International Journal of Molecular Sciences

Molecular Mechanisms Underlying Abiotic Stress Tolerance in Plants: From Gene Regulation to Adaptive Traits

edited by Shijiang Cao

submission deadline 20 Feb 2027 | 2 articles | Viewed by 2170 | Submission Open

Keywords: forest molecular biology; tree physiology; plant developmental biology; plant-microbe interactions; abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Crop Stress: From Genomic Mechanisms to Breeding

edited by Meng Jiang

submission deadline 20 Feb 2027 | Viewed by 62 | Submission Open

Keywords: crop stress; molecular mechanisms; genomics; stress signaling; transcription factors; gene editing; molecular breeding; multi-omics; climate resilience; functional genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Oxidative Stress-Driven Pathophysiological Dysregulation

edited by

Gaia Favero

and

Luca Vanella

submission deadline 20 Feb 2027 | Viewed by 51 | Submission Open

Keywords: oxidative stress; inflammation; reactive oxygen species; antioxidants

(This special issue belongs to the Section Molecular Biology)

Sleep Apnea and Sleep-Disordered Breathing

edited by

Kazufumi Nakamura

submission deadline 20 Feb 2027 | Viewed by 42 | Submission Open

Keywords: sleep apnea; sleep-disordered breathing; intermittent hypoxia; oxidative stress; inflammation; biomarkers; molecular mechanisms; cardiovascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Epigenetic and Transcriptional Dysregulation in Cancer and Therapeutic Opportunities

edited by

Yi Chen

submission deadline 25 Feb 2027 | Viewed by 207 | Submission Open

Keywords: cancer epigenetics; transcriptional dysregulation; chromatin remodeling; DNA methylation; histone modifications; epigenetic therapy; oncogenic transcription factors; tumor progression

(This special issue belongs to the Section Molecular Oncology)

Microbial Bioinformatics and Genomics

edited by Darío Augusto Fernández do Porto and María Mercedes Palomino

submission deadline 25 Feb 2027 | Viewed by 104 | Submission Open

Keywords: microbial genomics; bioinformatics; metagenomics; antimicrobial resistance; pathogen evolution; multi-omics; systems biology; structural bioinformatics; artificial intelligence; drug discovery

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biofunctionality of Bioactives from Agri-Food Industrial Sources

edited by

Yanina E. Rossi

submission deadline 25 Feb 2027 | Viewed by 79 | Submission Open

Keywords: bioactive compounds; oxidative stress; inflammation process; cellular and animal models; functional ingredients

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Microbiome as the Diagnostic Biomarker in Non-Communicable Diseases

edited by

Pisut Pongchaikul

submission deadline 25 Feb 2027 | Viewed by 66 | Submission Open

Keywords: microbiome; non-communicable diseases; molecular signatures; multi-omics; diagnostic biomarker

(This special issue belongs to the Section Molecular Microbiology)

The Role of Structural and Computational Biology in Elucidating Biomolecular Mechanisms

edited by

Luigi Vitagliano

and

Nicole Balasco

submission deadline 25 Feb 2027 | Viewed by 51 | Submission Open

Keywords: structural basis of disease; integrated structural biology; structure–function relationships; proteins and peptides; molecular design; nucleic acids

(This special issue belongs to the Section Macromolecules)

From Waste to Product: End-Use-Oriented Valorization of Plant-Based Agro-Industrial Residues Through Analytical Approaches

edited by

Roberto Berni

and Alfonso Trezza

submission deadline 26 Feb 2027 | Viewed by 167 | Submission Open

Keywords: waste-to-product; agro-industrial waste; plant by-products; -omics; material characterization; structure-function relationships; bioactive compounds; lignocellulosic biomass; biorefinery; green extraction technologies; circular economy; functional ingredients; biomaterials

(This special issue belongs to the Section Molecular Plant Sciences)

Analysis of Plant Resistance Mechanisms for Crop Biological Breeding

edited by

Xiaofeng Su

submission deadline 26 Feb 2027 | Viewed by 108 | Submission Open

Keywords: biological breeding; omics analysis; regulatory network; molecular mechanism; gene editing

(This special issue belongs to the Section Molecular Plant Sciences)

25th Anniversary of IJMS: Advances in Molecular Endocrinology and Metabolism

edited by

José L. Quiles

submission deadline 28 Feb 2027 | 28 articles | Viewed by 64888 | Submission Open

Keywords: molecular endocrinology; metabolic diseases; hormonal regulation; systems biology; precision medicine

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

25th Anniversary of IJMS: Updates and Advances in Molecular Microbiology

edited by

Shu Yuan

submission deadline 28 Feb 2027 | 24 articles | Viewed by 38534 | Submission Open

Keywords: bacteria fungi; bacteriophages; microalgae; microbiome; gut microbiota; environmental microbiome; microbiome–brain–gut axis; virus–host interactions; emerging viruses re-emerging viruses; virus mutation; biofilm antimicrobial; SARS-CoV-2 (COVID-19)

(This special issue belongs to the Section Molecular Microbiology)

IJMS 25th Anniversary: Updates and Progress on Bioactives and Nutraceuticals

edited by

Maurizio Battino

submission deadline 28 Feb 2027 | 11 articles | Viewed by 21997 | Submission Open

Keywords: natural products; bioactive; nutraceutical; nutrient; health; dietary; functional food; vitamins; phytochemicals

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Metals and Metal Ions in Human Health, Diseases, and Environment

edited by

Agnieszka Scibior

,

Juan Llopis

and

Manuel Aureliano

submission deadline 28 Feb 2027 | 7 articles | Viewed by 17967 | Submission Open

Keywords: metal toxicity; metal-based drugs; polyoxometalates; protein metalation; human health problems; diseases; in vitro/in vivo studies; human studies; environmental pollution

(This special issue belongs to the Section Molecular Biology)

25th Anniversary of IJMS: Updates and Advances in Macromolecules

edited by

Haiyang Gao

,

Salah-Eddine Stiriba

and

Zhongzhou Chen

submission deadline 28 Feb 2027 | 6 articles | Viewed by 16940 | Submission Open

Keywords: macromolecules; monomers; lipids; peptides; proteins; carbohydrates; polysaccharides; nucleic acids; modification; functionalization; structure–property relationship

(This special issue belongs to the Section Macromolecules)

Challenges and Future Perspectives in Treatment for Lung Cancer: 2nd Edition

edited by Ilaria Marrocco and

Donatella Romaniello

submission deadline 28 Feb 2027 | 5 articles | Viewed by 13623 | Submission Open

Keywords: lung cancer; non-small cell lung cancer; small cell lung cancer; chemotherapy; targeted therapy; immunotherapy; drug resistance; drug delivery

(This special issue belongs to the Section Molecular Oncology)

Functions and Applications of Natural Products: 2nd Edition

edited by

Seung-Hong Lee

submission deadline 28 Feb 2027 | 7 articles | Viewed by 12918 | Submission Open

Keywords: natural products; biomedicine/phytomedicine; biologically active extracts and compounds; pharmacological and toxicological mechanisms of action

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Regulation and Targeting of Ferroptosis in Tumor and Beyond (Second Edition)

edited by

Yong Teng

submission deadline 28 Feb 2027 | 3 articles | Viewed by 10829 | Submission Open

Keywords: ferroptosis; iron; tumor survival and cell death; oxidation; drug development; anti-cancer strategies

(This special issue belongs to the Section Molecular Oncology)

Oxidative and Redox Signalling in Neurological Diseases

edited by

Malamati Kourti

submission deadline 28 Feb 2027 | 4 articles | Viewed by 10467 | Submission Open

Keywords: gasotransmitters; neurological diseases; oxidative stress; redox signalling; reactive oxygen species (ROS); neuroinflammation; mitochondrial dysfunction; cell death/apoptosis; nitrosative stress; endogenous gas signalling; neuromodulation; neurovascular coupling; therapeutic strategies; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathology of the Placenta in Pregnancy Complications

edited by

Zoltan Kozinszky

and

Andrea Suranyi

submission deadline 28 Feb 2027 | 6 articles | Viewed by 7694 | Submission Open

Keywords: pregnancy complications; placental histology; biomarker; trophoblast invasion; molecular diagnostics and therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Review Papers in Molecular Immunology, 3rd Edition

edited by

Manlio Ferrarini

and

Vincenzo Barnaba

submission deadline 28 Feb 2027 | 1 articles | Viewed by 6927 | Submission Open

Keywords: molecular immunology; review; immune cells

(This special issue belongs to the Section Molecular Immunology)

Neurodegenerative Diseases: Genetic Bases and Pathogenetic Mechanisms

edited by Emanuele Panza

submission deadline 28 Feb 2027 | 3 articles | Viewed by 6850 | Submission Open

Keywords: neurodegenerative diseases; molecular and cellular pathways; pathogenetic mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Skin Extracellular Matrix and Basement Membrane

edited by

Ju Hee Lee

submission deadline 28 Feb 2027 | 4 articles | Viewed by 6849 | Submission Open

Keywords: extracellular matrix; basement membrane; skin regeneration; cutaneous reconstruction; acellular dermal matrix; wound healing; fibrosis; scar; skin aging; biologic scaffold; tissue repair; regenerative dermatology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuropharmacological Innovations in Treating Neurodegenerative Diseases

edited by

Gabriela Cioca

submission deadline 28 Feb 2027 | 1 articles | Viewed by 6750 | Submission Open

Keywords: neuropharmacology; neurodegenerative disorders; targeted drug delivery; blood–brain barrier permeability; synaptic modulation; neuroprotective agents; disease-modifying therapies; molecular mechanisms of neurodegeneration; innovative drug targets; translational neuroscience

(This special issue belongs to the Section Molecular Neurobiology)

Genetic and Metabolic Molecular Research of Lysosomal Storage Disease: 5th Edition

edited by

Grzegorz Wegrzyn

submission deadline 28 Feb 2027 | 4 articles | Viewed by 6493 | Submission Open

Keywords: lysosomal storage diseases; molecular mechanisms of genetic disorders metabolic diseases; accumulation of macromolecules in cells; enzyme replacement therapy; hematopoietic stem cell transplantation gene therapy; substrate reduction therapy; translational research; novel therapies for genetic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Phytochemicals and Antioxidants in Health and Disease Modulation

edited by

Natalia Kurhaluk

submission deadline 28 Feb 2027 | 3 articles | Viewed by 6397 | Submission Open

Keywords: phytochemical bioactive compounds; antioxidant mechanisms; oxidative stress modulation; chronic disease prevention; inflammatory signalling pathways; molecular health effects; bioavailability and metabolism; flavonoid biological activity; polyphenol therapeutic potential; disease modulation strategies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Pathogenesis and Treatments of Head and Neck Cancer: 2nd Edition

edited by

Marko Tarle

submission deadline 28 Feb 2027 | 3 articles | Viewed by 6128 | Submission Open

Keywords: HNSCC; premalignant changes; tumor microenvironment; molecular biomarkers; targeted therapy; oral tumorigenesis; molecular pathogenesis; tumor biology; tumor immunology

(This special issue belongs to the Section Molecular Oncology)

In Silico Approaches to Drug Design and Discovery

edited by

Alejandro Speck-Planche

submission deadline 28 Feb 2027 | 3 articles | Viewed by 6046 | Submission Open

Keywords: chemoinformatics; computational de novo design and generative AI methods; machine learning; deep learning; molecular modeling; pharmacophore modeling; molecular docking; molecular dynamics; QSAR/QSPR; virtual screening

(This special issue belongs to the Section Molecular Informatics)

Advances in Basic and Translational Research in Colorectal Cancer

edited by

Gina Gheorghe

submission deadline 28 Feb 2027 | 2 articles | Viewed by 5915 | Submission Open

Keywords: colorectal cancer; diagnostic and prognostic biomarkers; genetic and epigenetic alterations; MMR/MSI; cytokine profiling; inflammatory mediators; gut microbiota; tumor microenvironment; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Advances in Neurodegenerative Diseases: Research, Challenges, and Perspectives

edited by Constantin Ailioaie

submission deadline 28 Feb 2027 | 2 articles | Viewed by 5704 | Submission Open

Keywords: Alzheimer’s disease; Parkinson’s disease; dementia spectrum disorders; pathogenic mechanisms; biomarkers; advanced imaging; artificial intelligence–guided diagnosis; nanomedicine and targeted drug delivery; photomedicine; precision medicine

(This special issue belongs to the Section Molecular Neurobiology)

25th Anniversary of IJMS: Updates and Advances in Molecular Toxicology

edited by

Marco E. M. Peluso

submission deadline 28 Feb 2027 | 5 articles | Viewed by 5635 | Submission Open

Keywords: molecular toxicology; biomarkers; mechanisms of toxicity; xenobiotics; cancer diagnosis

(This special issue belongs to the Section Molecular Toxicology)

From Drug Design to Mechanistic Understanding and Resistance

edited by

Yuan Ma

and

Yan-Fang Xian

submission deadline 28 Feb 2027 | 3 articles | Viewed by 5625 | Submission Open

Keywords: drug resistance; drug discovery; targeted protein degradation; systems pharmacology; structural biology

(This special issue belongs to the Section Molecular Pharmacology)

25th Anniversary of IJMS: Updates and Advances in "Molecular Biophysics"

edited by

Vladimir N. Uversky

submission deadline 28 Feb 2027 | 6 articles | Viewed by 5489 | Submission Open

Keywords: biomolecular interactions; biomolecular NMR; biophysics; chaperones; computational modeling; computer simulations; crystal thermodynamics; DNA structure and dynamics; drug–receptor interactions; enzymology; fluorescence imaging; genome structure; inter-molecular interactions; intrinsically disordered proteins; ion channels; macromolecular crystallography; macromolecular structure and dynamics; membrane dynamics; microcalorimetry; molecular dynamics; molecular imprinting; molecular mechanics; molecular modeling; molecular simulations; molecular modeling; molecular structure; molecular recognition; nucleic acid–protein interactions; post-translational modifications; protein design; protein–DNA interactions; protein engineering; protein–ligand binding; protein–membrane interactions; protein structure and folding; RNA structure; single-molecule techniques; spectroscopic techniques; statistical mechanics; structure–function relationships; structure prediction; thermodynamics; transient kinetic techniques; transmembrane proteins; x-ray crystallography

(This special issue belongs to the Section Molecular Biophysics)

Molecular Mechanisms of Nitric Oxide in Cardiovascular System

edited by

Elena Grossini

submission deadline 28 Feb 2027 | 2 articles | Viewed by 5440 | Submission Open

Keywords: heart; nitric oxide; oxidative stress; pathways; protection; therapy; vascular

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Gut Microbiota—Its Role and Molecular Mechanisms in Nutritional Health

edited by

Xi Ma

and Peng Tan

submission deadline 28 Feb 2027 | 3 articles | Viewed by 5336 | Submission Open

Keywords: gut microbiota; microbiome; mucosal immunity; probiotics; omics; dysbiosis; microbiota–host interactions; microbiota manipulation

(This special issue belongs to the Section Molecular Microbiology)

Oxidative Stress and Disease: Basic and Biochemical Approaches

edited by

Giuseppe Bruschetta

submission deadline 28 Feb 2027 | 3 articles | Viewed by 5207 | Submission Open

Keywords: aging; antioxidant mechanisms; cancer; cytokines; enzymatic pathways; inflammatory processes; oxidative stress; reactive oxygen species (ROS)

(This special issue belongs to the Section Molecular Biology)

Advanced Research of Plant-Pathogen Interaction

edited by

Hyong Woo Choi

submission deadline 28 Feb 2027 | 2 articles | Viewed by 5142 | Submission Open

Keywords: molecular plant-pathogen interactions; pathogen detection; secondary metabolism; multi-omics approaches; antibiotic resistance

(This special issue belongs to the Section Molecular Plant Sciences)

Drosophila: A Versatile Model in Biology and Medicine—3rd Edition

edited by

Roberto Piergentili

submission deadline 28 Feb 2027 | 6 articles | Viewed by 4777 | Submission Open

Keywords: model organism; human disease; inherited disease; cancer; neurodegeneration; rare disease; genetics

(This special issue belongs to the Section Molecular Biology)

Gene Regulation and Neurotoxicity in Alcohol Related Pathologies

edited by

Stefano Casalotti

submission deadline 28 Feb 2027 | 1 articles | Viewed by 4756 | Submission Open

Keywords: alcohol; ethanol; gene expression; neurotoxicity; epigenetics; polymorphisms; neu-rons; glial cell; plasticity

(This special issue belongs to the Section Molecular Neurobiology)

Viral Infections and Host Antiviral Responses: Molecular Mechanisms and Molecular Regulation

edited by Hong Jia

submission deadline 28 Feb 2027 | 6 articles | Viewed by 4752 | Submission Open

Keywords: antiviral immunity; viral entry; host–virus interaction; innate immunity; interferon signaling; viral immune evasion; non-coding RNAs; post-translational modifications; molecular therapeutics; viral pathogenesis

(This special issue belongs to the Section Molecular Microbiology)

Conversion and Valorization of Lignocellulosic Biomass

edited by

Loredana Marcolongo

submission deadline 28 Feb 2027 | 3 articles | Viewed by 4749 | Submission Open

Keywords: lignocellulosic biomass; vegetal and agro processing wast; catalytic and biocatalytic conversion; value added products; lignocellulosic platform; bioprocessing; biorefinery; green chemistry; circular economy, bioeconomy

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Toxicity: Identifying Biomarkers and Molecular Pathways Involved in Toxicological Responses

edited by Irma Martha Medina Díaz

submission deadline 28 Feb 2027 | 3 articles | Viewed by 4739 | Submission Open

Keywords: biomarkers; molecular pathways; chemical exposure assessment; environmental exposure; human health; public health toxicology

(This special issue belongs to the Section Molecular Toxicology)

Molecular Insights and Therapeutic Advances in Atherosclerosis

edited by

Zhu Bo

submission deadline 28 Feb 2027 | 1 articles | Viewed by 4736 | Submission Open

Keywords: atherosclerosis; molecular mechanisms; lipid metabolism; inflammation; endothelial dysfunction; RNA therapeutics; nanomedicine; cardiovascular disease; biomarkers; translational medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Interactions Between Microbes and Hosts: Physiology, Pathology and Treatment—Second Edition

edited by

Emira D’Amico

submission deadline 28 Feb 2027 | 7 articles | Viewed by 4654 | Submission Open

Keywords: microbial infection; microbes–host interaction; virulence factors; molecular and cell biology; antimicrobial therapy; antibiotics; antimicrobial peptides; resistance mechanisms

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Molecular and Cellular Approaches to Tuberculosis Pathogenesis, Treatment and Prevention

edited by

Selvakumar Subbian

submission deadline 28 Feb 2027 | 2 articles | Viewed by 4549 | Submission Open

Keywords: tuberculosis (TB); animal models of mycobacterium infections; molecular pathogenesis; host-directed therapy (HDT); nanoparticle drug delivery; vaccine development; cellular immunology; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

From Electronic Structure to Application: Computational Insights into Bioactive and Functional Molecules

edited by

Karolina Kula

submission deadline 28 Feb 2027 | 2 articles | Viewed by 4501 | Submission Open

Keywords: molecular design; molecular modeling; substituent effect; reactivity descriptors; biological potential; in silico study; physicochemical properties; ADME; PASS; QSAR

(This special issue belongs to the Section Molecular Informatics)

Osteoblast Differentiation in Human Health and Disease

edited by

Younho Han

submission deadline 28 Feb 2027 | 3 articles | Viewed by 4254 | Submission Open

Keywords: osteoblast differentiation; bone remodeling; mesenchymal stem cells; skeletal diseases; osteogenesis; bone mineralization; osteoporosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Adhesion, Invasion, and Metastasis in Cancer Progression

edited by

Pinar Uysal-Onganer

submission deadline 28 Feb 2027 | 5 articles | Viewed by 4192 | Submission Open

Keywords: cancer metastasis; cellular adhesion; invasion and migration; noncoding RNAs; EMT; Wnt/β-catenin signalling; tumour microenvironment; biomarkers; AI-driven metastasis prediction

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Radiation Oncology: Mechanisms, Immunotherapy and Innovation

edited by Jasna But-Hadžić

submission deadline 28 Feb 2027 | 3 articles | Viewed by 4175 | Submission Open

Keywords: molecular radiation oncology; DNA damage response; immunoradiotherapy; radiosensitization; tumor–immune interactions; radiogenomics; predictive biomarkers; combination therapies; translational radiobiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

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