Molecular Biology of Senescence and Anti-Aging Strategies

Dear Colleagues,

Senescence, a natural aging process, is a complex interplay of genetic, epigenetic, and environmental factors. To counteract its effects, researchers are exploring innovative anti-aging strategies. Genetic interventions, including the manipulation of longevity-associated genes, show promise in enhancing cellular repair mechanisms. Caloric restriction and nutrient sensing, proven to extend lifespan in various organisms, are under scrutiny for their impact on aging pathways. Senolytic and senomorphic drugs aim to eliminate or modify senescent cells, potentially delaying the progression of age-related diseases. Telomere maintenance strategies, focused on preserving chromosomal integrity, also offer avenues for combating cellular senescence and promoting healthier aging.

IJMS sets up this Special Issue, focusing on the current understanding and future research directions regarding the molecular mechanisms of senescence and anti-aging strategies. We welcome original research articles and review articles relating to this hot topic.

Dr. Nicola Alessio
Dr. James T. Arnone
Guest Editors

Manuscript Submission Information

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