Molecular Insights and Therapeutic Advances in Atherosclerosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 4648
Editor
Special Issue Information
Dear Colleagues,
Atherosclerosis remains a leading cause of cardiovascular morbidity and mortality worldwide, driven by complex interactions among lipid metabolism, inflammation, endothelial dysfunction, and genetic factors. Rapid advances in molecular biology, multi-omics technologies, and targeted therapeutics are transforming our understanding of atherogenesis and enabling the development of more precise diagnostic and treatment strategies.
This Special Issue aims to highlight cutting-edge research elucidating the molecular mechanisms that initiate and propagate atherosclerotic disease, as well as emerging therapeutic approaches designed to halt or reverse its progression. We welcome original research articles, reviews, and perspectives that advance current knowledge and foster innovation in translational and clinical applications.
Topics of interest include, but are not limited to, the following:
- Molecular and cellular mechanisms underlying plaque formation, progression, and instability;
- Lipid metabolism, lipoprotein biology, and regulatory pathways;
- Inflammatory and immune signaling in vascular pathology;
- Endothelial and smooth muscle cell biology;
- Novel biomarkers and diagnostic strategies;
- Gene- and RNA-based therapeutics, nanoparticle delivery systems, and targeted interventions;
- Preclinical models and translational studies;
- Systems biology, multi-omics, and computational approaches in atherosclerosis.
This Special Issue seeks to provide a comprehensive platform for advancing molecular insights and accelerating therapeutic breakthroughs in atherosclerosis.
Dr. Zhu Bo
Guest Editor
Manuscript Submission Information
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Keywords
- atherosclerosis
- molecular mechanisms
- lipid metabolism
- inflammation
- endothelial dysfunction
- RNA therapeutics
- nanomedicine
- cardiovascular disease
- biomarkers
- translational medicine
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