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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Protein–RNA Interactions: Function, Mechanism, and Identification
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 4493 | Submission Open
Keywords: RNA-binding protein (RBP); protein– RNA interaction; RNA structure; RNA processing; RNA stability; RNA modification; translation; gene regulatory network
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Pathogenesis, Molecular Mechanisms, and Therapeutic Strategies for Neurodegenerative Diseases
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 4479 | Submission Open
Keywords: neurodegeneration; molecular pathways; protein aggregation; gene therapy; neuroprotection
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Induced Pluripotent Stem and Extracellular Vesicles in Biomedicine submission deadline 20 Aug 2025 | 1 articles | Viewed by 4476 | Submission Open
Keywords: induced pluripotent stem; embryonic stem cells; extracellular vesicles; tissue development; translational medicine
(This special issue belongs to the Section Molecular Biology)
Molecular Scale Design, Synthesis, and Application of Macroporous, Mesoporous, and Microporous Materials submission deadline 20 Aug 2025 | 4 articles | Viewed by 4406 | Submission Open
Keywords: macro-; meso- and microporous; porous materials; molecular design; adsorption; porous organic frameworks
(This special issue belongs to the Section Materials Science)
Molecular Advances in Liposome-Based Drug Delivery Systems
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 4324 | Submission Open
Keywords: liposomes; targeted delivery; controlled release; nanotechnology; drug delivery; diagnostics; therapeutics; multifunctional liposomes; phospholipids
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Therapeutic Strategies in Allergic Diseases
edited by
submission deadline 20 Aug 2025 | 5 articles | Viewed by 4284 | Submission Open
Keywords: molecular allergy diagnostics; allergen identification; allergen neutralization/elimination strategies; allergen immunotherapy; impact of pollution on allergies; new allergens; cross-reactivity; unexpected allergen sources
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Bioactive Molecules submission deadline 20 Aug 2025 | 3 articles | Viewed by 4268 | Submission Open
Keywords: antimicrobial profile; drug discovery; tissue regeneration; analytical techniques; chemical synthesis; high-throughput screening; therapeutic development; surface functionalization; biomaterial integration; bio-based
(This special issue belongs to the Section Molecular Biology)
Natural Products: New Insights into Overcoming Oxidative Stress in Pathological Diseases
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 4257 | Submission Open
Keywords: natural products; nutraceuticals; oxidative stress; antioxidants; ROS; redox signaling; oxidative stress; pathological diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Ion Channels in Eye Development, Health, and Disease
edited by Thirumalini Vaithianathan and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 4227 | Submission Open
Keywords: eye development; eye health and disease; ion channels; channelopathies; physiology; computational technology; molecular modeling; molecular biology tools; pharmacology; systems genetics
(This special issue belongs to the Section Molecular Biology)
Targeting Oxidative Stress for Disease: 2nd Edition submission deadline 20 Aug 2025 | 5 articles | Viewed by 4208 | Submission Open
Keywords: oxidants and free radical production; physiological activities of free radicals; detrimental effects of free radicals on human health; ROS and ROS-mediated cellular signaling; pathophysiology of oxidative stress; biomarkers of oxidative stress; chronic degenerative diseases; therapeutic approaches targeting oxidative stress; biochemical/molecular targets of chronic diseases; exogenous antioxidants and human health; flavonoids and redox biology in the pathophysiology of diseases; pro-oxidative role of antioxidants: double-sided sword; prooxidant agents in therapy
(This special issue belongs to the Section Molecular Biology)
Characteristics of Microorganisms Colonizing Animals and Alternative Methods of Infection Control in the Light of the “One Health” Concept
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 4192 | Submission Open
Keywords: zoonotic pathogens; virulence traits; antimicrobial resistance; molecular environment of resistance genes; whole-genome sequencing; microbiome; probiotics; alternative methods of combating pathogens in animals
(This special issue belongs to the Section Molecular Microbiology)
The Role of Extracellular Vesicles in Inflammatory Diseases
edited by Kaushik Das
submission deadline 20 Aug 2025 | 5 articles | Viewed by 4173 | Submission Open
Keywords: extracellular vesicles; inflammation; inflammatory diseases; pathogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in the Pathophysiology and Treatment of Diabetic Retinopathy
edited by Federico Gonzalez-Fernandez and
submission deadline 20 Aug 2025 | 3 articles | Viewed by 4142 | Submission Open
Keywords: diabetic retinopathy; age-related macular degenerations; retinal; vascular endothelial growth factor; visual system
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Engineering in Dental Restorative and Regenerative Materials
edited by
submission deadline 20 Aug 2025 | 5 articles | Viewed by 4136 | Submission Open
Keywords: dental composites; ceramics; additive manufacturing; dental adhesives; bioactive; 3D printing; photopolymerization; curing devices; microstructure; degree of conversion; bulk-fill composites; lasers in dentistry; infrared spectroscopy; biocompatibility; bone regeneration; osseointegration; soft tissue regeneration
(This special issue belongs to the Section Materials Science)
Advanced Therapy Using Human Mesenchymal Stem Cells (MSCs) and MSC Extracellular Vesicles
edited by Tong Ming Liu and Xiaoman Luo
submission deadline 20 Aug 2025 | 1 articles | Viewed by 4130 | Submission Open
Keywords: mesenchymal stem cells; extracellular vesicles; MSCs; MSC-EVs; regenerative medicine
(This special issue belongs to the Section Molecular Biology)
Functional Analysis and Therapeutic Targets of Long Non-Coding RNAs
edited by Hidenori Tani
submission deadline 20 Aug 2025 | 2 articles | Viewed by 4111 | Submission Open
Keywords: lncRNAs; gene expression; cellular processes; disease dysregulation; therapeutic targets; functional analysis; lncRNA therapeutics; lncRNA modulation; stability; localization
(This special issue belongs to the Section Molecular Genetics and Genomics)
Recent Research of Phytochemicals in Health and Disease
edited by Sachiko Koyama, and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 4107 | Submission Open
Keywords: phytochemicals with bioactive properties; health; brain function; regeneration; wound healing; treatment; and prevention of diseases; delivery routes and delivery methods; formulation of phytochemicals to overcome their hydrophobic nature and enhance their stability; drugs; supplements to drugs; and supplements for health maintenance; nourishment and phytochemicals; drug side effects; COVID-19
(This special issue belongs to the Section Bioactives and Nutraceuticals)
From Diagnosis to Treatment of Haematological Neoplasms submission deadline 20 Aug 2025 | 2 articles | Viewed by 3992 | Submission Open
Keywords: haematological neoplasms; biomarkers; precision medicine
(This special issue belongs to the Section Molecular Oncology)
Bioactive Polymer-Based Materials Dedicated to Wound Healing submission deadline 20 Aug 2025 | 2 articles | Viewed by 3861 | Submission Open
Keywords: wound healing; polymer; bioactive materials; tissue engineering; biomaterials; thin films; scaffolds; hydrogels
(This special issue belongs to the Section Materials Science)
Stem Cells in Human Health and Diseases
edited by Dana Yehudai-Ofir
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3843 | Submission Open
Keywords: stem cells; stem cell biology; stem-cell-based therapy; stem cell regulation; cancer stem cell; tumor-initiating cell  
(This special issue belongs to the Section Molecular Immunology)
Advances in Tea Tree Genetics and Breeding: 2nd Edition
edited by and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3831 | Submission Open
Keywords: tea plant (Camellia sinensis); molecular mechanism; secondary metabolites; stress response; quality-related component; genes identification; QTL mapping; molecular functional markers
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms and Therapies of Brain Tumors
edited by Oana Alexandru
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3696 | Submission Open
Keywords: brain tumors; molecular mechanisms; signal transduction; cell proliferation; apoptosis; targeted therapies; chemotherapy; radiotherapy
(This special issue belongs to the Section Molecular Oncology)
Myocardial Disease: Molecular Pathology and Treatments
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 3694 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; amyloidosis; myocarditis; sarcoidosis; genetic abnormalities; immune mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research Progress of Cereal Crop Disease Resistance
edited by and Zhenqi Su
submission deadline 20 Aug 2025 | 3 articles | Viewed by 3679 | Submission Open
Keywords: cereal crops; disease resistance; resistance genes; breeding; molecular marker-assisted selection; molecular regulatory network
(This special issue belongs to the Section Molecular Plant Sciences)
Male Genitourinary Tumors: Molecular and Cellular Mechanism
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3670 | Submission Open
Keywords: penile carcinoma; tumor biology; immune modulator; HPV   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bacteriophage: Molecular Ecology and Pharmacology, 2nd Edition
edited by , and Richard Allen White III
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3584 | Submission Open
Keywords: bacteriophage ecology; bacteriophage pharmacology; intercell communication of bacteria; phage-host interactions; phage-host recognition; phage receptors; phage therapy
(This special issue belongs to the Section Molecular Microbiology)
Big Data in Multi-Omics submission deadline 20 Aug 2025 | 2 articles | Viewed by 3552 | Submission Open
Keywords: data science; big data; omics; data management; data analytics TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in Shona   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate Shona to Simplified Chinese Never translate Shona Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Informatics)
Pharmacological Activities of Secondary Metabolites and Derivates of Medicinal Plants Around the World, 2nd Edition
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3544 | Submission Open
Keywords: natural products; secondary metabolites; medicinal chemistry; worldwide traditional medicine; isolation and identification of secondary metabolites; experimental studies; photochemistry; pharmacognosy; medicinal plants
(This special issue belongs to the Section Molecular Pharmacology)
Cyclodextrin-Based Polymer Systems for Biomedical Applications submission deadline 20 Aug 2025 | 1 articles | Viewed by 3508 | Submission Open
Keywords: cyclodextrins; polymers; grafting; drug delivery; hydrophobic drugs; wound healing; tissue engineering; antimicrobial systems; supramolecular systems
(This special issue belongs to the Section Macromolecules)
Molecular Research on Diabetes and Obesity
edited by
submission deadline 20 Aug 2025 | 3 articles | Viewed by 3498 | Submission Open
Keywords: obesity; diabetes; hypothalamus; insulin resistance; glucose homeostasis; lipid metabolism; adipose tissue; cardiovascular tissue
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Cellular and Molecular Mechanisms of Acute Lung Injury submission deadline 20 Aug 2025 | 3 articles | Viewed by 3480 | Submission Open
Keywords: acute lung injury; lung infection; acute respiratory distress syndrom; neutrophil-mediated immune response; alveolar epithelial injury; pulmonary oedema
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Functional Genomics in Translational Medicine
edited by , Oana Zanoaga and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3459 | Submission Open
Keywords: functional genomics; omics approaches; drug response/resistance; therapeutic targets; genomics and transcriptomic alteration; bioinformatic analysis; data integration; human disease; personalized medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Role of the IGF Axis in Disease, 4th Edition
edited by Claire M. Perks
submission deadline 20 Aug 2025 | 3 articles | Viewed by 3448 | Submission Open
Keywords: IGF axis; cancer; obesity; hallmarks of cancer
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Natural Products in Obesity: Novel Strategies and Molecular Mechanisms: 2nd Edition
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3383 | Submission Open
Keywords: obesity; inflammation; white adipose tissue; adipogenesis; oxidative stress; metabolic disease; molecular mechanisms
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Regulation and Application of Bioactive Metabolites in Plants
edited by and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3365 | Submission Open
Keywords: medicinal plants; biosynthesis; biological activity; regulation; pharmacological mechanism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Pharmacology of Medicinal Plants
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3354 | Submission Open
Keywords: medicinal plants; drug development; molecular pharmacology; clinical phytopharmacology
(This special issue belongs to the Section Molecular Pharmacology)
Anxiolytic or Antidepressant Activity from Active Principles in Medicinal Plants
edited by Carolina López-Rubalcava and Erika Estrada Camarena
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3347 | Submission Open
Keywords: phytopharmacology; anxiety; depression; medicinal plants; animal models
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Signaling Transduction in Health and Disease
edited by and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 3281 | Submission Open
Keywords: signaling pathways; inflammation; human disease; oxidative stress; neurodegeneration; heart disease; antioxidants
(This special issue belongs to the Section Biochemistry)
Current Research on Plants as Natural Antioxidants
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3177 | Submission Open
Keywords: plant-derived antioxidant; natural products; polyphenols; oxidative stress
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advancing Climate Resilience in Horticultural Crops Through Omics Technologies
edited by and
submission deadline 20 Aug 2025 | 3 articles | Viewed by 3133 | Submission Open
Keywords: horticultural crops; climate change; omics technologies; stress responses; abiotic stresses; food security; agricultural sustainability; genomics; transcriptomic; proteomics
(This special issue belongs to the Section Molecular Plant Sciences)
Lipid Metabolism in Human Health and Diseases
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3120 | Submission Open
Keywords: lipids; fatty acids; lipid metabolism; metabolic disorders; cardiovascular diseases; neurodegenerative diseases; cancers
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Synthesis, Characterization and Application of Metal and Metal Oxide Nanomaterials submission deadline 20 Aug 2025 | 2 articles | Viewed by 3118 | Submission Open
Keywords: metal nanoparticles; metal nanoclusters; properties of metal nanostructures; optical sensing and bio-sensing; pollutant sensing; metal oxide-based materials; photocatalysis; decomposition of pollutants by photocatalysis; energy production; conversion; and storage; water treatment
(This special issue belongs to the Section Molecular Nanoscience)
Inflammatory Bowel Disease: Focus on Molecular Research
edited by David Meriwether and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3099 | Submission Open
Keywords: inflammatory bowel disease; gut microbiota; genomic sequencing; proteomic; lipidomic; metabolomic; therapy; biomarker; animal and organoid model  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Antibody–Drug Conjugates
edited by Bing Sun
submission deadline 20 Aug 2025 | 1 articles | Viewed by 3095 | Submission Open
Keywords: antibody– drug conjugate (ADC); cancer treatment; non-oncology indications; antibody selection; payload; linker; conjugation chemistry
(This special issue belongs to the Section Molecular Immunology)
Genetic and Epigenetic Mechanisms in Growth and Neurodevelopmental Disorders
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 3048 | Submission Open
Keywords: growth defects; intellectual disability; epilepsy; autism spectrum disorders; epigenetic variations; copy number variations; next generation sequencing
(This special issue belongs to the Section Molecular Genetics and Genomics)
Cellular and Molecular Mechanisms in Oxidative Stress-Related Diseases, 4th Edition submission deadline 20 Aug 2025 | 3 articles | Viewed by 3048 | Submission Open
Keywords: molecular targets of oxidative stress in oxidative stress related-diseases; oxidative stress and oxidative stress-related pathologies; cellular response to oxidative stress; oxidative stress and apoptosis in oxidative stress-related diseases; oxidative stress and related cell signaling; cell adaptation to oxidative stress; biomarkers of oxidative stress in disease; beneficial effects of natural or synthetic antioxidants in oxidative stress-related diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into the Immunopathology of Autoimmune and Drug Induced Liver Injury
edited by Eleni Geladari
submission deadline 20 Aug 2025 | 2 articles | Viewed by 3037 | Submission Open
Keywords: liver disease; liver injury; immune system; immune dysregulation
(This special issue belongs to the Section Molecular Immunology)
Chronic Pain: Diagnosis, Pathophysiological Mechanisms and Treatment
edited by and Thomas Herdegen
submission deadline 20 Aug 2025 | 3 articles | Viewed by 3022 | Submission Open
Keywords: chronic pain; sex differences; age differences; pain therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Computational Biology: Molecular Dynamics Simulation of Biomolecules submission deadline 20 Aug 2025 | 1 articles | Viewed by 2981 | Submission Open
Keywords: computational biology; molecular dynamics; molecular simulation of rare diseases; computational design of antimicrobials; computational design of antivirals; molecular simulation of cancer-related processes; computational design of anti-cancer molecules; molecular simulation of biotechnology processes
(This special issue belongs to the Section Molecular Informatics)
Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition submission deadline 20 Aug 2025 | 2 articles | Viewed by 2977 | Submission Open
Keywords: IBD; dietary bioactive compounds; molecular mechanisms; health promotion; prevention; antioxidant; anti-inflammatory; nutritional support
(This special issue belongs to the Section Bioactives and Nutraceuticals)
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