Pathogenesis and Treatments of Head and Neck Cancer: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 89
Special Issue Editor
2. School of Dental Medicine, University of Zagreb, 10 000 Zagreb, Croatia
Interests: oral cancer; head and neck cancer; cancer therapy; molecular biomarkers; maxillofacial surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Head and neck cancer (HNSCC) is the sixth most common cancer worldwide and is a major public health problem due to its high mortality rate, despite the strong development of diagnostic and therapeutic methods in recent decades. The main risk factors are the consumption of alcohol and tobacco products and human papillomavirus (HPV) infection, which is responsible for a significant increase in incidence in the younger population. Patients with the same clinical and patho-histologic features often have a different disease prognosis. This suggests that the biological behavior of HNSCC and interpersonal differences require further investigation. New biomarkers that can help us diagnose tumors early, more accurately determine the risk of malignant transformation of precancerous lesions, identify more aggressive tumors, and detect disease recurrence and distant metastases could greatly improve the survival of patients with HNSCC.
In this Special Issue, we encourage the publication of scientific papers that provide new insight into genetic, molecular, and phenotypic changes in the pathogenesis of HNSCC, the tumor microenvironment, circulating tumor cells, therapeutic strategies that target important changes in tumor cells and their environment, and the use of artificial intelligence (AI) in the early diagnosis, treatment, and follow-up of patients with HNSCC.
Dr. Marko Tarle
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- HNSCC
- premalignant changes
- tumor microenvironment
- molecular biomarkers
- targeted therapy
- oral tumorigenesis
- molecular pathogenesis
- tumor biology
- tumor immunology
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
