Adhesion, Invasion, and Metastasis in Cancer Progression
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 7
Special Issue Editor
Interests: non-coding RNAs; molecular oncology; tumour microenvironment; Wnt signalling; prostate cancer; breast cancer; pancreatic ductal adenocarcinoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metastasis is the leading cause of cancer-related mortality and remains a significant challenge in clinical oncology. The process involves a cascade of events including cell adhesion, extracellular matrix remodelling, invasion, intravasation, and colonization of distant tissues. While significant advances have been made in understanding the genetic and molecular basis of tumour progression, the mechanisms underlying metastatic spread, particularly those linked to cellular adhesion and invasion, remain incompletely understood.
This Special Issue aims to highlight recent advances in the molecular and cellular mechanisms driving cancer cell adhesion, invasion, and metastasis. We invite original research articles, reviews, and short communications that address key regulators of metastatic progression, including noncoding RNAs, epithelial–mesenchymal transition (EMT), Wnt signalling, tumour microenvironment and novel therapeutic approaches targeting metastatic niches.
We especially welcome studies that combine molecular biology with translational or clinical insights, as well as bioinformatics analyses that uncover new biomarkers or predictive models for metastatic disease.
Dr. Pinar Uysal-Onganer
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- cancer metastasis
- cellular adhesion
- invasion and migration
- noncoding RNAs
- EMT
- Wnt/β-catenin signalling
- tumour microenvironment
- biomarkers
- AI-driven metastasis prediction
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