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Functional Analysis and Therapeutic Targets of Long Non-coding RNAs

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 288

Special Issue Editor

E-Mail Website
Guest Editor
Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano, Totsuka, Yokohama, Japan
Interests: RNA biology; long noncoding RNA; drug discovery

Special Issue Information

Dear Colleagues,

Long non-coding RNAs (lncRNAs) have emerged as crucial regulators of gene expression and cellular processes, with their dysregulation being implicated in various human diseases. Consequently, lncRNAs have gained significant attention as promising therapeutic targets. The aim of this Special Issue is to provide a comprehensive overview of the latest advances in the functional analysis and therapeutic targeting of lncRNAs, with a particular emphasis on the development of novel lncRNA-based therapies.

We welcome original research articles and review manuscripts addressing the following two topics: (a) lncRNA-targeted therapeutics: This Special Issue will highlight the development of novel therapeutic strategies targeting lncRNAs, including approaches that modulate lncRNA function, stability, and localization. (b) lncRNA-based therapeutic modalities: Submissions exploring a wide range of therapeutic modalities for targeting lncRNAs, such as antisense oligonucleotides, small interfering RNAs (siRNAs), CRISPR/Cas9 gene editing, and small-molecule modulators, are highly encouraged. It is believed that this Special Issue will serve as a valuable resource for researchers and clinicians working in the field of lncRNA biology and therapeutics.

Dr. Hidenori Tani
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • lncRNAs
  • gene expression
  • cellular processes
  • disease dysregulation
  • therapeutic targets
  • functional analysis
  • lncRNA therapeutics
  • lncRNA modulation
  • stability
  • localization

Published Papers

This special issue is now open for submission.
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