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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Genetics and Breeding Research in Horticultural Crops

edited by

Hui Zhang

submission deadline 20 Aug 2025 | 3 articles | Viewed by 1353 | Submission Open

Keywords: horticultural crops; genomic sequencing; multi-omics technologies; molecular biology; gene editing; plant breeding; function of genes; molecular marker

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Toxicity Research of Biological Venoms

edited by

Karla De Castro Figueiredo Bordon

and Suely Vilela Sampaio

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1349 | Submission Open

Keywords: neurotoxicity assays; insect models; electrophysiology; screening assays; ion channels; therapeutic molecules; animal venoms; antitumoral activity; enzyme activity; biotechnological application

(This special issue belongs to the Section Molecular Toxicology)

New Insights into Embryonic Development

edited by

Jacek Z. Kubiak

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1346 | Submission Open

Keywords: embryonic development; molecular mechanisms; cellular mechanisms; model embryos; genetic

(This special issue belongs to the Section Molecular Biology)

Endothelial Function and Cardiovascular Disease: Molecular Advances and Challenges

edited by

Elena Grossini

submission deadline 20 Aug 2025 | 2 articles | Viewed by 1342 | Submission Open

Keywords: endothelium; heart; protection; therapeutic strategies; vascular system; vesicles

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathology and Novel Therapies for Lymphoma

edited by Fulvio Massaro

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1308 | Submission Open

Keywords: Hodgkin lymphoma; non-Hodgkin lymphoma; hematopathology; biomarker; new therapeutic approaches

(This special issue belongs to the Section Molecular Oncology)

Advanced Spectroscopy Research: New Findings and Perspectives

edited by

Marta Arczewska

submission deadline 20 Aug 2025 | Viewed by 1285 | Submission Open

Keywords: molecular spectroscopy; atomic spectroscopy; chemical analysis; molecular interaction; IR/FT-IR/ATR; Raman and SERS spectroscopy and imaging; UV-Vis; XRD; computational methods

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Cell Organelle Stress Responses and Implications in Human Diseases

edited by

Jaeseok Han

submission deadline 20 Aug 2025 | 2 articles | Viewed by 1267 | Submission Open

Keywords: organelle stresses; mitochondria; ER; lysosome; human diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cardioprotection in Drug-Induced Cardiotoxicity

edited by Roisin Kelly-Laubscher

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1263 | Submission Open

Keywords: cardioprotection; cardiotoxicity; anthracycline; cardiac dysfunction; heart failure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Bioactive Compounds in Human Diseases

edited by

Raju Dash

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1248 | Submission Open

Keywords: plant extracts; plant-derived compounds; secondary metabolites; mechanism of action; bioavailability; human health and disease; computer-aided drug design; machine learning and artificial Intelligence

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advance in Plant Abiotic Stress: 3rd Edition

edited by

De-Guo Han

and

Xingguo Li

submission deadline 20 Aug 2025 | 3 articles | Viewed by 1141 | Submission Open

Keywords: abiotic stress; cold; drought; salt; heat; nutrient deficiency; secondary metabolism; stress resistance; plant

(This special issue belongs to the Section Molecular Plant Sciences)

The Interplay Between Cellular Stress and Human Diseases

edited by

Daniele Vergara

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1137 | Submission Open

Keywords: cellular stress; DNA damage response; unfolded protein response; autophagy; senescence; apoptosis; repair pathways; mitochondrial stress; nutrient deprivation; oxidative stress

(This special issue belongs to the Section Biochemistry)

Research on Luminescent Materials and Their Luminescence Mechanism

edited by

María Teresa Colomer

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1076 | Submission Open

Keywords: luminescence; molecular/ionic level; mechanism

(This special issue belongs to the Section Materials Science)

Amyloid Hetero-Aggregation: 2nd Edition

edited by

Ludmilla A. Morozova-Roche

submission deadline 20 Aug 2025 | Viewed by 1073 | Submission Open

Keywords: amyloid; co-aggregation; hetero-aggregation; human proteins; bacterial amyloids; viral proteins; cytotoxicity; structure; function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Microsatellite Instability (MSI) and Mismatch Repair Deficient (dMMR)-Related Diseases: From Detection Methods to Practice

edited by Federica Zito Marino

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1053 | Submission Open

Keywords: microsatellite instability (MSI); mismatch repair deficient (dMMR); immunotherapy; next-generation sequencing (NGS); immunohistochemistry (IHC); polymerase chain reaction (PCR); MSI-positive tumors

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Phytochemicals in Antioxidation, Antimicrobial, and Cytoprotective Properties

edited by

Mihaela Niculae

submission deadline 20 Aug 2025 | 1 articles | Viewed by 941 | Submission Open

Keywords: phytochemicals; antioxidant; antimicrobial; cytoprotective; in vitro screening; in vivo evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular and Cellular Research on the Glioma and Tumor Microenvironment

edited by

Maria Beatrice Morelli

submission deadline 20 Aug 2025 | 2 articles | Viewed by 914 | Submission Open

Keywords: tumour microenvironment; immune cells; cell siganling; tumor niche; tumor heterogeneity; TMZ resistance; new therapeutic strategies; endothelial cells; fibroblasts; extracellular matrix

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights in Hepatic Disease and Hepatocellular Carcinoma

edited by

Soon Kyu Lee

and Jong-Young Choi

submission deadline 20 Aug 2025 | 1 articles | Viewed by 847 | Submission Open

Keywords: hepatology; viral hepatitis; liver cirrhosis; hepatocellular carcinoma; liver transplantation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Progression of Developing Novel Chiral Separation Materials, Chiral Selectors and Chiral Products

edited by István Ilisz

submission deadline 20 Aug 2025 | 1 articles | Viewed by 739 | Submission Open

Keywords: chirality; enantioselective separations; chiral selector molecules; chiral stationary phases; chiral sensors; enantiorecognition; chiral separation mechanisms

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Advances on Solubility and Diffusivity in Water-Based Systems and in Biological Media

edited by

Ana M. Mainar

and

José S. Urieta

submission deadline 20 Aug 2025 | 1 articles | Viewed by 737 | Submission Open

Keywords: water solubility ; water-solute interactions ; solvation; hydrophobic and hydrophilic effects ; improving water solubility and prediction ; solution of chemicals in biological media ; diffusivity ; drug transport and bioavailability; chemicals diffusivity across biological barriers

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Advances in Molecular Research of Kidney Diseases

edited by Andrea Angioi

submission deadline 20 Aug 2025 | Viewed by 735 | Submission Open

Keywords: molecular genetics; kidney disease; biomarkers; cellular signaling; target therapeutics; innovative treatments

(This special issue belongs to the Section Molecular Biology)

Exploring Organic Compounds in Photodynamic Therapy: Synthesis, Mechanism of Action and Biological Potential

edited by

Maria G. P. M. S. Neves

Nuno M. M. Moura

and

Catarina I. V. Ramos

submission deadline 20 Aug 2025 | 1 articles | Viewed by 729 | Submission Open

Keywords: organic photosensitizers; photodynamic therapy; synthetic strategies; mechanism of action; cancer cells; microorganisms

(This special issue belongs to the Section Biochemistry)

DNA-Based Vaccines Against Infectious Diseases and Cancer

edited by

Srinivasa Reddy Bonam

submission deadline 20 Aug 2025 | Viewed by 722 | Submission Open

Keywords: DNA vaccine; immune responses; infectious disease; plasmids; vaccine

(This special issue belongs to the Section Molecular Immunology)

Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease

edited by David Rohde

submission deadline 20 Aug 2025 | Viewed by 671 | Submission Open

Keywords: myocardial infarction; heart failure; atherosclerosis; arterial hypertension; myocarditis; arrhythmia; inflammation; hematopoiesis; myelopoiesis; tissue macrophages; neutrophil biology; lymphocytes; endothelial cells; megakaryocytes; platelet biology; biomarkers

(This special issue belongs to the Section Molecular Immunology)

New Insights into Autophagy and Retinal Degeneration

edited by

Francesco Fornai

submission deadline 20 Aug 2025 | 1 articles | Viewed by 655 | Submission Open

Keywords: autophagy; retinal degeneration; retinal inflammation; oxidative stress; retinal alterations; age-related macular degeneration; retinal damage; inflammatory processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Modulation of the Immune System and Oxidative Stress in Liver Illnesses

edited by

Vlad Pădureanu

and Dan Ionuț Gheonea

submission deadline 20 Aug 2025 | 1 articles | Viewed by 640 | Submission Open

Keywords: oxidative stress; liver illnesses; immune system; inflammatory

(This special issue belongs to the Section Molecular Immunology)

Nanomaterials in Immunology

edited by

Alexandru Mihai Grumezescu

submission deadline 20 Aug 2025 | 1 articles | Viewed by 626 | Submission Open

Keywords: nanomaterials; immunology; nanoparticles; drug delivery; cancer immunotherapy; immune modulation; vaccine adjuvants; immunotoxicity; autoimmune diseases; biocompatibility; nanotechnology in immune diseases; nanostructures in tissue engineering; nanomedicine; diagnostic nanomaterials; immune cell interaction

(This special issue belongs to the Section Molecular Nanoscience)

Precision Cancer Medicine: Molecular Insights, Biological Events and Clinical Perspectives

edited by

Dimitrios H. Roukos

submission deadline 20 Aug 2025 | Viewed by 625 | Submission Open

Keywords: multi-omics at bulk level; single-cell multi-omics; precision oncology; precision immune-oncology; tumor molecular profiling

(This special issue belongs to the Section Molecular Oncology)

Aging: From Molecular Mechanisms and Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Darío Acuña-Castroviejo

submission deadline 20 Aug 2025 | 1 articles | Viewed by 611 | Submission Open

Keywords: human aging; molecular clock; aging genes; epigenetics; nutrigenomics; inflammaging; stem cells; telomeres; mitochondria; brain-gut axis; brain-muscle axis; gut microbiota; chronodisruption

(This special issue belongs to the Section Molecular Biology)

Gynecological Oncology: From Molecular Basis to Therapy

edited by

Martin Götte

and Lars Hanker

submission deadline 20 Aug 2025 | 1 articles | Viewed by 586 | Submission Open

Keywords: gynecological oncology; molecular basis; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Lung Diseases and Lung Transplantations: Molecular Pathogenesis and Advanced Therapies

edited by Christopher Lambers

submission deadline 20 Aug 2025 | Viewed by 582 | Submission Open

Keywords: lung disease; lung transplantation; ECMO; EVLP; LAS; antibody-mediated rejection (AMR); CLAD; RAS/BOS; immunosuppression; pathogenesis; cell-free DNA; IPF therapies; gene therapies; stem cell therapies; immunotherapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights and Design Strategies for Carbonaceous Nanomaterials

edited by

Magdalena Krystyjan

and

Gohar Khachatryan

submission deadline 20 Aug 2025 | Viewed by 565 | Submission Open

Keywords: carbon nanomaterials; carbon (nano)fillers; graphene; carbon nanotubes; carbon quantum dots; nanoparticles; nanostructures

(This special issue belongs to the Section Molecular Nanoscience)

New Insights into the Pathobiology of T Cell Malignancies

edited by

Grzegorz Przybylski

submission deadline 20 Aug 2025 | Viewed by 564 | Submission Open

Keywords: T cell malignancies

(This special issue belongs to the Section Molecular Oncology)

Revolutionizing Antifungal Therapeutics: From Understanding to Intervention

edited by

Célia Fortuna Rodrigues

submission deadline 20 Aug 2025 | Viewed by 542 | Submission Open

Keywords: fungi; antifungal; biofilm; Candida; Aspergillus; Trichoderma

(This special issue belongs to the Section Molecular Microbiology)

Cellular and Molecular Mechanisms of Cardiovascular Repair

edited by

Isotta Chimenti

submission deadline 20 Aug 2025 | 1 articles | Viewed by 537 | Submission Open

Keywords: fibroblasts; injury repair; cardiac scar; extracellular matrix; fibrosis; angiogenesis; inflammation; cardioprotection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanistic and Small Molecule Discoveries for Therapeutic Advances in Hypertrophic and Dilated Cardiomyopathies

edited by Osha Roopnarine

submission deadline 20 Aug 2025 | Viewed by 535 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathies; cardiomyopathies

(This special issue belongs to the Section Molecular Pharmacology)

Physiological and Molecular Mechanisms of Abiotic Stresses in Crops

edited by

Yousef Alhaj Hamoud

submission deadline 20 Aug 2025 | Viewed by 517 | Submission Open

Keywords: abiotic stress; plant physiology; signaling pathways; plant molecular biology; resistance; crop yield and quality

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Advances in the Application of NMR Spectroscopy to Study Structure and Dynamics of Proteins

edited by Harindranath Kadavath

submission deadline 20 Aug 2025 | Viewed by 508 | Submission Open

Keywords: proteins; dynamics; NMR spectroscopy; structure– dynamics– function; protein folding; protein– protein interactions; in-cell NMR; biomolecular structure; intrinsically disordered proteins (IDPs)

(This special issue belongs to the Section Molecular Biology)

Drug Development Breakthroughs: From Novel Antimicrobials to Targeted Cancer Drugs

edited by

Christos Papaneophytou

submission deadline 20 Aug 2025 | Viewed by 502 | Submission Open

Keywords: drug development; molecular science; small-molecule inhibitors; biopharmaceuticals; peptides; cancer therapy

(This special issue belongs to the Section Molecular Pharmacology)

Mechanisms of Protein–Ligand Interactions in Therapies for Lifestyle Diseases and Their Complications

edited by Agnieszka Szkudlarek

submission deadline 20 Aug 2025 | Viewed by 470 | Submission Open

Keywords: chronic diseases and their complications; protein– ligand interactions; protein modifications; therapeutic efficacy; binding affinity; serum proteins; pharmaceutical applications; biomedical research

(This special issue belongs to the Section Molecular Biology)

The Role of Genome in Cancer Therapy

edited by Yoav Smith and Hovav Nechushtan

submission deadline 20 Aug 2025 | Viewed by 468 | Submission Open

Keywords: genome analysis; molecular therapy; drug resistance; cancer genetic

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms of Neurodegeneration and Neuroprotection for Retinal and Optic Nerve Diseases

edited by

Toshiyuki Oshitari

submission deadline 20 Aug 2025 | 1 articles | Viewed by 443 | Submission Open

Keywords: neuroprotection; neurodegeneration; neuronal cell death; regeneration; cell death and survival pathways; neurovascular unit; oxidative stress; inflammation; advanced glycation end products; ischemia; optic nerve injuries; glaucoma; optic neuritis; retinitis pigmentosa; diabetic retinopathy; age-related macular degeneration; retinal vein/artery occlusion; gene therapy; cell plantation; nutrients; neuroprotectants; drug delivery; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Yeast Models in Genetic and Molecular Research

edited by

Ee Sin Chen

submission deadline 20 Aug 2025 | Viewed by 439 | Submission Open

Keywords: yeast; genome; epigenetics; chemogenomics; DNA repair

(This special issue belongs to the Section Molecular Biology)

Molecular Studies of Hematologic Malignancies

edited by

Myunggon Ko

submission deadline 20 Aug 2025 | 1 articles | Viewed by 430 | Submission Open

Keywords: hematologic malignancies; molecular mechanisms; genetic and epigenetic aberrations; molecular diagnosis; targeted therapy and biomarkers

(This special issue belongs to the Section Molecular Oncology)

Solanaceae Biology: From Genetics to Metabolism

edited by

Pengxiang Fan

submission deadline 20 Aug 2025 | Viewed by 420 | Submission Open

Keywords: Solanaceae; nightshade family; tomato; potato; tobacco; eggplant; genetics; metabolism; crop improvement; specialized metabolite

(This special issue belongs to the Section Molecular Plant Sciences)

Cancer Immunotherapy Biomarkers

edited by Ilias P. Nikas,

Ioannis Pateras

and

Apostolos Zaravinos

submission deadline 20 Aug 2025 | Viewed by 411 | Submission Open

Keywords: tumor microenvironment; tumor immunology; cancer biomarkers; immunotherapy; immunohistochemistry; pathology; personalized medicine; omics technologies; prognosis and therapy; bioinformatics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular Senescence as a Therapeutic Target in Cancer: Mechanisms, Challenges, and Therapeutic Opportunities

edited by

Mi Kyung Park

submission deadline 20 Aug 2025 | Viewed by 407 | Submission Open

Keywords: cellular senescence; cancer therapy; therapeutic targeting; senolytic drugs; senescence-associated secretory phenotype (SASP)

(This special issue belongs to the Section Molecular Oncology)

Cellular Senescence and the Senescence-Associated Secretory Phenotype (SASP) in Age-Related Diseases

edited by Jordi Olloquequi

submission deadline 20 Aug 2025 | Viewed by 400 | Submission Open

Keywords: cellular senescence; senescence-associated secretory phenotype (SASP); age-related diseases; atherosclerosis; chronic obstructive pulmonary disease (COPD); type 2 diabetes mellitus (T2DM); non-alcoholic fatty liver disease (NAFLD); Alzheimer’ s disease (AD); inflammation; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Experimental Models and Applications in Muscle Regeneration

edited by

Daiva Bironaite

submission deadline 20 Aug 2025 | Viewed by 395 | Submission Open

Keywords: stem cells; internal and external stimuli; scaffolds; signaling systems; muscle regeneration mechanisms

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Aug 2025 | 1 articles | Viewed by 394 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

Exploring the Impact of the Biological Clock on Health and Disease

edited by

Bojlul Bahar

submission deadline 20 Aug 2025 | Viewed by 390 | Submission Open

Keywords: circadian rhythm; inflammation; oxidative stress; energy balance; metabolic syndrome; ageing; cancer; diabetes; obesity; entrainment; synchrony; melatonin

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 901-950 on page 19 of 68.

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