Molecular Biology of Senescence

Dear Colleagues,

Senescence is the process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing cell death. The word senescence can refer to either cellular senescence or to aging of the whole organism. Several studies correlate cellular senescence to aging, as it largely contributes to reducing tissue functions and renewal. On the other side, it is also believed to promote protective anticancer mechanisms leading to tumor growth arrest or, paradoxically, the persistence of senescent cells in tissues that may promote cancer onset. 

IJMS sets up this Special Issue focusing on the current understanding and future research directions regarding the molecular mechanisms of senescence and the related disease. We warmly welcome original research article and review articles relating to this hot topic.

Dr. Nicola Alessio
Guest Editor

Manuscript Submission Information

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