Joint Infection (PJI)

edited by Daniel Pérez-Prieto

submission deadline 20 Mar 2026 | 7 articles | Viewed by 12451 | Submission Open

Keywords: prosthetic joint infection; debridement; biofilm; wound healing; multidisciplinary team; osteomyelitis

(This special issue belongs to the Section Orthopedics)

Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation

edited by Young-Jin Seo

submission deadline 20 Mar 2026 | 9 articles | Viewed by 11814 | Submission Open

Keywords: anterior cruciate ligament (ACL); reconstruction; lateral extra-articular procedures; all-inside technique; internal bracing; slope reducing osteotomy; biologic augmentation; rehabilitation

(This special issue belongs to the Section Orthopedics)

Chronic Kidney Disease: Clinical Challenges and Management

edited by

Shuzo Kobayashi

and

Takayasu Ohtake

submission deadline 20 Mar 2026 | 5 articles | Viewed by 10440 | Submission Open

Keywords: chronic kidney disease; clinical trial; end-stage renal disease; kidney dysfunction; management; challenge

(This special issue belongs to the Section Nephrology & Urology)

Innovation in Hand Surgery

edited by Rocco De Vitis and Marco Passiatore

submission deadline 20 Mar 2026 | 7 articles | Viewed by 10416 | Submission Open

Keywords: hand surgery; hand reconstruction; hand deformities; reconstructive surgery; peripheral nerve surgery; hand tumors; thumb arthritis; wrist arthritis; arthroscopy; prosthesis

(This special issue belongs to the Section Orthopedics)

New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy

edited by

Marcos José Navarro-Santana

and Ignacio Cancela-Cilleruelo

submission deadline 20 Mar 2026 | 5 articles | Viewed by 9378 | Submission Open

Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 20 Mar 2026 | 3 articles | Viewed by 9233 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Mar 2026 | 8 articles | Viewed by 8897 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Innovations in the Treatment for Depression and Anxiety

edited by Lucie Bartova

submission deadline 20 Mar 2026 | 3 articles | Viewed by 8201 | Submission Open

Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance

(This special issue belongs to the Section Mental Health)

Surgical Treatment for Lung Cancer

edited by

Piotr Gabryel

, Cezary Piwkowski and Marek Ochman

submission deadline 20 Mar 2026 | 5 articles | Viewed by 7963 | Submission Open

Keywords: lung cancer; surgery; minimally invasive surgery; immunotherapy; enhanced recovery after surgery; segmentectomy

(This special issue belongs to the Section Respiratory Medicine)

Gastrointestinal Endoscopy: Clinical Advances in Diagnosis and Treatment, 2nd Edition

edited by Joao Santos-Antunes and

Tadateru Maehata

submission deadline 20 Mar 2026 | 2 articles | Viewed by 7561 | Submission Open

Keywords: diagnostic endoscopy; therapeutic endoscopy; gastrointestinal neoplasia; endoscopic mucosal resection; endoscopic submucosal dissection; early cancer; subepithelial lesions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions

edited by

Scipione Carerj

and Fausto Pizzino

submission deadline 20 Mar 2026 | 4 articles | Viewed by 7444 | Submission Open

Keywords: echocardiographic imaging; transcatheter intervention; aortic stenosis; mitral regurgitation; tricuspid regurgitation; left atrial appendage closure; patent foramen ovale closure; atrial septal defect repair

(This special issue belongs to the Section Cardiology)

Advanced Therapy for Heart Failure and Other Combined Diseases

edited by Gori Mauro and Marco Marini

submission deadline 20 Mar 2026 | 5 articles | Viewed by 6895 | Submission Open

Keywords: heart failure with reduced and preserved ejection fraction; advanced heart failure; inotropes; acute heart failure; GDMT

(This special issue belongs to the Section Cardiology)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Mar 2026 | 1 articles | Viewed by 6515 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Renal Cell Carcinoma: From Diagnostic to Therapy

edited by Ithaar H. Derweesh and Zachary A. Hamilton

submission deadline 20 Mar 2026 | 4 articles | Viewed by 6392 | Submission Open

Keywords: biomarkers; clinical practice patterns; diagnosis; kidney cancer; metastasis; renal cell carcinoma; renal mass; staging; systemic therapy; surveillance

(This special issue belongs to the Section Nephrology & Urology)

Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition

edited by Botond Csiky

submission deadline 20 Mar 2026 | 2 articles | Viewed by 5695 | Submission Open

Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease

(This special issue belongs to the Section Nephrology & Urology)

Psoriasis in Focus: Current Research, Treatments, and Future Directions

edited by

Tamara Gracia-Cazaña

and Josep Riera-Monroig

submission deadline 20 Mar 2026 | 5 articles | Viewed by 5579 | Submission Open

Keywords: psoriasis; biologic therapies; immunopathogenesis; precision medicine; comorbidities in psoriasis; psoriatic arthritis; phototherapy; topical treatments; systemic therapies

(This special issue belongs to the Section Dermatology)

Improving Diagnosis and Treatment of Vestibular Disorder: Latest Advances and Challenges

edited by

Enrico Armato

Andrea Castellucci

and Athanasia Korda

submission deadline 20 Mar 2026 | 2 articles | Viewed by 5500 | Submission Open

Keywords: vestibular system; balance disorders; dizziness; vertigo; vestibular testing; videonystagmography; video head impulse test; vestibular evoked myogenic potentials; vestibular rehabilitation therapy

(This special issue belongs to the Section Otolaryngology)

Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)

edited by

Pierluigi Carratù

submission deadline 20 Mar 2026 | 4 articles | Viewed by 5200 | Submission Open

Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk

(This special issue belongs to the Section Respiratory Medicine)

Advanced Approaches in Hip and Knee Arthroplasty

edited by Filippo Randelli and

Alberto Fioruzzi

submission deadline 20 Mar 2026 | 4 articles | Viewed by 4877 | Submission Open

Keywords: hip; hip surgery; knee arthroplasty; knee surgery; hip and knee arthroplasty

(This special issue belongs to the Section Orthopedics)

The Role of Scleral Lenses in the Management of Eye Disease

edited by Cherie B. Nau

submission deadline 20 Mar 2026 | 1 articles | Viewed by 4741 | Submission Open

Keywords: scleral lenses; corneal irregularity; corneal disease; dry eye disease; irregular astigmatism; keratoconus; meibomian gland dysfunction; midday fogging

(This special issue belongs to the Section Ophthalmology)

Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy

edited by

Athanasios Samaras

and

Andreas S. Papazoglou

submission deadline 20 Mar 2026 | 2 articles | Viewed by 4701 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology

(This special issue belongs to the Section Cardiology)

Clinical and Surgical Updates on Bariatric Surgery

edited by

Claudio Gambardella

submission deadline 20 Mar 2026 | 2 articles | Viewed by 4345 | Submission Open

Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD

(This special issue belongs to the Section General Surgery)

Clinical Advances in Kidney Transplantation

edited by

Florin Ioan Elec

and

Oana Antal

submission deadline 20 Mar 2026 | 3 articles | Viewed by 4268 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Mar 2026 | 3 articles | Viewed by 4235 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 651-700 on page 14 of 31.

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