Protein–RNA Interactions: Function, Mechanism, and Identification
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 3871
Special Issue Editor
2. Center for Life Nano- and Neuro-Science, RNA Systems Biology Lab, Fondazione Istituto Italiano di Tecnologia (IIT), 00161 Rome, Italy
Interests: bioinformatics; macromolecular interaction; next-generation sequencing; non-coding RNA; RNA-binding protein; gene regulatory network
Special Issue Information
Dear Colleagues,
Protein–RNA interactions (PRIs) are fundamental to all cellular processes, playing a critical role in gene expression, RNA processing, and protein synthesis. These interactions are mediated by RNA-binding proteins (RBPs) that recognize specific RNA targets through their sequences, structures, and modifications. Understanding these interactions is essential for deciphering the complex regulatory networks that govern cellular function.
We are pleased to invite you to submit your work to this Special Issue of IJMS focused on the intricate interplay between proteins and RNA molecules. This Special Issue aims to delve into the multifaceted functions and mechanisms underlying PRIs, while also showcasing innovative techniques for their identification.
In this Special Issue, original research articles and reviews are welcome. Topics of interest include, but are not limited to, the following:
- Functional roles of RBP-RNA interactions in gene expression regulation;
- Mechanisms governing protein–RNA recognition and RBP specificity;
- Experimental and computational methodologies for identifying PRIs;
- The impact of PRIs on RNA processing, stability, and translation;
- The dysregulation of PRIs in human diseases and development;
- Therapeutic strategies targeting aberrant PRIs.
Looking forward to receiving your contributions.
Dr. Alessio Colantoni
Guest Editor
Manuscript Submission Information
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Keywords
- RNA-binding protein (RBP)
- protein–RNA interaction
- RNA structure
- RNA processing
- RNA stability
- RNA modification
- translation
- gene regulatory network
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