Advances in Epithelial-Mesenchymal Transition (EMT)

Dear Colleagues,

The epithelial–mesenchymal transition (EMT) is a process that leads to the transdifferentiation of epithelial cells into motile mesenchymal cells. This is an essential event in development, wound healing, and stem cell behaviour, and contributes pathologically to fibrosis and cancer progression.

The cell differentiation is regulated by several transcription factors and molecular mechanisms that still remain unknown. During EMT, cell–cell and cell–extracellular matrix interactions are remodelled, and a new transcriptional programme is activated to promote the modifications in cellular morphology and functions. We invite colleagues to contribute editorials, original research articles, or review papers with recent findings on the mechanisms and roles of EMT in normal and neoplastic tissues, during physiological and pathological processes.

Prof. Dr. Oriana Trubiani
Dr. Francesca Diomede
Dr. Jacopo Pizzicanella
Dr. Guya Marconi
Collection Editors

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